Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | BRCA1_OVEREXP_UP |
| Enrichment Score (ES) | -0.36530346 |
| Normalized Enrichment Score (NES) | -1.5204116 |
| Nominal p-value | 0.006012024 |
| FDR q-value | 0.27227002 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TUBB3 | TUBB3 Entrez, Source | tubulin, beta 3 | 32 | 0.237 | 0.0407 | No |
| 2 | ENPP2 | ENPP2 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | 429 | 0.123 | 0.0332 | No |
| 3 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 491 | 0.118 | 0.0502 | No |
| 4 | FSTL1 | FSTL1 Entrez, Source | follistatin-like 1 | 1010 | 0.091 | 0.0276 | No |
| 5 | ATP6V0A1 | ATP6V0A1 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a1 | 1685 | 0.070 | -0.0106 | No |
| 6 | ADD3 | ADD3 Entrez, Source | adducin 3 (gamma) | 1701 | 0.070 | 0.0010 | No |
| 7 | GALNT3 | GALNT3 Entrez, Source | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) | 2156 | 0.059 | -0.0227 | No |
| 8 | CIRBP | CIRBP Entrez, Source | cold inducible RNA binding protein | 2222 | 0.057 | -0.0172 | No |
| 9 | SEPHS2 | SEPHS2 Entrez, Source | selenophosphate synthetase 2 | 2585 | 0.050 | -0.0355 | No |
| 10 | TITF1 | TITF1 Entrez, Source | thyroid transcription factor 1 | 3273 | 0.039 | -0.0804 | No |
| 11 | KCNK1 | KCNK1 Entrez, Source | potassium channel, subfamily K, member 1 | 3345 | 0.037 | -0.0789 | No |
| 12 | CYBA | CYBA Entrez, Source | cytochrome b-245, alpha polypeptide | 3471 | 0.036 | -0.0819 | No |
| 13 | ZFP36L1 | ZFP36L1 Entrez, Source | zinc finger protein 36, C3H type-like 1 | 3560 | 0.034 | -0.0822 | No |
| 14 | COPS8 | COPS8 Entrez, Source | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 3971 | 0.029 | -0.1080 | No |
| 15 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 4172 | 0.026 | -0.1184 | No |
| 16 | SSR1 | SSR1 Entrez, Source | signal sequence receptor, alpha (translocon-associated protein alpha) | 4186 | 0.026 | -0.1146 | No |
| 17 | TMED2 | TMED2 Entrez, Source | transmembrane emp24 domain trafficking protein 2 | 4236 | 0.025 | -0.1137 | No |
| 18 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 4239 | 0.025 | -0.1092 | No |
| 19 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 4458 | 0.022 | -0.1216 | No |
| 20 | KDELR2 | KDELR2 Entrez, Source | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 4645 | 0.020 | -0.1320 | No |
| 21 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 4780 | 0.019 | -0.1387 | No |
| 22 | FCGRT | FCGRT Entrez, Source | Fc fragment of IgG, receptor, transporter, alpha | 4923 | 0.017 | -0.1464 | No |
| 23 | RABGGTB | RABGGTB Entrez, Source | Rab geranylgeranyltransferase, beta subunit | 5146 | 0.014 | -0.1605 | No |
| 24 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 5163 | 0.014 | -0.1592 | No |
| 25 | LTB4DH | LTB4DH Entrez, Source | leukotriene B4 12-hydroxydehydrogenase | 5279 | 0.013 | -0.1655 | No |
| 26 | RAB1A | RAB1A Entrez, Source | RAB1A, member RAS oncogene family | 5561 | 0.009 | -0.1850 | No |
| 27 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 5682 | 0.008 | -0.1926 | No |
| 28 | TIMM17A | TIMM17A Entrez, Source | translocase of inner mitochondrial membrane 17 homolog A (yeast) | 5700 | 0.008 | -0.1925 | No |
