Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | CCANNAGRKGGC_UNKNOWN |
| Enrichment Score (ES) | 0.53188604 |
| Normalized Enrichment Score (NES) | 1.8949889 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.04992172 |
| FWER p-Value | 0.748 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 105 | 0.175 | 0.0686 | Yes |
| 2 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 446 | 0.122 | 0.0963 | Yes |
| 3 | SOST | SOST Entrez, Source | sclerosteosis | 449 | 0.122 | 0.1494 | Yes |
| 4 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 569 | 0.112 | 0.1895 | Yes |
| 5 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 655 | 0.107 | 0.2297 | Yes |
| 6 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 900 | 0.095 | 0.2531 | Yes |
| 7 | FBXO16 | FBXO16 Entrez, Source | F-box protein 16 | 1089 | 0.087 | 0.2772 | Yes |
| 8 | SNIP | SNIP Entrez, Source | - | 1237 | 0.082 | 0.3020 | Yes |
| 9 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 1303 | 0.080 | 0.3322 | Yes |
| 10 | POU2F3 | POU2F3 Entrez, Source | POU domain, class 2, transcription factor 3 | 1357 | 0.079 | 0.3625 | Yes |
| 11 | SOX10 | SOX10 Entrez, Source | SRY (sex determining region Y)-box 10 | 1485 | 0.075 | 0.3857 | Yes |
| 12 | GPR37L1 | GPR37L1 Entrez, Source | G protein-coupled receptor 37 like 1 | 1769 | 0.068 | 0.3943 | Yes |
| 13 | GRPR | GRPR Entrez, Source | gastrin-releasing peptide receptor | 1848 | 0.066 | 0.4173 | Yes |
| 14 | OPCML | OPCML Entrez, Source | opioid binding protein/cell adhesion molecule-like | 1988 | 0.063 | 0.4343 | Yes |
| 15 | CHRM1 | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 2092 | 0.060 | 0.4529 | Yes |
| 16 | MB | MB Entrez, Source | myoglobin | 2128 | 0.059 | 0.4762 | Yes |
| 17 | CSF3 | CSF3 Entrez, Source | colony stimulating factor 3 (granulocyte) | 2213 | 0.057 | 0.4949 | Yes |
| 18 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 2228 | 0.057 | 0.5186 | Yes |
| 19 | YY1 | YY1 Entrez, Source | YY1 transcription factor | 2429 | 0.053 | 0.5268 | Yes |
| 20 | SCN3A | SCN3A Entrez, Source | sodium channel, voltage-gated, type III, alpha | 2647 | 0.049 | 0.5319 | Yes |
| 21 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3035 | 0.043 | 0.5214 | No |
| 22 | KAZALD1 | KAZALD1 Entrez, Source | Kazal-type serine peptidase inhibitor domain 1 | 3764 | 0.032 | 0.4804 | No |
| 23 | CNTNAP1 | CNTNAP1 Entrez, Source | contactin associated protein 1 | 4016 | 0.028 | 0.4738 | No |
| 24 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 4143 | 0.026 | 0.4759 | No |
| 25 | PITPNM1 | PITPNM1 Entrez, Source | phosphatidylinositol transfer protein, membrane-associated 1 | 4270 | 0.025 | 0.4774 | No |
| 26 | SLC35E4 | SLC35E4 Entrez, Source | solute carrier family 35, member E4 | 4437 | 0.023 | 0.4748 | No |
| 27 | GAS7 | GAS7 Entrez, Source | growth arrest-specific 7 | 4771 | 0.019 | 0.4580 | No |
| 28 | ADORA1 | ADORA1 Entrez, Source | adenosine A1 receptor | 4876 | 0.018 | 0.4579 | No |
| 29 | SLIT3 | SLIT3 Entrez, Source | slit homolog 3 (Drosophila) | 5054 | 0.015 | 0.4513 | No |
| 30 | ESR2 | ESR2 Entrez, Source | estrogen receptor 2 (ER beta) | 5212 | 0.014 | 0.4454 | No |
| 31 | DGKA | DGKA Entrez, Source | diacylglycerol kinase, alpha 80kDa | 5474 | 0.010 | 0.4304 | No |
| 32 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 5545 | 0.010 | 0.4293 | No |
| 33 | CABP1 | CABP1 Entrez, Source | calcium binding protein 1 (calbrain) | 5653 | 0.008 | 0.4250 | No |
| 34 | ACBD4 | ACBD4 Entrez, Source | acyl-Coenzyme A binding domain containing 4 | 5702 | 0.008 | 0.4248 | No |
| 35 | PUM2 | PUM2 Entrez, Source | pumilio homolog 2 (Drosophila) | 6077 | 0.004 | 0.3984 | No |
| 36 | RPS4X | RPS4X Entrez, Source | ribosomal protein S4, X-linked | 6493 | -0.001 | 0.3675 | No |
| 37 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 6865 | -0.004 | 0.3415 | No |
| 38 | ARF1 | ARF1 Entrez, Source | ADP-ribosylation factor 1 | 7820 | -0.014 | 0.2758 | No |
| 39 | C1QBP | C1QBP Entrez, Source | complement component 1, q subcomponent binding protein | 8371 | -0.019 | 0.2429 | No |
| 40 | GRK5 | GRK5 Entrez, Source | G protein-coupled receptor kinase 5 | 8649 | -0.022 | 0.2318 | No |
| 41 | ALK | ALK Entrez, Source | anaplastic lymphoma kinase (Ki-1) | 8660 | -0.022 | 0.2408 | No |
| 42 | GRN | GRN Entrez, Source | granulin | 8678 | -0.023 | 0.2494 | No |
| 43 | DAPK2 | DAPK2 Entrez, Source | death-associated protein kinase 2 | 9112 | -0.027 | 0.2287 | No |
| 44 | AQP6 | AQP6 Entrez, Source | aquaporin 6, kidney specific | 9826 | -0.035 | 0.1906 | No |
| 45 | CADPS | CADPS Entrez, Source | Ca2+-dependent secretion activator | 10578 | -0.044 | 0.1535 | No |
| 46 | CORIN | CORIN Entrez, Source | corin, serine peptidase | 11117 | -0.053 | 0.1362 | No |
| 47 | NPDC1 | NPDC1 Entrez, Source | neural proliferation, differentiation and control, 1 | 11942 | -0.071 | 0.1053 | No |
