Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | AACTGGA,MIR-145 |
| Enrichment Score (ES) | -0.35992855 |
| Normalized Enrichment Score (NES) | -1.4640774 |
| Nominal p-value | 0.026156941 |
| FDR q-value | 0.30155194 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SLC25A25 | SLC25A25 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 | 16 | 0.282 | 0.0495 | No |
| 2 | IRS1 | IRS1 Entrez, Source | insulin receptor substrate 1 | 549 | 0.114 | 0.0298 | No |
| 3 | BSN | BSN Entrez, Source | bassoon (presynaptic cytomatrix protein) | 564 | 0.113 | 0.0490 | No |
| 4 | SEMA3A | SEMA3A Entrez, Source | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 755 | 0.102 | 0.0529 | No |
| 5 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 1027 | 0.091 | 0.0487 | No |
| 6 | GGTL3 | GGTL3 Entrez, Source | gamma-glutamyltransferase-like 3 | 1378 | 0.078 | 0.0363 | No |
| 7 | SLC6A15 | SLC6A15 Entrez, Source | solute carrier family 6, member 15 | 1509 | 0.074 | 0.0399 | No |
| 8 | PTGFR | PTGFR Entrez, Source | prostaglandin F receptor (FP) | 1661 | 0.071 | 0.0412 | No |
| 9 | ADD3 | ADD3 Entrez, Source | adducin 3 (gamma) | 1701 | 0.070 | 0.0508 | No |
| 10 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 1832 | 0.067 | 0.0530 | No |
| 11 | CUGBP2 | CUGBP2 Entrez, Source | CUG triplet repeat, RNA binding protein 2 | 1969 | 0.063 | 0.0541 | No |
| 12 | DNAJB11 | DNAJB11 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 11 | 2175 | 0.058 | 0.0490 | No |
| 13 | CCNL1 | CCNL1 Entrez, Source | cyclin L1 | 2308 | 0.055 | 0.0490 | No |
| 14 | EFNA3 | EFNA3 Entrez, Source | ephrin-A3 | 2420 | 0.053 | 0.0502 | No |
| 15 | SLC1A2 | SLC1A2 Entrez, Source | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 2558 | 0.051 | 0.0489 | No |
| 16 | SCN3A | SCN3A Entrez, Source | sodium channel, voltage-gated, type III, alpha | 2647 | 0.049 | 0.0511 | No |
| 17 | EIF4A2 | EIF4A2 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 2 | 2944 | 0.044 | 0.0367 | No |
| 18 | HERC6 | HERC6 Entrez, Source | hect domain and RLD 6 | 2992 | 0.043 | 0.0408 | No |
| 19 | ZBTB10 | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 3181 | 0.040 | 0.0339 | No |
| 20 | NEDD4L | NEDD4L Entrez, Source | neural precursor cell expressed, developmentally down-regulated 4-like | 3266 | 0.039 | 0.0346 | No |
| 21 | RASSF5 | RASSF5 Entrez, Source | Ras association (RalGDS/AF-6) domain family 5 | 3313 | 0.038 | 0.0380 | No |
| 22 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 3390 | 0.037 | 0.0388 | No |
| 23 | RGS7 | RGS7 Entrez, Source | regulator of G-protein signalling 7 | 3598 | 0.034 | 0.0293 | No |
| 24 | RGS3 | RGS3 Entrez, Source | regulator of G-protein signalling 3 | 3616 | 0.034 | 0.0340 | No |
| 25 | ABLIM2 | ABLIM2 Entrez, Source | actin binding LIM protein family, member 2 | 3639 | 0.033 | 0.0383 | No |
| 26 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 3699 | 0.033 | 0.0397 | No |
| 27 | CDC37L1 | CDC37L1 Entrez, Source | CDC37 cell division cycle 37 homolog (S. cerevisiae)-like 1 | 3922 | 0.029 | 0.0283 | No |
| 28 | LOX | LOX Entrez, Source | lysyl oxidase | 3959 | 0.029 | 0.0307 | No |
| 29 | CHKB | CHKB Entrez, Source | choline kinase beta | 4072 | 0.027 | 0.0272 | No |
| 30 | SOX9 | SOX9 Entrez, Source | SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) | 4534 | 0.021 | -0.0038 | No |
| 31 | ACACA | ACACA Entrez, Source | acetyl-Coenzyme A carboxylase alpha | 4652 | 0.020 | -0.0090 | No |
| 32 | SACM1L | SACM1L Entrez, Source | SAC1 suppressor of actin mutations 1-like (yeast) | 4684 | 0.020 | -0.0078 | No |
