Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | CELL_CYCLE_CHECKPOINT_GO_0000075 |
| Enrichment Score (ES) | -0.52707005 |
| Normalized Enrichment Score (NES) | -1.485687 |
| Nominal p-value | 0.07261411 |
| FDR q-value | 0.28075287 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 763 | 0.101 | 0.0463 | No |
| 2 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 5083 | 0.015 | -0.2625 | No |
| 3 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 5612 | 0.009 | -0.2930 | No |
| 4 | ZW10 | ZW10 Entrez, Source | ZW10, kinetochore associated, homolog (Drosophila) | 6013 | 0.004 | -0.3184 | No |
| 5 | CHFR | CHFR Entrez, Source | checkpoint with forkhead and ring finger domains | 8794 | -0.024 | -0.5027 | Yes |
| 6 | MAD2L2 | MAD2L2 Entrez, Source | MAD2 mitotic arrest deficient-like 2 (yeast) | 8968 | -0.026 | -0.4895 | Yes |
| 7 | ERCC3 | ERCC3 Entrez, Source | excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) | 9037 | -0.026 | -0.4675 | Yes |
| 8 | NBN | NBN Entrez, Source | nibrin | 9071 | -0.027 | -0.4427 | Yes |
| 9 | CHEK2 | CHEK2 Entrez, Source | CHK2 checkpoint homolog (S. pombe) | 9129 | -0.027 | -0.4191 | Yes |
| 10 | SMC1A | SMC1A Entrez, Source | structural maintenance of chromosomes 1A | 9336 | -0.029 | -0.4045 | Yes |
| 11 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 9542 | -0.032 | -0.3872 | Yes |
| 12 | DDB1 | DDB1 Entrez, Source | damage-specific DNA binding protein 1, 127kDa | 10146 | -0.039 | -0.3928 | Yes |
| 13 | ZWINT | ZWINT Entrez, Source | ZW10 interactor | 10978 | -0.051 | -0.4033 | Yes |
| 14 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 12350 | -0.085 | -0.4191 | Yes |
| 15 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 12364 | -0.086 | -0.3324 | Yes |
| 16 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 12607 | -0.097 | -0.2513 | Yes |
| 17 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12847 | -0.115 | -0.1521 | Yes |
| 18 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13194 | -0.185 | 0.0111 | Yes |
