Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | CELL_PROJECTION |
| Enrichment Score (ES) | -0.41496867 |
| Normalized Enrichment Score (NES) | -1.5456842 |
| Nominal p-value | 0.018556701 |
| FDR q-value | 0.26291966 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDK5R1 | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 630 | 0.108 | -0.0168 | No |
| 2 | NEFH | NEFH Entrez, Source | neurofilament, heavy polypeptide 200kDa | 1031 | 0.090 | -0.0214 | No |
| 3 | EVL | EVL Entrez, Source | Enah/Vasp-like | 1214 | 0.083 | -0.0117 | No |
| 4 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 1548 | 0.073 | -0.0160 | No |
| 5 | SYNPO | SYNPO Entrez, Source | synaptopodin | 2217 | 0.057 | -0.0502 | No |
| 6 | ITPR3 | ITPR3 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 3 | 2251 | 0.056 | -0.0368 | No |
| 7 | AKAP4 | AKAP4 Entrez, Source | A kinase (PRKA) anchor protein 4 | 2281 | 0.056 | -0.0233 | No |
| 8 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 2282 | 0.056 | -0.0075 | No |
| 9 | GHRL | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 2417 | 0.053 | -0.0025 | No |
| 10 | ABI3 | ABI3 Entrez, Source | ABI gene family, member 3 | 2584 | 0.050 | -0.0009 | No |
| 11 | CDH23 | CDH23 Entrez, Source | cadherin-like 23 | 2732 | 0.047 | 0.0014 | No |
| 12 | ESPN | ESPN Entrez, Source | espin | 3000 | 0.043 | -0.0066 | No |
| 13 | PIB5PA | PIB5PA Entrez, Source | phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A | 3072 | 0.042 | -0.0001 | No |
| 14 | SLC22A12 | SLC22A12 Entrez, Source | solute carrier family 22 (organic anion/cation transporter), member 12 | 3399 | 0.037 | -0.0143 | No |
| 15 | APBB1 | APBB1 Entrez, Source | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 3442 | 0.036 | -0.0073 | No |
| 16 | CACNA1A | CACNA1A Entrez, Source | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 3570 | 0.034 | -0.0071 | No |
| 17 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 3801 | 0.031 | -0.0157 | No |
| 18 | FGD4 | FGD4 Entrez, Source | FYVE, RhoGEF and PH domain containing 4 | 4227 | 0.026 | -0.0405 | No |
| 19 | ARFIP2 | ARFIP2 Entrez, Source | ADP-ribosylation factor interacting protein 2 (arfaptin 2) | 4256 | 0.025 | -0.0355 | No |
| 20 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 4433 | 0.023 | -0.0423 | No |
| 21 | DNALI1 | DNALI1 Entrez, Source | dynein, axonemal, light intermediate chain 1 | 4753 | 0.019 | -0.0609 | No |
| 22 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 4935 | 0.017 | -0.0698 | No |
| 23 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 5461 | 0.011 | -0.1063 | No |
| 24 | PDPN | PDPN Entrez, Source | podoplanin | 5603 | 0.009 | -0.1144 | No |
| 25 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6594 | -0.002 | -0.1884 | No |
| 26 | DFNB31 | DFNB31 Entrez, Source | deafness, autosomal recessive 31 | 6684 | -0.003 | -0.1943 | No |
| 27 | GAS8 | GAS8 Entrez, Source | growth arrest-specific 8 | 6906 | -0.005 | -0.2097 | No |
| 28 | S100B | S100B Entrez, Source | S100 calcium binding protein B | 6931 | -0.005 | -0.2101 | No |
| 29 | ABI1 | ABI1 Entrez, Source | abl-interactor 1 | 7128 | -0.007 | -0.2229 | No |
| 30 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7350 | -0.009 | -0.2370 | No |
| 31 | USH1C | USH1C Entrez, Source | Usher syndrome 1C (autosomal recessive, severe) | 7369 | -0.009 | -0.2357 | No |
| 32 | FGD1 | FGD1 Entrez, Source | FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia) | 7404 | -0.010 | -0.2356 | No |
| 33 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 7724 | -0.013 | -0.2560 | No |
| 34 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 7869 | -0.014 | -0.2628 | No |
| 35 | GHSR | GHSR Entrez, Source | growth hormone secretagogue receptor | 8118 | -0.017 | -0.2767 | No |
| 36 | NME2 | NME2 Entrez, Source | non-metastatic cells 2, protein (NM23B) expressed in | 8212 | -0.018 | -0.2787 | No |
| 37 | CLIC5 | CLIC5 Entrez, Source | chloride intracellular channel 5 | 8412 | -0.020 | -0.2881 | No |
| 38 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 8579 | -0.022 | -0.2945 | No |
| 39 | TBC1D10A | TBC1D10A Entrez, Source | TBC1 domain family, member 10A | 8967 | -0.026 | -0.3164 | No |
| 40 | TLN1 | TLN1 Entrez, Source | talin 1 | 9094 | -0.027 | -0.3183 | No |
| 41 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 9381 | -0.030 | -0.3314 | No |
| 42 | CTTN | CTTN Entrez, Source | cortactin | 9710 | -0.034 | -0.3464 | No |
| 43 | DTNBP1 | DTNBP1 Entrez, Source | dystrobrevin binding protein 1 | 9855 | -0.036 | -0.3472 | No |
| 44 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 10506 | -0.044 | -0.3839 | No |
| 45 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 10920 | -0.050 | -0.4009 | Yes |
| 46 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11016 | -0.051 | -0.3936 | Yes |
| 47 | DBNL | DBNL Entrez, Source | drebrin-like | 11131 | -0.054 | -0.3870 | Yes |
| 48 | PPT1 | PPT1 Entrez, Source | palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) | 11303 | -0.057 | -0.3838 | Yes |
| 49 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11323 | -0.057 | -0.3691 | Yes |
| 50 | CDH13 | CDH13 Entrez, Source | cadherin 13, H-cadherin (heart) | 11616 | -0.063 | -0.3733 | Yes |
| 51 | SI | SI Entrez, Source | sucrase-isomaltase (alpha-glucosidase) | 11811 | -0.068 | -0.3688 | Yes |
| 52 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 11817 | -0.068 | -0.3500 | Yes |
| 53 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 12392 | -0.087 | -0.3688 | Yes |
| 54 | MYO5A | MYO5A Entrez, Source | myosin VA (heavy chain 12, myoxin) | 12504 | -0.092 | -0.3513 | Yes |
| 55 | CDK5 | CDK5 Entrez, Source | cyclin-dependent kinase 5 | 12840 | -0.114 | -0.3443 | Yes |
| 56 | MYO1C | MYO1C Entrez, Source | myosin IC | 12875 | -0.118 | -0.3134 | Yes |
| 57 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 12923 | -0.123 | -0.2821 | Yes |
| 58 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 13140 | -0.159 | -0.2534 | Yes |
| 59 | CLIC1 | CLIC1 Entrez, Source | chloride intracellular channel 1 | 13242 | -0.218 | -0.1995 | Yes |
| 60 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13295 | -0.275 | -0.1259 | Yes |
| 61 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 13330 | -0.458 | 0.0009 | Yes |