| 29 | DDX3X | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 5728 | 0.008 | -0.1931 | No |
| 30 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 5828 | 0.006 | -0.1995 | No |
| 31 | NPC2 | NPC2 Entrez, Source | Niemann-Pick disease, type C2 | 5920 | 0.005 | -0.2054 | No |
| 32 | TMED10 | TMED10 Entrez, Source | transmembrane emp24-like trafficking protein 10 (yeast) | 6170 | 0.003 | -0.2237 | No |
| 33 | LUM | LUM Entrez, Source | lumican | 6250 | 0.002 | -0.2293 | No |
| 34 | TSNAX | TSNAX Entrez, Source | translin-associated factor X | 6324 | 0.001 | -0.2347 | No |
| 35 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6594 | -0.002 | -0.2547 | No |
| 36 | FGF9 | FGF9 Entrez, Source | fibroblast growth factor 9 (glia-activating factor) | 6646 | -0.002 | -0.2581 | No |
| 37 | RAB6A | RAB6A Entrez, Source | RAB6A, member RAS oncogene family | 6696 | -0.003 | -0.2613 | No |
| 38 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 6724 | -0.003 | -0.2628 | No |
| 39 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 6743 | -0.003 | -0.2635 | No |
| 40 | WWP1 | WWP1 Entrez, Source | WW domain containing E3 ubiquitin protein ligase 1 | 6766 | -0.003 | -0.2645 | No |
| 41 | PPP6C | PPP6C Entrez, Source | protein phosphatase 6, catalytic subunit | 6953 | -0.005 | -0.2777 | No |
| 42 | TEGT | TEGT Entrez, Source | testis enhanced gene transcript (BAX inhibitor 1) | 6960 | -0.005 | -0.2772 | No |
| 43 | RAB2 | RAB2 Entrez, Source | RAB2, member RAS oncogene family | 7067 | -0.006 | -0.2841 | No |
| 44 | TSG101 | TSG101 Entrez, Source | tumor susceptibility gene 101 | 7072 | -0.006 | -0.2832 | No |
| 45 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 7099 | -0.007 | -0.2840 | No |
| 46 | NID1 | NID1 Entrez, Source | nidogen 1 | 7136 | -0.007 | -0.2854 | No |
| 47 | UBE2D3 | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 7172 | -0.007 | -0.2868 | No |
| 48 | PPP4C | PPP4C Entrez, Source | protein phosphatase 4 (formerly X), catalytic subunit | 7406 | -0.010 | -0.3026 | No |
| 49 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 7416 | -0.010 | -0.3015 | No |
| 50 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 7517 | -0.011 | -0.3072 | No |
| 51 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 7778 | -0.013 | -0.3244 | No |
| 52 | TM9SF2 | TM9SF2 Entrez, Source | transmembrane 9 superfamily member 2 | 7785 | -0.013 | -0.3224 | No |
| 53 | CSNK1A1 | CSNK1A1 Entrez, Source | casein kinase 1, alpha 1 | 7832 | -0.014 | -0.3234 | No |
| 54 | PCBD1 | PCBD1 Entrez, Source | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) | 7882 | -0.014 | -0.3244 | No |
| 55 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 7897 | -0.014 | -0.3229 | No |
| 56 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 8088 | -0.017 | -0.3342 | No |
| 57 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 8249 | -0.018 | -0.3430 | No |
| 58 | COPS2 | COPS2 Entrez, Source | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 8285 | -0.019 | -0.3422 | No |
| 59 | ABCD3 | ABCD3 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 3 | 8286 | -0.019 | -0.3389 | No |
