Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | ADIPOGENESIS_HMSC_CLASS3_UP |
| Enrichment Score (ES) | 0.52002233 |
| Normalized Enrichment Score (NES) | 1.8151962 |
| Nominal p-value | 0.002004008 |
| FDR q-value | 0.08051992 |
| FWER p-Value | 0.97 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 36 | 0.229 | 0.0876 | Yes |
| 2 | NFE2 | NFE2 Entrez, Source | nuclear factor (erythroid-derived 2), 45kDa | 81 | 0.187 | 0.1580 | Yes |
| 3 | LPIN1 | LPIN1 Entrez, Source | lipin 1 | 182 | 0.151 | 0.2102 | Yes |
| 4 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 215 | 0.147 | 0.2657 | Yes |
| 5 | PHKG1 | PHKG1 Entrez, Source | phosphorylase kinase, gamma 1 (muscle) | 362 | 0.129 | 0.3055 | Yes |
| 6 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 502 | 0.118 | 0.3415 | Yes |
| 7 | FASN | FASN Entrez, Source | fatty acid synthase | 607 | 0.110 | 0.3770 | Yes |
| 8 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 612 | 0.109 | 0.4199 | Yes |
| 9 | INSIG1 | INSIG1 Entrez, Source | insulin induced gene 1 | 978 | 0.092 | 0.4288 | Yes |
| 10 | ADFP | ADFP Entrez, Source | adipose differentiation-related protein | 1046 | 0.090 | 0.4592 | Yes |
| 11 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 1076 | 0.088 | 0.4919 | Yes |
| 12 | MGP | MGP Entrez, Source | matrix Gla protein | 1341 | 0.079 | 0.5032 | Yes |
| 13 | LIPE | LIPE Entrez, Source | lipase, hormone-sensitive | 1739 | 0.069 | 0.5006 | Yes |
| 14 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 1832 | 0.067 | 0.5200 | Yes |
| 15 | NPTXR | NPTXR Entrez, Source | neuronal pentraxin receptor | 2230 | 0.057 | 0.5126 | No |
| 16 | ITGAM | ITGAM Entrez, Source | integrin, alpha M (complement component 3 receptor 3 subunit) | 2576 | 0.050 | 0.5065 | No |
| 17 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 2858 | 0.045 | 0.5032 | No |
| 18 | ACACA | ACACA Entrez, Source | acetyl-Coenzyme A carboxylase alpha | 4652 | 0.020 | 0.3763 | No |
| 19 | CYBRD1 | CYBRD1 Entrez, Source | cytochrome b reductase 1 | 4778 | 0.019 | 0.3743 | No |
| 20 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 5438 | 0.011 | 0.3291 | No |
| 21 | SLC27A4 | SLC27A4 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 4 | 5500 | 0.010 | 0.3285 | No |
| 22 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 6246 | 0.002 | 0.2732 | No |
| 23 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 6322 | 0.001 | 0.2680 | No |
| 24 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 6361 | 0.001 | 0.2654 | No |
| 25 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 6494 | -0.001 | 0.2557 | No |
| 26 | ACSL5 | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 6561 | -0.002 | 0.2514 | No |
| 27 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6842 | -0.004 | 0.2319 | No |
| 28 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 6967 | -0.005 | 0.2247 | No |
| 29 | GM2A | GM2A Entrez, Source | GM2 ganglioside activator | 7133 | -0.007 | 0.2150 | No |
| 30 | NID1 | NID1 Entrez, Source | nidogen 1 | 7136 | -0.007 | 0.2176 | No |
| 31 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 7743 | -0.013 | 0.1772 | No |
| 32 | LEPREL1 | LEPREL1 Entrez, Source | leprecan-like 1 | 8320 | -0.019 | 0.1413 | No |
| 33 | PPP2R1B | PPP2R1B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform | 9012 | -0.026 | 0.0997 | No |
| 34 | STX3 | STX3 Entrez, Source | syntaxin 3 | 9160 | -0.028 | 0.0995 | No |
| 35 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 9382 | -0.030 | 0.0947 | No |
| 36 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 9892 | -0.036 | 0.0707 | No |
| 37 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 10356 | -0.041 | 0.0521 | No |
| 38 | NAB1 | NAB1 Entrez, Source | NGFI-A binding protein 1 (EGR1 binding protein 1) | 10612 | -0.045 | 0.0507 | No |
| 39 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 11234 | -0.056 | 0.0260 | No |
| 40 | STOM | STOM Entrez, Source | stomatin | 11510 | -0.061 | 0.0292 | No |
| 41 | ACACB | ACACB Entrez, Source | acetyl-Coenzyme A carboxylase beta | 11612 | -0.063 | 0.0464 | No |
| 42 | CDH13 | CDH13 Entrez, Source | cadherin 13, H-cadherin (heart) | 11616 | -0.063 | 0.0710 | No |
| 43 | GAS6 | GAS6 Entrez, Source | growth arrest-specific 6 | 11976 | -0.072 | 0.0725 | No |
| 44 | TMEM23 | TMEM23 Entrez, Source | transmembrane protein 23 | 12115 | -0.076 | 0.0923 | No |
