Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | CHANG_SERUM_RESPONSE_UP |
| Enrichment Score (ES) | -0.45118922 |
| Normalized Enrichment Score (NES) | -1.8221844 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.11420236 |
| FWER p-Value | 0.945 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAP3K8 | MAP3K8 Entrez, Source | mitogen-activated protein kinase kinase kinase 8 | 9 | 0.350 | 0.0552 | No |
| 2 | EMP2 | EMP2 Entrez, Source | epithelial membrane protein 2 | 79 | 0.187 | 0.0798 | No |
| 3 | PLG | PLG Entrez, Source | plasminogen | 229 | 0.144 | 0.0916 | No |
| 4 | CDCA4 | CDCA4 Entrez, Source | cell division cycle associated 4 | 791 | 0.100 | 0.0652 | No |
| 5 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 1229 | 0.083 | 0.0453 | No |
| 6 | HAS2 | HAS2 Entrez, Source | hyaluronan synthase 2 | 1343 | 0.079 | 0.0494 | No |
| 7 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 1387 | 0.078 | 0.0586 | No |
| 8 | DCK | DCK Entrez, Source | deoxycytidine kinase | 1598 | 0.072 | 0.0543 | No |
| 9 | FLNC | FLNC Entrez, Source | filamin C, gamma (actin binding protein 280) | 1809 | 0.067 | 0.0492 | No |
| 10 | MT3 | MT3 Entrez, Source | metallothionein 3 (growth inhibitory factor (neurotrophic)) | 1858 | 0.066 | 0.0561 | No |
| 11 | RNF138 | RNF138 Entrez, Source | ring finger protein 138 | 1949 | 0.064 | 0.0594 | No |
| 12 | SSR3 | SSR3 Entrez, Source | signal sequence receptor, gamma (translocon-associated protein gamma) | 2198 | 0.057 | 0.0499 | No |
| 13 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 2524 | 0.051 | 0.0335 | No |
| 14 | NUP107 | NUP107 Entrez, Source | nucleoporin 107kDa | 3252 | 0.039 | -0.0151 | No |
| 15 | NUPL1 | NUPL1 Entrez, Source | nucleoporin like 1 | 3508 | 0.035 | -0.0288 | No |
| 16 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 3631 | 0.033 | -0.0326 | No |
| 17 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 3869 | 0.030 | -0.0457 | No |
| 18 | SRM | SRM Entrez, Source | spermidine synthase | 4594 | 0.021 | -0.0971 | No |
| 19 | COX17 | COX17 Entrez, Source | COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) | 5087 | 0.015 | -0.1318 | No |
| 20 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 5213 | 0.014 | -0.1391 | No |
| 21 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 5320 | 0.012 | -0.1451 | No |
| 22 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 5816 | 0.007 | -0.1814 | No |
| 23 | GPLD1 | GPLD1 Entrez, Source | glycosylphosphatidylinositol specific phospholipase D1 | 5931 | 0.005 | -0.1892 | No |
| 24 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 6161 | 0.003 | -0.2060 | No |
| 25 | IMP4 | IMP4 Entrez, Source | IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) | 6270 | 0.002 | -0.2139 | No |
| 26 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 6341 | 0.001 | -0.2191 | No |
| 27 | TNFRSF12A | TNFRSF12A Entrez, Source | tumor necrosis factor receptor superfamily, member 12A | 6604 | -0.002 | -0.2385 | No |
| 28 | SLC25A5 | SLC25A5 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 6656 | -0.003 | -0.2420 | No |
| 29 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 6753 | -0.003 | -0.2487 | No |
| 30 | SNRPA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 6866 | -0.004 | -0.2564 | No |
| 31 | PSMD12 | PSMD12 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 7220 | -0.008 | -0.2818 | No |
| 32 | EBNA1BP2 | EBNA1BP2 Entrez, Source | EBNA1 binding protein 2 | 7242 | -0.008 | -0.2821 | No |
| 33 | EIF4EBP1 | EIF4EBP1 Entrez, Source | eukaryotic translation initiation factor 4E binding protein 1 | 7338 | -0.009 | -0.2879 | No |
| 34 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 7387 | -0.009 | -0.2900 | No |
| 35 | LYAR | LYAR Entrez, Source | - | 7434 | -0.010 | -0.2919 | No |
| 36 | CENPJ | CENPJ Entrez, Source | centromere protein J | 7469 | -0.010 | -0.2928 | No |
| 37 | TCEB1 | TCEB1 Entrez, Source | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 7679 | -0.012 | -0.3067 | No |
| 38 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 7800 | -0.014 | -0.3136 | No |
| 39 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 8088 | -0.017 | -0.3326 | No |
| 40 | HMGB1 | HMGB1 Entrez, Source | high-mobility group box 1 | 8126 | -0.017 | -0.3327 | No |
| 41 | RPN1 | RPN1 Entrez, Source | ribophorin I | 8214 | -0.018 | -0.3364 | No |
| 42 | RUVBL1 | RUVBL1 Entrez, Source | RuvB-like 1 (E. coli) | 8268 | -0.018 | -0.3374 | No |
| 43 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 8391 | -0.020 | -0.3435 | No |
| 44 | PFN1 | PFN1 Entrez, Source | profilin 1 | 8402 | -0.020 | -0.3412 | No |
| 45 | VDAC1 | VDAC1 Entrez, Source | voltage-dependent anion channel 1 | 8435 | -0.020 | -0.3404 | No |
