Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | BASSO_REGULATORY_HUBS |
| Enrichment Score (ES) | -0.38030612 |
| Normalized Enrichment Score (NES) | -1.4970149 |
| Nominal p-value | 0.016260162 |
| FDR q-value | 0.27497247 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 164 | 0.155 | 0.0309 | No |
| 2 | LAPTM5 | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 1212 | 0.083 | -0.0249 | No |
| 3 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 1430 | 0.077 | -0.0199 | No |
| 4 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 1596 | 0.073 | -0.0121 | No |
| 5 | LGALS1 | LGALS1 Entrez, Source | lectin, galactoside-binding, soluble, 1 (galectin 1) | 1865 | 0.066 | -0.0140 | No |
| 6 | PRKCB1 | PRKCB1 Entrez, Source | protein kinase C, beta 1 | 2052 | 0.061 | -0.0110 | No |
| 7 | LGALS9 | LGALS9 Entrez, Source | lectin, galactoside-binding, soluble, 9 (galectin 9) | 2245 | 0.056 | -0.0098 | No |
| 8 | BYSL | BYSL Entrez, Source | bystin-like | 2678 | 0.048 | -0.0289 | No |
| 9 | EPOR | EPOR Entrez, Source | erythropoietin receptor | 4411 | 0.023 | -0.1530 | No |
| 10 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 4450 | 0.023 | -0.1495 | No |
| 11 | GABARAP | GABARAP Entrez, Source | GABA(A) receptor-associated protein | 4565 | 0.021 | -0.1523 | No |
| 12 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 4803 | 0.018 | -0.1650 | No |
| 13 | NISCH | NISCH Entrez, Source | nischarin | 5244 | 0.013 | -0.1945 | No |
| 14 | ITPR2 | ITPR2 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 2 | 5533 | 0.010 | -0.2134 | No |
| 15 | TIMM17A | TIMM17A Entrez, Source | translocase of inner mitochondrial membrane 17 homolog A (yeast) | 5700 | 0.008 | -0.2237 | No |
| 16 | SLC4A3 | SLC4A3 Entrez, Source | solute carrier family 4, anion exchanger, member 3 | 5718 | 0.008 | -0.2228 | No |
| 17 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 6376 | 0.000 | -0.2722 | No |
| 18 | TGOLN2 | TGOLN2 Entrez, Source | trans-golgi network protein 2 | 6479 | -0.001 | -0.2798 | No |
| 19 | RPS26 | RPS26 Entrez, Source | ribosomal protein S26 | 6666 | -0.003 | -0.2931 | No |
| 20 | PSMB7 | PSMB7 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 7 | 6692 | -0.003 | -0.2942 | No |
| 21 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 6758 | -0.003 | -0.2981 | No |
| 22 | HPRT1 | HPRT1 Entrez, Source | hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) | 6770 | -0.004 | -0.2980 | No |
| 23 | RUVBL2 | RUVBL2 Entrez, Source | RuvB-like 2 (E. coli) | 6886 | -0.005 | -0.3054 | No |
| 24 | PSMB5 | PSMB5 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 5 | 7049 | -0.006 | -0.3159 | No |
| 25 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 7114 | -0.007 | -0.3188 | No |
| 26 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 7116 | -0.007 | -0.3170 | No |
| 27 | EBNA1BP2 | EBNA1BP2 Entrez, Source | EBNA1 binding protein 2 | 7242 | -0.008 | -0.3242 | No |
| 28 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 7500 | -0.010 | -0.3407 | No |
| 29 | EIF2S1 | EIF2S1 Entrez, Source | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 7641 | -0.012 | -0.3479 | No |
| 30 | TCEB1 | TCEB1 Entrez, Source | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 7679 | -0.012 | -0.3473 | No |
| 31 | TCP1 | TCP1 Entrez, Source | t-complex 1 | 7728 | -0.013 | -0.3473 | No |
| 32 | BIN1 | BIN1 Entrez, Source | bridging integrator 1 | 7729 | -0.013 | -0.3438 | No |
| 33 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 7738 | -0.013 | -0.3408 | No |
| 34 | WDR18 | WDR18 Entrez, Source | WD repeat domain 18 | 8004 | -0.016 | -0.3564 | No |
| 35 | HSPE1 | HSPE1 Entrez, Source | heat shock 10kDa protein 1 (chaperonin 10) | 8023 | -0.016 | -0.3533 | No |
| 36 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 8303 | -0.019 | -0.3691 | No |
| 37 | PSMB2 | PSMB2 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 2 | 8376 | -0.019 | -0.3692 | No |
