Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | APOPTOSIS_GENMAPP |
| Enrichment Score (ES) | -0.51517963 |
| Normalized Enrichment Score (NES) | -1.7194474 |
| Nominal p-value | 0.0020661156 |
| FDR q-value | 0.14996724 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1411 | 0.077 | -0.0590 | No |
| 2 | GZMB | GZMB Entrez, Source | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 1567 | 0.073 | -0.0262 | No |
| 3 | FASLG | FASLG Entrez, Source | Fas ligand (TNF superfamily, member 6) | 3426 | 0.036 | -0.1437 | No |
| 4 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 4653 | 0.020 | -0.2237 | No |
| 5 | JUN | JUN Entrez, Source | jun oncogene | 4841 | 0.018 | -0.2268 | No |
| 6 | BIRC2 | BIRC2 Entrez, Source | baculoviral IAP repeat-containing 2 | 5286 | 0.013 | -0.2524 | No |
| 7 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 5475 | 0.010 | -0.2602 | No |
| 8 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 5839 | 0.006 | -0.2837 | No |
| 9 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 6812 | -0.004 | -0.3544 | No |
| 10 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 6874 | -0.004 | -0.3563 | No |
| 11 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 7260 | -0.008 | -0.3802 | No |
| 12 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 7301 | -0.009 | -0.3780 | No |
| 13 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 7416 | -0.010 | -0.3807 | No |
| 14 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 7500 | -0.010 | -0.3805 | No |
| 15 | BAX | BAX Entrez, Source | BCL2-associated X protein | 7784 | -0.013 | -0.3936 | No |
| 16 | CASP7 | CASP7 Entrez, Source | caspase 7, apoptosis-related cysteine peptidase | 8153 | -0.017 | -0.4109 | No |
| 17 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 8457 | -0.020 | -0.4213 | No |
| 18 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 8779 | -0.024 | -0.4311 | No |
| 19 | PRF1 | PRF1 Entrez, Source | perforin 1 (pore forming protein) | 8817 | -0.024 | -0.4192 | No |
| 20 | BIRC4 | BIRC4 Entrez, Source | baculoviral IAP repeat-containing 4 | 8879 | -0.025 | -0.4088 | No |
| 21 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 9040 | -0.026 | -0.4047 | No |
| 22 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 9174 | -0.028 | -0.3978 | No |
| 23 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 10368 | -0.041 | -0.4622 | No |
| 24 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 10649 | -0.045 | -0.4556 | No |
| 25 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 11443 | -0.059 | -0.4790 | Yes |
| 26 | MAPK10 | MAPK10 Entrez, Source | mitogen-activated protein kinase 10 | 11586 | -0.062 | -0.4519 | Yes |
| 27 | BID | BID Entrez, Source | BH3 interacting domain death agonist | 12134 | -0.077 | -0.4461 | Yes |
| 28 | FADD | FADD Entrez, Source | Fas (TNFRSF6)-associated via death domain | 12156 | -0.078 | -0.4004 | Yes |
| 29 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12178 | -0.079 | -0.3541 | Yes |
| 30 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 12319 | -0.083 | -0.3139 | Yes |
| 31 | FAS | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 12841 | -0.114 | -0.2836 | Yes |
| 32 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 12964 | -0.127 | -0.2154 | Yes |
| 33 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 13071 | -0.143 | -0.1361 | Yes |
| 34 | APAF1 | APAF1 Entrez, Source | apoptotic peptidase activating factor | 13280 | -0.257 | 0.0047 | Yes |
