Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | ACTIN_CYTOSKELETON |
| Enrichment Score (ES) | -0.4138765 |
| Normalized Enrichment Score (NES) | -1.5985898 |
| Nominal p-value | 0.008403362 |
| FDR q-value | 0.2392088 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SPTBN4 | SPTBN4 Entrez, Source | spectrin, beta, non-erythrocytic 4 | 71 | 0.192 | 0.0380 | No |
| 2 | AVIL | AVIL Entrez, Source | advillin | 385 | 0.126 | 0.0430 | No |
| 3 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 441 | 0.122 | 0.0665 | No |
| 4 | TNNI3 | TNNI3 Entrez, Source | troponin I type 3 (cardiac) | 617 | 0.109 | 0.0780 | No |
| 5 | ABRA | ABRA Entrez, Source | actin-binding Rho activating protein | 657 | 0.107 | 0.0991 | No |
| 6 | SNIP | SNIP Entrez, Source | - | 1237 | 0.082 | 0.0741 | No |
| 7 | ACTL7B | ACTL7B Entrez, Source | actin-like 7B | 1856 | 0.066 | 0.0424 | No |
| 8 | AMPH | AMPH Entrez, Source | amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) | 1857 | 0.066 | 0.0573 | No |
| 9 | MYH7 | MYH7 Entrez, Source | myosin, heavy chain 7, cardiac muscle, beta | 2024 | 0.062 | 0.0588 | No |
| 10 | MYL3 | MYL3 Entrez, Source | myosin, light chain 3, alkali; ventricular, skeletal, slow | 2080 | 0.061 | 0.0684 | No |
| 11 | SYNPO | SYNPO Entrez, Source | synaptopodin | 2217 | 0.057 | 0.0710 | No |
| 12 | ESPN | ESPN Entrez, Source | espin | 3000 | 0.043 | 0.0218 | No |
| 13 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 3475 | 0.036 | -0.0059 | No |
| 14 | HAP1 | HAP1 Entrez, Source | huntingtin-associated protein 1 (neuroan 1) | 3573 | 0.034 | -0.0054 | No |
| 15 | ABLIM2 | ABLIM2 Entrez, Source | actin binding LIM protein family, member 2 | 3639 | 0.033 | -0.0028 | No |
| 16 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 3835 | 0.031 | -0.0106 | No |
| 17 | BMF | BMF Entrez, Source | Bcl2 modifying factor | 4020 | 0.028 | -0.0181 | No |
| 18 | CORO1A | CORO1A Entrez, Source | coronin, actin binding protein, 1A | 4124 | 0.027 | -0.0198 | No |
| 19 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 4433 | 0.023 | -0.0379 | No |
| 20 | MYH6 | MYH6 Entrez, Source | myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) | 4670 | 0.020 | -0.0512 | No |
| 21 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 6620 | -0.002 | -0.1974 | No |
| 22 | SEPT9 | SEPT9 Entrez, Source | septin 9 | 6891 | -0.005 | -0.2167 | No |
| 23 | KALRN | KALRN Entrez, Source | kalirin, RhoGEF kinase | 7103 | -0.007 | -0.2311 | No |
| 24 | LSP1 | LSP1 Entrez, Source | lymphocyte-specific protein 1 | 7298 | -0.009 | -0.2438 | No |
| 25 | SEPT7 | SEPT7 Entrez, Source | septin 7 | 7594 | -0.011 | -0.2634 | No |
| 26 | BIN1 | BIN1 Entrez, Source | bridging integrator 1 | 7729 | -0.013 | -0.2706 | No |
| 27 | FLNB | FLNB Entrez, Source | filamin B, beta (actin binding protein 278) | 7935 | -0.015 | -0.2827 | No |
| 28 | CAPZA2 | CAPZA2 Entrez, Source | capping protein (actin filament) muscle Z-line, alpha 2 | 8236 | -0.018 | -0.3012 | No |
| 29 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 8248 | -0.018 | -0.2979 | No |
| 30 | CLIC5 | CLIC5 Entrez, Source | chloride intracellular channel 5 | 8412 | -0.020 | -0.3057 | No |
| 31 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 8579 | -0.022 | -0.3133 | No |
