Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | ACACTGG,MIR-199A,MIR-199B |
| Enrichment Score (ES) | -0.39424053 |
| Normalized Enrichment Score (NES) | -1.5317664 |
| Nominal p-value | 0.01923077 |
| FDR q-value | 0.27137342 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HLF | HLF Entrez, Source | hepatic leukemia factor | 402 | 0.125 | 0.0008 | No |
| 2 | HSPA5 | HSPA5 Entrez, Source | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 618 | 0.109 | 0.0116 | No |
| 3 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 816 | 0.099 | 0.0212 | No |
| 4 | SLC24A3 | SLC24A3 Entrez, Source | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 914 | 0.095 | 0.0374 | No |
| 5 | RNF38 | RNF38 Entrez, Source | ring finger protein 38 | 1038 | 0.090 | 0.0505 | No |
| 6 | UBAP1 | UBAP1 Entrez, Source | ubiquitin associated protein 1 | 1292 | 0.080 | 0.0513 | No |
| 7 | ST6GAL1 | ST6GAL1 Entrez, Source | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 1574 | 0.073 | 0.0482 | No |
| 8 | CREM | CREM Entrez, Source | cAMP responsive element modulator | 1593 | 0.073 | 0.0648 | No |
| 9 | CUGBP2 | CUGBP2 Entrez, Source | CUG triplet repeat, RNA binding protein 2 | 1969 | 0.063 | 0.0522 | No |
| 10 | ATP2B2 | ATP2B2 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 2 | 2135 | 0.059 | 0.0544 | No |
| 11 | PAX3 | PAX3 Entrez, Source | paired box gene 3 (Waardenburg syndrome 1) | 2190 | 0.058 | 0.0647 | No |
| 12 | CCNL1 | CCNL1 Entrez, Source | cyclin L1 | 2308 | 0.055 | 0.0695 | No |
| 13 | LIN7C | LIN7C Entrez, Source | lin-7 homolog C (C. elegans) | 2644 | 0.049 | 0.0565 | No |
| 14 | SULF1 | SULF1 Entrez, Source | sulfatase 1 | 3160 | 0.041 | 0.0277 | No |
| 15 | MARCH7 | MARCH7 Entrez, Source | membrane-associated ring finger (C3HC4) 7 | 3217 | 0.040 | 0.0334 | No |
| 16 | ATXN3 | ATXN3 Entrez, Source | ataxin 3 | 3236 | 0.040 | 0.0418 | No |
| 17 | KL | KL Entrez, Source | klotho | 3988 | 0.029 | -0.0077 | No |
| 18 | TAF9B | TAF9B Entrez, Source | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 5144 | 0.014 | -0.0912 | No |
| 19 | RAD23B | RAD23B Entrez, Source | RAD23 homolog B (S. cerevisiae) | 5366 | 0.012 | -0.1049 | No |
| 20 | EPHA7 | EPHA7 Entrez, Source | EPH receptor A7 | 5521 | 0.010 | -0.1141 | No |
| 21 | TSPAN5 | TSPAN5 Entrez, Source | tetraspanin 5 | 5710 | 0.008 | -0.1263 | No |
| 22 | DDX3X | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 5728 | 0.008 | -0.1257 | No |
| 23 | RSN | RSN Entrez, Source | restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) | 5729 | 0.008 | -0.1238 | No |
| 24 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 5868 | 0.006 | -0.1328 | No |
| 25 | ACVR2A | ACVR2A Entrez, Source | activin A receptor, type IIA | 5957 | 0.005 | -0.1382 | No |
| 26 | TXNL1 | TXNL1 Entrez, Source | thioredoxin-like 1 | 6029 | 0.004 | -0.1425 | No |
| 27 | KPNA4 | KPNA4 Entrez, Source | karyopherin alpha 4 (importin alpha 3) | 6453 | -0.000 | -0.1743 | No |
| 28 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 6569 | -0.002 | -0.1825 | No |
| 29 | UNC84A | UNC84A Entrez, Source | unc-84 homolog A (C. elegans) | 6599 | -0.002 | -0.1842 | No |
| 30 | ZFP91 | ZFP91 Entrez, Source | zinc finger protein 91 homolog (mouse) | 6850 | -0.004 | -0.2020 | No |
| 31 | AKAP1 | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 6923 | -0.005 | -0.2062 | No |
| 32 | PPP1R2 | PPP1R2 Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 6926 | -0.005 | -0.2052 | No |
| 33 | CSDC2 | CSDC2 Entrez, Source | cold shock domain containing C2, RNA binding | 7375 | -0.009 | -0.2367 | No |
| 34 | CCDC43 | CCDC43 Entrez, Source | coiled-coil domain containing 43 | 7600 | -0.012 | -0.2507 | No |
| 35 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 7724 | -0.013 | -0.2568 | No |
| 36 | MAFB | MAFB Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) | 7949 | -0.015 | -0.2699 | No |
| 37 | CDC73 | CDC73 Entrez, Source | cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 8134 | -0.017 | -0.2796 | No |