| 60 | TM9SF1 | TM9SF1 Entrez, Source | transmembrane 9 superfamily member 1 | 8347 | -0.019 | -0.3399 | No |
| 61 | EXOC5 | EXOC5 Entrez, Source | exocyst complex component 5 | 8479 | -0.020 | -0.3461 | No |
| 62 | PGRMC1 | PGRMC1 Entrez, Source | progesterone receptor membrane component 1 | 8487 | -0.021 | -0.3429 | No |
| 63 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 8491 | -0.021 | -0.3393 | No |
| 64 | JAK1 | JAK1 Entrez, Source | Janus kinase 1 (a protein tyrosine kinase) | 8495 | -0.021 | -0.3358 | No |
| 65 | NFYC | NFYC Entrez, Source | nuclear transcription factor Y, gamma | 8563 | -0.021 | -0.3370 | No |
| 66 | ARPC1A | ARPC1A Entrez, Source | actin related protein 2/3 complex, subunit 1A, 41kDa | 8606 | -0.022 | -0.3362 | No |
| 67 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 8609 | -0.022 | -0.3323 | No |
| 68 | ID4 | ID4 Entrez, Source | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 8674 | -0.023 | -0.3331 | No |
| 69 | SERINC3 | SERINC3 Entrez, Source | serine incorporator 3 | 8838 | -0.024 | -0.3410 | No |
| 70 | RDX | RDX Entrez, Source | radixin | 9144 | -0.027 | -0.3590 | No |
| 71 | ACTR1B | ACTR1B Entrez, Source | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | 9228 | -0.028 | -0.3601 | Yes |
| 72 | P2RX4 | P2RX4 Entrez, Source | purinergic receptor P2X, ligand-gated ion channel, 4 | 9274 | -0.029 | -0.3583 | Yes |
| 73 | SMC1A | SMC1A Entrez, Source | structural maintenance of chromosomes 1A | 9336 | -0.029 | -0.3575 | Yes |
| 74 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9337 | -0.029 | -0.3522 | Yes |
| 75 | TRAM1 | TRAM1 Entrez, Source | translocation associated membrane protein 1 | 9369 | -0.030 | -0.3491 | Yes |
| 76 | NEU1 | NEU1 Entrez, Source | sialidase 1 (lysosomal sialidase) | 9433 | -0.031 | -0.3483 | Yes |
| 77 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 9571 | -0.032 | -0.3528 | Yes |
| 78 | SCAMP1 | SCAMP1 Entrez, Source | secretory carrier membrane protein 1 | 9586 | -0.032 | -0.3479 | Yes |
| 79 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 9714 | -0.034 | -0.3513 | Yes |
| 80 | ADCYAP1 | ADCYAP1 Entrez, Source | adenylate cyclase activating polypeptide 1 (pituitary) | 9783 | -0.035 | -0.3501 | Yes |
| 81 | EXTL2 | EXTL2 Entrez, Source | exostoses (multiple)-like 2 | 9831 | -0.035 | -0.3472 | Yes |
| 82 | GUCY1B3 | GUCY1B3 Entrez, Source | guanylate cyclase 1, soluble, beta 3 | 9974 | -0.037 | -0.3512 | Yes |
| 83 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 10085 | -0.038 | -0.3525 | Yes |
| 84 | MFGE8 | MFGE8 Entrez, Source | milk fat globule-EGF factor 8 protein | 10130 | -0.039 | -0.3488 | Yes |
| 85 | PTPN1 | PTPN1 Entrez, Source | protein tyrosine phosphatase, non-receptor type 1 | 10210 | -0.040 | -0.3476 | Yes |
| 86 | STC1 | STC1 Entrez, Source | stanniocalcin 1 | 10297 | -0.041 | -0.3467 | Yes |
| 87 | ITGB3BP | ITGB3BP Entrez, Source | integrin beta 3 binding protein (beta3-endonexin) | 10308 | -0.041 | -0.3400 | Yes |
| 88 | HAGH | HAGH Entrez, Source | hydroxyacylglutathione hydrolase | 10339 | -0.041 | -0.3348 | Yes |
| 89 | HIST2H2AA3 | HIST2H2AA3 Entrez, Source | histone cluster 2, H2aa3 | 10493 | -0.043 | -0.3385 | Yes |