| 32 | ARPC1A | ARPC1A Entrez, Source | actin related protein 2/3 complex, subunit 1A, 41kDa | 8606 | -0.022 | -0.3103 | No |
| 33 | DYNLL2 | DYNLL2 Entrez, Source | dynein, light chain, LC8-type 2 | 8613 | -0.022 | -0.3058 | No |
| 34 | ACTR2 | ACTR2 Entrez, Source | ARP2 actin-related protein 2 homolog (yeast) | 8777 | -0.024 | -0.3128 | No |
| 35 | MYO9B | MYO9B Entrez, Source | myosin IXB | 8864 | -0.025 | -0.3137 | No |
| 36 | ACTR1B | ACTR1B Entrez, Source | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | 9228 | -0.028 | -0.3346 | No |
| 37 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 9840 | -0.036 | -0.3726 | No |
| 38 | GYS2 | GYS2 Entrez, Source | glycogen synthase 2 (liver) | 10212 | -0.040 | -0.3916 | No |
| 39 | DCTN2 | DCTN2 Entrez, Source | dynactin 2 (p50) | 10509 | -0.044 | -0.4040 | Yes |
| 40 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 10631 | -0.045 | -0.4029 | Yes |
| 41 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 10717 | -0.047 | -0.3988 | Yes |
| 42 | ARPC1B | ARPC1B Entrez, Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 10805 | -0.048 | -0.3945 | Yes |
| 43 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 10920 | -0.050 | -0.3918 | Yes |
| 44 | CAPZB | CAPZB Entrez, Source | capping protein (actin filament) muscle Z-line, beta | 11020 | -0.051 | -0.3877 | Yes |
| 45 | WASF1 | WASF1 Entrez, Source | WAS protein family, member 1 | 11176 | -0.054 | -0.3871 | Yes |
| 46 | WASL | WASL Entrez, Source | Wiskott-Aldrich syndrome-like | 11185 | -0.055 | -0.3754 | Yes |
| 47 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 11304 | -0.057 | -0.3714 | Yes |
| 48 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11323 | -0.057 | -0.3598 | Yes |
| 49 | MARCKS | MARCKS Entrez, Source | myristoylated alanine-rich protein kinase C substrate | 11501 | -0.060 | -0.3595 | Yes |
| 50 | MYOM1 | MYOM1 Entrez, Source | myomesin 1 (skelemin) 185kDa | 11511 | -0.061 | -0.3465 | Yes |
| 51 | SMTN | SMTN Entrez, Source | smoothelin | 11739 | -0.066 | -0.3487 | Yes |
| 52 | DAG1 | DAG1 Entrez, Source | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 11785 | -0.067 | -0.3370 | Yes |
| 53 | ACTC1 | ACTC1 Entrez, Source | actin, alpha, cardiac muscle 1 | 11932 | -0.071 | -0.3320 | Yes |
| 54 | SLC9A3R1 | SLC9A3R1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 12376 | -0.086 | -0.3459 | Yes |
| 55 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 12392 | -0.087 | -0.3275 | Yes |
| 56 | CASK | CASK Entrez, Source | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 12444 | -0.088 | -0.3114 | Yes |
| 57 | SORBS2 | SORBS2 Entrez, Source | sorbin and SH3 domain containing 2 | 12635 | -0.099 | -0.3034 | Yes |
| 58 | MYO1C | MYO1C Entrez, Source | myosin IC | 12875 | -0.118 | -0.2947 | Yes |
| 59 | PDLIM5 | PDLIM5 Entrez, Source | PDZ and LIM domain 5 | 12904 | -0.122 | -0.2692 | Yes |
| 60 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12937 | -0.125 | -0.2434 | Yes |
| 61 | TPM4 | TPM4 Entrez, Source | tropomyosin 4 | 12972 | -0.128 | -0.2170 | Yes |
| 62 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 13185 | -0.179 | -0.1926 | Yes |
| 63 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -0.905 | 0.0000 | Yes |