| 33 | ADAM19 | ADAM19 Entrez, Source | ADAM metallopeptidase domain 19 (meltrin beta) | 4765 | 0.019 | -0.0104 | No |
| 34 | SENP2 | SENP2 Entrez, Source | SUMO1/sentrin/SMT3 specific peptidase 2 | 5045 | 0.016 | -0.0287 | No |
| 35 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5303 | 0.013 | -0.0459 | No |
| 36 | NUDT4 | NUDT4 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 5570 | 0.009 | -0.0643 | No |
| 37 | CABP1 | CABP1 Entrez, Source | calcium binding protein 1 (calbrain) | 5653 | 0.008 | -0.0689 | No |
| 38 | ZDHHC9 | ZDHHC9 Entrez, Source | zinc finger, DHHC-type containing 9 | 5722 | 0.008 | -0.0727 | No |
| 39 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 5734 | 0.008 | -0.0722 | No |
| 40 | SLC4A4 | SLC4A4 Entrez, Source | solute carrier family 4, sodium bicarbonate cotransporter, member 4 | 5747 | 0.007 | -0.0718 | No |
| 41 | GPHN | GPHN Entrez, Source | gephyrin | 5880 | 0.006 | -0.0807 | No |
| 42 | SOX11 | SOX11 Entrez, Source | SRY (sex determining region Y)-box 11 | 5904 | 0.005 | -0.0814 | No |
| 43 | ACVR2A | ACVR2A Entrez, Source | activin A receptor, type IIA | 5957 | 0.005 | -0.0845 | No |
| 44 | ANGPT2 | ANGPT2 Entrez, Source | angiopoietin 2 | 6000 | 0.005 | -0.0868 | No |
| 45 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 6085 | 0.004 | -0.0925 | No |
| 46 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 6188 | 0.003 | -0.0997 | No |
| 47 | EIF4EBP2 | EIF4EBP2 Entrez, Source | eukaryotic translation initiation factor 4E binding protein 2 | 6607 | -0.002 | -0.1309 | No |
| 48 | TRIM2 | TRIM2 Entrez, Source | tripartite motif-containing 2 | 6833 | -0.004 | -0.1472 | No |
| 49 | LENG8 | LENG8 Entrez, Source | leukocyte receptor cluster (LRC) member 8 | 6900 | -0.005 | -0.1514 | No |
| 50 | FBXL10 | FBXL10 Entrez, Source | F-box and leucine-rich repeat protein 10 | 6940 | -0.005 | -0.1534 | No |
| 51 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 7529 | -0.011 | -0.1959 | No |
| 52 | TM9SF4 | TM9SF4 Entrez, Source | transmembrane 9 superfamily protein member 4 | 7788 | -0.013 | -0.2129 | No |
| 53 | NEDD9 | NEDD9 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 9 | 7794 | -0.013 | -0.2109 | No |
| 54 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 7902 | -0.015 | -0.2164 | No |
| 55 | FLNB | FLNB Entrez, Source | filamin B, beta (actin binding protein 278) | 7935 | -0.015 | -0.2161 | No |
| 56 | GABARAPL2 | GABARAPL2 Entrez, Source | GABA(A) receptor-associated protein-like 2 | 8016 | -0.016 | -0.2193 | No |
| 57 | ACTB | ACTB Entrez, Source | actin, beta | 8105 | -0.017 | -0.2229 | No |
| 58 | RTKN | RTKN Entrez, Source | rhotekin | 8116 | -0.017 | -0.2207 | No |
| 59 | RAB14 | RAB14 Entrez, Source | RAB14, member RAS oncogene family | 8275 | -0.018 | -0.2293 | No |
| 60 | SCAMP3 | SCAMP3 Entrez, Source | secretory carrier membrane protein 3 | 8496 | -0.021 | -0.2422 | No |
| 61 | ADPGK | ADPGK Entrez, Source | ADP-dependent glucokinase | 8497 | -0.021 | -0.2385 | No |
| 62 | BLOC1S2 | BLOC1S2 Entrez, Source | biogenesis of lysosome-related organelles complex-1, subunit 2 | 8566 | -0.021 | -0.2398 | No |
| 63 | PAPD4 | PAPD4 Entrez, Source | PAP associated domain containing 4 | 8642 | -0.022 | -0.2414 | No |
| 64 | DYRK1A | DYRK1A Entrez, Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 9041 | -0.026 | -0.2667 | No |
| 65 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 9098 | -0.027 | -0.2661 | No |
| 66 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 9381 | -0.030 | -0.2820 | No |
| 67 | ACBD3 | ACBD3 Entrez, Source | acyl-Coenzyme A binding domain containing 3 | 9513 | -0.031 | -0.2863 | No |