| 46 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 8512 | -0.021 | -0.3428 | No |
| 47 | MAPRE1 | MAPRE1 Entrez, Source | microtubule-associated protein, RP/EB family, member 1 | 8516 | -0.021 | -0.3397 | No |
| 48 | RNF41 | RNF41 Entrez, Source | ring finger protein 41 | 8665 | -0.022 | -0.3473 | No |
| 49 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 8745 | -0.023 | -0.3495 | No |
| 50 | TOMM40 | TOMM40 Entrez, Source | translocase of outer mitochondrial membrane 40 homolog (yeast) | 8940 | -0.025 | -0.3601 | No |
| 51 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 8949 | -0.025 | -0.3567 | No |
| 52 | PDAP1 | PDAP1 Entrez, Source | PDGFA associated protein 1 | 8993 | -0.026 | -0.3558 | No |
| 53 | TXNL2 | TXNL2 Entrez, Source | thioredoxin-like 2 | 9021 | -0.026 | -0.3536 | No |
| 54 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 9329 | -0.029 | -0.3721 | No |
| 55 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 9334 | -0.029 | -0.3677 | No |
| 56 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 9409 | -0.030 | -0.3685 | No |
| 57 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 9616 | -0.033 | -0.3788 | No |
| 58 | PSMA7 | PSMA7 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 7 | 9751 | -0.034 | -0.3834 | No |
| 59 | RNASEH2A | RNASEH2A Entrez, Source | ribonuclease H2, subunit A | 10032 | -0.037 | -0.3985 | No |
| 60 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 10063 | -0.038 | -0.3948 | No |
| 61 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 10244 | -0.040 | -0.4020 | No |
| 62 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 10352 | -0.041 | -0.4035 | No |
| 63 | MRPL37 | MRPL37 Entrez, Source | mitochondrial ribosomal protein L37 | 10420 | -0.042 | -0.4018 | No |
| 64 | MRPL12 | MRPL12 Entrez, Source | mitochondrial ribosomal protein L12 | 10545 | -0.044 | -0.4041 | No |
| 65 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 10597 | -0.045 | -0.4009 | No |
| 66 | NME1 | NME1 Entrez, Source | non-metastatic cells 1, protein (NM23A) expressed in | 10783 | -0.048 | -0.4072 | No |
| 67 | MKKS | MKKS Entrez, Source | McKusick-Kaufman syndrome | 10791 | -0.048 | -0.4001 | No |
| 68 | PCSK7 | PCSK7 Entrez, Source | proprotein convertase subtilisin/kexin type 7 | 10794 | -0.048 | -0.3926 | No |
| 69 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 10811 | -0.048 | -0.3862 | No |
| 70 | DCLRE1B | DCLRE1B Entrez, Source | DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae) | 10917 | -0.050 | -0.3861 | No |
| 71 | GNG11 | GNG11 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 11 | 11142 | -0.054 | -0.3945 | No |
| 72 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 11374 | -0.058 | -0.4026 | No |
| 73 | NLN | NLN Entrez, Source | neurolysin (metallopeptidase M3 family) | 11920 | -0.070 | -0.4325 | No |
| 74 | NUDT1 | NUDT1 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 11990 | -0.073 | -0.4262 | No |
| 75 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12131 | -0.077 | -0.4245 | No |
| 76 | TUBG1 | TUBG1 Entrez, Source | tubulin, gamma 1 | 12486 | -0.090 | -0.4368 | Yes |
| 77 | CKLF | CKLF Entrez, Source | chemokine-like factor | 12527 | -0.093 | -0.4250 | Yes |
| 78 | WSB2 | WSB2 Entrez, Source | WD repeat and SOCS box-containing 2 | 12797 | -0.110 | -0.4277 | Yes |
| 79 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12847 | -0.115 | -0.4131 | Yes |
| 80 | SMS | SMS Entrez, Source | spermine synthase | 12884 | -0.119 | -0.3968 | Yes |
| 81 | PTS | PTS Entrez, Source | 6-pyruvoyltetrahydropterin synthase | 12892 | -0.120 | -0.3782 | Yes |
| 82 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12915 | -0.123 | -0.3602 | Yes |
| 83 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12937 | -0.125 | -0.3418 | Yes |
| 84 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 13021 | -0.135 | -0.3266 | Yes |
| 85 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 13084 | -0.146 | -0.3079 | Yes |
| 86 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 13148 | -0.161 | -0.2871 | Yes |
| 87 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 13167 | -0.169 | -0.2615 | Yes |
| 88 | ADAMTS1 | ADAMTS1 Entrez, Source | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 13169 | -0.170 | -0.2345 | Yes |
| 89 | MSN | MSN Entrez, Source | moesin | 13233 | -0.213 | -0.2052 | Yes |
| 90 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13312 | -0.331 | -0.1584 | Yes |
| 91 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13314 | -0.341 | -0.1042 | Yes |
| 92 | TAGLN | TAGLN Entrez, Source | transgelin | 13340 | -0.666 | 0.0002 | Yes |
