Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | BRCA_PROGNOSIS_NEG |
| Enrichment Score (ES) | -0.42663467 |
| Normalized Enrichment Score (NES) | -1.4877313 |
| Nominal p-value | 0.039215688 |
| FDR q-value | 0.2797544 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 892 | 0.096 | -0.0268 | No |
| 2 | GNAZ | GNAZ Entrez, Source | guanine nucleotide binding protein (G protein), alpha z polypeptide | 1036 | 0.090 | 0.0003 | No |
| 3 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 1559 | 0.073 | -0.0082 | No |
| 4 | DCK | DCK Entrez, Source | deoxycytidine kinase | 1598 | 0.072 | 0.0195 | No |
| 5 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 1609 | 0.072 | 0.0491 | No |
| 6 | ADM | ADM Entrez, Source | adrenomedullin | 2189 | 0.058 | 0.0298 | No |
| 7 | NMU | NMU Entrez, Source | neuromedin U | 2876 | 0.045 | -0.0028 | No |
| 8 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 4135 | 0.026 | -0.0863 | No |
| 9 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 4407 | 0.023 | -0.0969 | No |
| 10 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 4780 | 0.019 | -0.1170 | No |
| 11 | SLC7A1 | SLC7A1 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 5188 | 0.014 | -0.1417 | No |
| 12 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 5631 | 0.009 | -0.1713 | No |
| 13 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 5696 | 0.008 | -0.1727 | No |
| 14 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 5875 | 0.006 | -0.1837 | No |
| 15 | ESM1 | ESM1 Entrez, Source | endothelial cell-specific molecule 1 | 5998 | 0.005 | -0.1909 | No |
| 16 | CDC42BPA | CDC42BPA Entrez, Source | CDC42 binding protein kinase alpha (DMPK-like) | 7499 | -0.010 | -0.2993 | No |
| 17 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 7738 | -0.013 | -0.3117 | No |
| 18 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 7800 | -0.014 | -0.3106 | No |
| 19 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 8512 | -0.021 | -0.3553 | No |
| 20 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 8724 | -0.023 | -0.3615 | No |
| 21 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 8905 | -0.025 | -0.3645 | No |
| 22 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 9093 | -0.027 | -0.3672 | No |
| 23 | DEGS1 | DEGS1 Entrez, Source | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | 9137 | -0.027 | -0.3590 | No |
| 24 | AURKA | AURKA Entrez, Source | aurora kinase A | 9667 | -0.034 | -0.3846 | No |
| 25 | MTDH | MTDH Entrez, Source | metadherin | 9730 | -0.034 | -0.3749 | No |
| 26 | PCTK1 | PCTK1 Entrez, Source | PCTAIRE protein kinase 1 | 9935 | -0.036 | -0.3749 | No |
| 27 | ASNS | ASNS Entrez, Source | asparagine synthetase | 9972 | -0.037 | -0.3621 | No |
| 28 | PTDSS1 | PTDSS1 Entrez, Source | phosphatidylserine synthase 1 | 10346 | -0.041 | -0.3728 | No |
| 29 | UCHL5 | UCHL5 Entrez, Source | ubiquitin carboxyl-terminal hydrolase L5 | 10426 | -0.042 | -0.3610 | No |
| 30 | MGAT4A | MGAT4A Entrez, Source | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A | 10535 | -0.044 | -0.3506 | No |
| 31 | MRPL13 | MRPL13 Entrez, Source | mitochondrial ribosomal protein L13 | 10935 | -0.050 | -0.3596 | No |
| 32 | SPBC25 | SPBC25 Entrez, Source | spindle pole body component 25 homolog (S. cerevisiae) | 11828 | -0.068 | -0.3980 | Yes |
| 33 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 11871 | -0.069 | -0.3721 | Yes |
| 34 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12131 | -0.077 | -0.3593 | Yes |
| 35 | MCCC1 | MCCC1 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) | 12336 | -0.085 | -0.3391 | Yes |
| 36 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 12679 | -0.101 | -0.3222 | Yes |
| 37 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 13078 | -0.144 | -0.2914 | Yes |
| 38 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 13151 | -0.163 | -0.2284 | Yes |
| 39 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13174 | -0.172 | -0.1578 | Yes |
| 40 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13196 | -0.186 | -0.0811 | Yes |
| 41 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 13248 | -0.219 | 0.0071 | Yes |