| 90 | DR1 | DR1 Entrez, Source | down-regulator of transcription 1, TBP-binding (negative cofactor 2) | 10653 | -0.046 | -0.3422 | Yes |
| 91 | PPP1R1A | PPP1R1A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 10735 | -0.047 | -0.3398 | Yes |
| 92 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 10835 | -0.049 | -0.3384 | Yes |
| 93 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 10926 | -0.050 | -0.3361 | Yes |
| 94 | FRAP1 | FRAP1 Entrez, Source | FK506 binding protein 12-rapamycin associated protein 1 | 10956 | -0.050 | -0.3291 | Yes |
| 95 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 11234 | -0.056 | -0.3399 | Yes |
| 96 | TAF11 | TAF11 Entrez, Source | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa | 11247 | -0.056 | -0.3307 | Yes |
| 97 | VAMP3 | VAMP3 Entrez, Source | vesicle-associated membrane protein 3 (cellubrevin) | 11346 | -0.058 | -0.3276 | Yes |
| 98 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 11629 | -0.063 | -0.3374 | Yes |
| 99 | SUCLG1 | SUCLG1 Entrez, Source | succinate-CoA ligase, GDP-forming, alpha subunit | 11767 | -0.066 | -0.3356 | Yes |
| 100 | KIF5B | KIF5B Entrez, Source | kinesin family member 5B | 11786 | -0.067 | -0.3248 | Yes |
| 101 | CD9 | CD9 Entrez, Source | CD9 molecule | 11802 | -0.067 | -0.3137 | Yes |
| 102 | PAM | PAM Entrez, Source | peptidylglycine alpha-amidating monooxygenase | 11839 | -0.068 | -0.3039 | Yes |
| 103 | ADD1 | ADD1 Entrez, Source | adducin 1 (alpha) | 12055 | -0.074 | -0.3066 | Yes |
| 104 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 12078 | -0.075 | -0.2946 | Yes |
| 105 | ALDH7A1 | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 12088 | -0.076 | -0.2815 | Yes |
| 106 | DEK | DEK Entrez, Source | DEK oncogene (DNA binding) | 12158 | -0.078 | -0.2725 | Yes |
| 107 | HMGN3 | HMGN3 Entrez, Source | high mobility group nucleosomal binding domain 3 | 12161 | -0.078 | -0.2584 | Yes |
| 108 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 12281 | -0.082 | -0.2525 | Yes |
| 109 | AGPS | AGPS Entrez, Source | alkylglycerone phosphate synthase | 12413 | -0.087 | -0.2465 | Yes |
| 110 | CXADR | CXADR Entrez, Source | coxsackie virus and adenovirus receptor | 12487 | -0.090 | -0.2355 | Yes |
| 111 | CD47 | CD47 Entrez, Source | CD47 molecule | 12518 | -0.093 | -0.2208 | Yes |
| 112 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 12685 | -0.102 | -0.2148 | Yes |
| 113 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 12899 | -0.121 | -0.2089 | Yes |
| 114 | WRB | WRB Entrez, Source | tryptophan rich basic protein | 12902 | -0.121 | -0.1869 | Yes |
| 115 | KIF2A | KIF2A Entrez, Source | kinesin heavy chain member 2A | 12962 | -0.127 | -0.1682 | Yes |
| 116 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 13011 | -0.133 | -0.1476 | Yes |
| 117 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 13084 | -0.146 | -0.1263 | Yes |
| 118 | PPIC | PPIC Entrez, Source | peptidylprolyl isomerase C (cyclophilin C) | 13186 | -0.179 | -0.1013 | Yes |
| 119 | TCEAL1 | TCEAL1 Entrez, Source | transcription elongation factor A (SII)-like 1 | 13287 | -0.265 | -0.0605 | Yes |
| 120 | GNAI1 | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 13318 | -0.354 | 0.0018 | Yes |