| 38 | ABCC5 | ABCC5 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 8737 | -0.023 | -0.3192 | No |
| 39 | RAB10 | RAB10 Entrez, Source | RAB10, member RAS oncogene family | 8900 | -0.025 | -0.3253 | No |
| 40 | PDE4D | PDE4D Entrez, Source | phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) | 9157 | -0.028 | -0.3377 | No |
| 41 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 9302 | -0.029 | -0.3414 | No |
| 42 | GIT1 | GIT1 Entrez, Source | G protein-coupled receptor kinase interactor 1 | 9515 | -0.031 | -0.3496 | No |
| 43 | M6PR | M6PR Entrez, Source | mannose-6-phosphate receptor (cation dependent) | 9614 | -0.033 | -0.3488 | No |
| 44 | ERBB4 | ERBB4 Entrez, Source | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 9620 | -0.033 | -0.3410 | No |
| 45 | GPIAP1 | GPIAP1 Entrez, Source | GPI-anchored membrane protein 1 | 9675 | -0.034 | -0.3367 | No |
| 46 | FUBP1 | FUBP1 Entrez, Source | far upstream element (FUSE) binding protein 1 | 9728 | -0.034 | -0.3321 | No |
| 47 | EIF5B | EIF5B Entrez, Source | eukaryotic translation initiation factor 5B | 9729 | -0.034 | -0.3236 | No |
| 48 | TSPAN6 | TSPAN6 Entrez, Source | tetraspanin 6 | 9780 | -0.035 | -0.3188 | No |
| 49 | APPBP2 | APPBP2 Entrez, Source | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 9965 | -0.037 | -0.3236 | No |
| 50 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 10151 | -0.039 | -0.3279 | No |
| 51 | VPS26A | VPS26A Entrez, Source | vacuolar protein sorting 26 homolog A (yeast) | 10264 | -0.040 | -0.3263 | No |
| 52 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 10920 | -0.050 | -0.3633 | No |
| 53 | PPM1B | PPM1B Entrez, Source | protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform | 11331 | -0.058 | -0.3800 | Yes |
| 54 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 11447 | -0.059 | -0.3739 | Yes |
| 55 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 11568 | -0.062 | -0.3677 | Yes |
| 56 | NCOA2 | NCOA2 Entrez, Source | nuclear receptor coactivator 2 | 11605 | -0.063 | -0.3549 | Yes |
| 57 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 11666 | -0.064 | -0.3435 | Yes |
| 58 | WDR44 | WDR44 Entrez, Source | WD repeat domain 44 | 11679 | -0.064 | -0.3285 | Yes |
| 59 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 11730 | -0.065 | -0.3161 | Yes |
| 60 | GARNL1 | GARNL1 Entrez, Source | GTPase activating Rap/RanGAP domain-like 1 | 11901 | -0.070 | -0.3116 | Yes |
| 61 | BTRC | BTRC Entrez, Source | beta-transducin repeat containing | 12010 | -0.073 | -0.3016 | Yes |
| 62 | FZD6 | FZD6 Entrez, Source | frizzled homolog 6 (Drosophila) | 12054 | -0.074 | -0.2864 | Yes |
| 63 | AP1G1 | AP1G1 Entrez, Source | adaptor-related protein complex 1, gamma 1 subunit | 12092 | -0.076 | -0.2705 | Yes |
| 64 | DDR1 | DDR1 Entrez, Source | discoidin domain receptor family, member 1 | 12120 | -0.077 | -0.2535 | Yes |
| 65 | IKBKB | IKBKB Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 12168 | -0.078 | -0.2376 | Yes |
| 66 | PXN | PXN Entrez, Source | paxillin | 12322 | -0.084 | -0.2285 | Yes |
| 67 | MYEF2 | MYEF2 Entrez, Source | myelin expression factor 2 | 12369 | -0.086 | -0.2107 | Yes |
| 68 | BCAM | BCAM Entrez, Source | basal cell adhesion molecule (Lutheran blood group) | 12684 | -0.102 | -0.2091 | Yes |
| 69 | PODXL | PODXL Entrez, Source | podocalyxin-like | 12713 | -0.104 | -0.1854 | Yes |
| 70 | GPRC5A | GPRC5A Entrez, Source | G protein-coupled receptor, family C, group 5, member A | 13055 | -0.141 | -0.1763 | Yes |
| 71 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 13097 | -0.150 | -0.1423 | Yes |
| 72 | FZD4 | FZD4 Entrez, Source | frizzled homolog 4 (Drosophila) | 13170 | -0.170 | -0.1056 | Yes |
| 73 | PVRL2 | PVRL2 Entrez, Source | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 13237 | -0.215 | -0.0572 | Yes |
| 74 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13284 | -0.263 | 0.0044 | Yes |
