Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | CANCER_UNDIFFERENTIATED_META_UP |
| Enrichment Score (ES) | -0.5459388 |
| Normalized Enrichment Score (NES) | -1.7705064 |
| Nominal p-value | 0.00407332 |
| FDR q-value | 0.13977915 |
| FWER p-Value | 0.992 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 1122 | 0.086 | -0.0408 | No |
| 2 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 1229 | 0.083 | -0.0071 | No |
| 3 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 3296 | 0.038 | -0.1431 | No |
| 4 | ADRM1 | ADRM1 Entrez, Source | adhesion regulating molecule 1 | 4624 | 0.020 | -0.2325 | No |
| 5 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 4803 | 0.018 | -0.2366 | No |
| 6 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 5083 | 0.015 | -0.2500 | No |
| 7 | FOXM1 | FOXM1 Entrez, Source | forkhead box M1 | 5100 | 0.015 | -0.2437 | No |
| 8 | CTSL | CTSL Entrez, Source | cathepsin L | 6275 | 0.002 | -0.3311 | No |
| 9 | PSMB7 | PSMB7 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 7 | 6692 | -0.003 | -0.3610 | No |
| 10 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 6879 | -0.004 | -0.3727 | No |
| 11 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 6975 | -0.005 | -0.3771 | No |
| 12 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 7114 | -0.007 | -0.3841 | No |
| 13 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 7116 | -0.007 | -0.3807 | No |
| 14 | EIF2S2 | EIF2S2 Entrez, Source | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 7630 | -0.012 | -0.4134 | No |
| 15 | CCT6A | CCT6A Entrez, Source | chaperonin containing TCP1, subunit 6A (zeta 1) | 7874 | -0.014 | -0.4244 | No |
| 16 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 8303 | -0.019 | -0.4471 | No |
| 17 | KPNA2 | KPNA2 Entrez, Source | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 8310 | -0.019 | -0.4381 | No |
| 18 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 8512 | -0.021 | -0.4427 | No |
| 19 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9337 | -0.029 | -0.4898 | No |
| 20 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 10085 | -0.038 | -0.5267 | Yes |
| 21 | SSBP1 | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 10100 | -0.038 | -0.5084 | Yes |
| 22 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 10597 | -0.045 | -0.5231 | Yes |
| 23 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 10666 | -0.046 | -0.5052 | Yes |
| 24 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 10707 | -0.046 | -0.4848 | Yes |
| 25 | NME1 | NME1 Entrez, Source | non-metastatic cells 1, protein (NM23A) expressed in | 10783 | -0.048 | -0.4664 | Yes |
| 26 | CXCL9 | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 10997 | -0.051 | -0.4567 | Yes |
| 27 | TUBB | TUBB Entrez, Source | tubulin, beta | 11384 | -0.058 | -0.4563 | Yes |
| 28 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 11497 | -0.060 | -0.4343 | Yes |
| 29 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 11710 | -0.065 | -0.4175 | Yes |
| 30 | GAS6 | GAS6 Entrez, Source | growth arrest-specific 6 | 11976 | -0.072 | -0.4011 | Yes |
| 31 | NUDT1 | NUDT1 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 11990 | -0.073 | -0.3655 | Yes |
| 32 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12131 | -0.077 | -0.3373 | Yes |
| 33 | TMSB10 | TMSB10 Entrez, Source | thymosin, beta 10 | 12891 | -0.120 | -0.3338 | Yes |
| 34 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 13078 | -0.144 | -0.2750 | Yes |
| 35 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13194 | -0.185 | -0.1904 | Yes |
| 36 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13196 | -0.186 | -0.0966 | Yes |
| 37 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13232 | -0.213 | 0.0083 | Yes |
