Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | BRENTANI_DEATH |
| Enrichment Score (ES) | -0.43101007 |
| Normalized Enrichment Score (NES) | -1.5143106 |
| Nominal p-value | 0.021008404 |
| FDR q-value | 0.27981186 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CASP1 | CASP1 Entrez, Source | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 1348 | 0.079 | -0.0646 | No |
| 2 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1411 | 0.077 | -0.0332 | No |
| 3 | PLAGL1 | PLAGL1 Entrez, Source | pleiomorphic adenoma gene-like 1 | 2231 | 0.057 | -0.0683 | No |
| 4 | STK17B | STK17B Entrez, Source | serine/threonine kinase 17b (apoptosis-inducing) | 2348 | 0.055 | -0.0516 | No |
| 5 | LTA | LTA Entrez, Source | lymphotoxin alpha (TNF superfamily, member 1) | 3561 | 0.034 | -0.1267 | No |
| 6 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 4653 | 0.020 | -0.1994 | No |
| 7 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 4780 | 0.019 | -0.2002 | No |
| 8 | BAK1 | BAK1 Entrez, Source | BCL2-antagonist/killer 1 | 5281 | 0.013 | -0.2318 | No |
| 9 | DAP | DAP Entrez, Source | death-associated protein | 5538 | 0.010 | -0.2465 | No |
| 10 | BCL2L2 | BCL2L2 Entrez, Source | BCL2-like 2 | 6379 | 0.000 | -0.3094 | No |
| 11 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 6812 | -0.004 | -0.3402 | No |
| 12 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 6874 | -0.004 | -0.3427 | No |
| 13 | TFPT | TFPT Entrez, Source | TCF3 (E2A) fusion partner (in childhood Leukemia) | 6875 | -0.004 | -0.3406 | No |
| 14 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 7301 | -0.009 | -0.3686 | No |
| 15 | BIK | BIK Entrez, Source | BCL2-interacting killer (apoptosis-inducing) | 7352 | -0.009 | -0.3681 | No |
| 16 | BFAR | BFAR Entrez, Source | bifunctional apoptosis regulator | 7706 | -0.013 | -0.3888 | No |
| 17 | BAX | BAX Entrez, Source | BCL2-associated X protein | 7784 | -0.013 | -0.3883 | No |
| 18 | CASP7 | CASP7 Entrez, Source | caspase 7, apoptosis-related cysteine peptidase | 8153 | -0.017 | -0.4080 | No |
| 19 | BNIP1 | BNIP1 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 1 | 8155 | -0.017 | -0.4001 | No |
| 20 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 8457 | -0.020 | -0.4133 | No |
| 21 | MYD88 | MYD88 Entrez, Source | myeloid differentiation primary response gene (88) | 8694 | -0.023 | -0.4204 | Yes |
| 22 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 8779 | -0.024 | -0.4157 | Yes |
| 23 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 8916 | -0.025 | -0.4142 | Yes |
| 24 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 9040 | -0.026 | -0.4111 | Yes |
| 25 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 9198 | -0.028 | -0.4098 | Yes |
| 26 | BAD | BAD Entrez, Source | BCL2-antagonist of cell death | 9214 | -0.028 | -0.3978 | Yes |
| 27 | DAP3 | DAP3 Entrez, Source | death associated protein 3 | 9414 | -0.030 | -0.3986 | Yes |
| 28 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 9475 | -0.031 | -0.3886 | Yes |
| 29 | DAPK3 | DAPK3 Entrez, Source | death-associated protein kinase 3 | 9914 | -0.036 | -0.4047 | Yes |
| 30 | BAG4 | BAG4 Entrez, Source | BCL2-associated athanogene 4 | 10207 | -0.040 | -0.4082 | Yes |
| 31 | NME3 | NME3 Entrez, Source | non-metastatic cells 3, protein expressed in | 10266 | -0.040 | -0.3938 | Yes |
| 32 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 10368 | -0.041 | -0.3821 | Yes |
| 33 | MAX | MAX Entrez, Source | MYC associated factor X | 10440 | -0.042 | -0.3676 | Yes |
| 34 | BCL2A1 | BCL2A1 Entrez, Source | BCL2-related protein A1 | 10553 | -0.044 | -0.3555 | Yes |
| 35 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 10649 | -0.045 | -0.3414 | Yes |
| 36 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 11474 | -0.060 | -0.3754 | Yes |
| 37 | CFLAR | CFLAR Entrez, Source | CASP8 and FADD-like apoptosis regulator | 11917 | -0.070 | -0.3759 | Yes |
| 38 | BID | BID Entrez, Source | BH3 interacting domain death agonist | 12134 | -0.077 | -0.3562 | Yes |
| 39 | FADD | FADD Entrez, Source | Fas (TNFRSF6)-associated via death domain | 12156 | -0.078 | -0.3215 | Yes |
| 40 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12178 | -0.079 | -0.2864 | Yes |
| 41 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 12503 | -0.092 | -0.2681 | Yes |
| 42 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 12839 | -0.114 | -0.2401 | Yes |
| 43 | PAWR | PAWR Entrez, Source | PRKC, apoptosis, WT1, regulator | 12871 | -0.118 | -0.1873 | Yes |
| 44 | LTB | LTB Entrez, Source | lymphotoxin beta (TNF superfamily, member 3) | 13250 | -0.220 | -0.1131 | Yes |
| 45 | APAF1 | APAF1 Entrez, Source | apoptotic peptidase activating factor | 13280 | -0.257 | 0.0047 | Yes |