| 68 | GPIAP1 | GPIAP1 Entrez, Source | GPI-anchored membrane protein 1 | 9675 | -0.034 | -0.2924 | No |
| 69 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 9796 | -0.035 | -0.2952 | No |
| 70 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 9840 | -0.036 | -0.2920 | No |
| 71 | PTP4A2 | PTP4A2 Entrez, Source | protein tyrosine phosphatase type IVA, member 2 | 10102 | -0.038 | -0.3048 | No |
| 72 | QKI | QKI Entrez, Source | quaking homolog, KH domain RNA binding (mouse) | 10287 | -0.041 | -0.3114 | No |
| 73 | UBE2Z | UBE2Z Entrez, Source | ubiquitin-conjugating enzyme E2Z (putative) | 10670 | -0.046 | -0.3321 | No |
| 74 | HERC4 | HERC4 Entrez, Source | hect domain and RLD 4 | 10776 | -0.048 | -0.3315 | No |
| 75 | SNX27 | SNX27 Entrez, Source | sorting nexin family member 27 | 11154 | -0.054 | -0.3502 | Yes |
| 76 | CBFB | CBFB Entrez, Source | core-binding factor, beta subunit | 11282 | -0.057 | -0.3497 | Yes |
| 77 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 11304 | -0.057 | -0.3410 | Yes |
| 78 | ACSL4 | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 11316 | -0.057 | -0.3316 | Yes |
| 79 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 11353 | -0.058 | -0.3239 | Yes |
| 80 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 11447 | -0.059 | -0.3202 | Yes |
| 81 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 11497 | -0.060 | -0.3131 | Yes |
| 82 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 11512 | -0.061 | -0.3032 | Yes |
| 83 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 11730 | -0.065 | -0.3078 | Yes |
| 84 | DAG1 | DAG1 Entrez, Source | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 11785 | -0.067 | -0.2999 | Yes |
| 85 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11928 | -0.071 | -0.2979 | Yes |
| 86 | NAP1L1 | NAP1L1 Entrez, Source | nucleosome assembly protein 1-like 1 | 11929 | -0.071 | -0.2852 | Yes |
| 87 | AP1G1 | AP1G1 Entrez, Source | adaptor-related protein complex 1, gamma 1 subunit | 12092 | -0.076 | -0.2839 | Yes |
| 88 | PXN | PXN Entrez, Source | paxillin | 12322 | -0.084 | -0.2862 | Yes |
| 89 | MYO5A | MYO5A Entrez, Source | myosin VA (heavy chain 12, myoxin) | 12504 | -0.092 | -0.2834 | Yes |
| 90 | CD47 | CD47 Entrez, Source | CD47 molecule | 12518 | -0.093 | -0.2677 | Yes |
| 91 | UXS1 | UXS1 Entrez, Source | UDP-glucuronate decarboxylase 1 | 12546 | -0.094 | -0.2528 | Yes |
| 92 | TNFRSF11B | TNFRSF11B Entrez, Source | tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) | 12718 | -0.104 | -0.2470 | Yes |
| 93 | PDCD4 | PDCD4 Entrez, Source | programmed cell death 4 (neoplastic transformation inhibitor) | 12722 | -0.105 | -0.2284 | Yes |
| 94 | TAGLN2 | TAGLN2 Entrez, Source | transgelin 2 | 12779 | -0.109 | -0.2130 | Yes |
| 95 | RASA2 | RASA2 Entrez, Source | RAS p21 protein activator 2 | 12895 | -0.120 | -0.2000 | Yes |
| 96 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 12899 | -0.121 | -0.1785 | Yes |
| 97 | AKAP9 | AKAP9 Entrez, Source | A kinase (PRKA) anchor protein (yotiao) 9 | 12906 | -0.122 | -0.1570 | Yes |
| 98 | NET1 | NET1 Entrez, Source | neuroepithelial cell transforming gene 1 | 12910 | -0.122 | -0.1352 | Yes |
| 99 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 12948 | -0.126 | -0.1154 | Yes |
| 100 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 13036 | -0.137 | -0.0973 | Yes |
| 101 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 13072 | -0.143 | -0.0741 | Yes |
| 102 | PLCE1 | PLCE1 Entrez, Source | phospholipase C, epsilon 1 | 13205 | -0.194 | -0.0492 | Yes |
| 103 | ARHGAP24 | ARHGAP24 Entrez, Source | Rho GTPase activating protein 24 | 13313 | -0.331 | 0.0022 | Yes |