| 38 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 8512 | -0.021 | -0.3735 | Yes |
| 39 | HHEX | HHEX Entrez, Source | homeobox, hematopoietically expressed | 8540 | -0.021 | -0.3697 | Yes |
| 40 | SSRP1 | SSRP1 Entrez, Source | structure specific recognition protein 1 | 8587 | -0.022 | -0.3671 | Yes |
| 41 | MGEA5 | MGEA5 Entrez, Source | meningioma expressed antigen 5 (hyaluronidase) | 8610 | -0.022 | -0.3627 | Yes |
| 42 | ZMYND11 | ZMYND11 Entrez, Source | zinc finger, MYND domain containing 11 | 8725 | -0.023 | -0.3648 | Yes |
| 43 | SAR1A | SAR1A Entrez, Source | SAR1 gene homolog A (S. cerevisiae) | 8742 | -0.023 | -0.3596 | Yes |
| 44 | TOMM40 | TOMM40 Entrez, Source | translocase of outer mitochondrial membrane 40 homolog (yeast) | 8940 | -0.025 | -0.3673 | Yes |
| 45 | AFG3L2 | AFG3L2 Entrez, Source | AFG3 ATPase family gene 3-like 2 (yeast) | 9113 | -0.027 | -0.3728 | Yes |
| 46 | PLCB2 | PLCB2 Entrez, Source | phospholipase C, beta 2 | 9169 | -0.028 | -0.3692 | Yes |
| 47 | SERBP1 | SERBP1 Entrez, Source | SERPINE1 mRNA binding protein 1 | 9194 | -0.028 | -0.3632 | Yes |
| 48 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 9198 | -0.028 | -0.3556 | Yes |
| 49 | BUD31 | BUD31 Entrez, Source | BUD31 homolog (yeast) | 9213 | -0.028 | -0.3488 | Yes |
| 50 | TPP1 | TPP1 Entrez, Source | tripeptidyl peptidase I | 9225 | -0.028 | -0.3418 | Yes |
| 51 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 9329 | -0.029 | -0.3414 | Yes |
| 52 | RBM5 | RBM5 Entrez, Source | RNA binding motif protein 5 | 9365 | -0.030 | -0.3357 | Yes |
| 53 | PRDX3 | PRDX3 Entrez, Source | peroxiredoxin 3 | 9635 | -0.033 | -0.3468 | Yes |
| 54 | CTSH | CTSH Entrez, Source | cathepsin H | 9659 | -0.033 | -0.3392 | Yes |
| 55 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 9913 | -0.036 | -0.3482 | Yes |
| 56 | ASNS | ASNS Entrez, Source | asparagine synthetase | 9972 | -0.037 | -0.3423 | Yes |
| 57 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 10067 | -0.038 | -0.3388 | Yes |
| 58 | SSBP1 | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 10100 | -0.038 | -0.3305 | Yes |
| 59 | MRPL12 | MRPL12 Entrez, Source | mitochondrial ribosomal protein L12 | 10545 | -0.044 | -0.3518 | Yes |
| 60 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 10666 | -0.046 | -0.3481 | Yes |
| 61 | ITPR1 | ITPR1 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 1 | 10751 | -0.047 | -0.3413 | Yes |
| 62 | NME1 | NME1 Entrez, Source | non-metastatic cells 1, protein (NM23A) expressed in | 10783 | -0.048 | -0.3303 | Yes |
| 63 | POLR2F | POLR2F Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide F | 10800 | -0.048 | -0.3182 | Yes |
| 64 | BLMH | BLMH Entrez, Source | bleomycin hydrolase | 10846 | -0.049 | -0.3080 | Yes |
| 65 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 10939 | -0.050 | -0.3010 | Yes |
| 66 | ZYX | ZYX Entrez, Source | zyxin | 11108 | -0.053 | -0.2989 | Yes |
| 67 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 11374 | -0.058 | -0.3026 | Yes |
| 68 | PSMD1 | PSMD1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 11377 | -0.058 | -0.2866 | Yes |
| 69 | TEP1 | TEP1 Entrez, Source | telomerase-associated protein 1 | 11764 | -0.066 | -0.2972 | Yes |
| 70 | TUBG1 | TUBG1 Entrez, Source | tubulin, gamma 1 | 12486 | -0.090 | -0.3264 | Yes |
| 71 | MVP | MVP Entrez, Source | major vault protein | 12888 | -0.120 | -0.3233 | Yes |
| 72 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 13078 | -0.144 | -0.2974 | Yes |
| 73 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 13152 | -0.163 | -0.2575 | Yes |
| 74 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13165 | -0.168 | -0.2116 | Yes |
| 75 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13194 | -0.185 | -0.1622 | Yes |
| 76 | S100A4 | S100A4 Entrez, Source | S100 calcium binding protein A4 | 13306 | -0.310 | -0.0843 | Yes |
| 77 | AHNAK | AHNAK Entrez, Source | AHNAK nucleoprotein (desmoyokin) | 13307 | -0.312 | 0.0026 | Yes |
