Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | CYTOKINE_BINDING |
| Enrichment Score (ES) | 0.47773668 |
| Normalized Enrichment Score (NES) | 1.5532516 |
| Nominal p-value | 0.024667932 |
| FDR q-value | 0.23162158 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | A2M | A2M Entrez, Source | alpha-2-macroglobulin | 167 | 0.155 | 0.0713 | Yes |
| 2 | IL8RA | IL8RA Entrez, Source | interleukin 8 receptor, alpha | 228 | 0.145 | 0.1449 | Yes |
| 3 | IL17F | IL17F Entrez, Source | interleukin 17F | 522 | 0.115 | 0.1851 | Yes |
| 4 | IL6R | IL6R Entrez, Source | interleukin 6 receptor | 695 | 0.104 | 0.2286 | Yes |
| 5 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 716 | 0.103 | 0.2829 | Yes |
| 6 | IL9R | IL9R Entrez, Source | interleukin 9 receptor | 1094 | 0.087 | 0.3017 | Yes |
| 7 | IL8RB | IL8RB Entrez, Source | interleukin 8 receptor, beta | 1170 | 0.085 | 0.3419 | Yes |
| 8 | TNFRSF14 | TNFRSF14 Entrez, Source | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 1175 | 0.085 | 0.3874 | Yes |
| 9 | CMKLR1 | CMKLR1 Entrez, Source | chemokine-like receptor 1 | 1681 | 0.070 | 0.3875 | Yes |
| 10 | IL12RB2 | IL12RB2 Entrez, Source | interleukin 12 receptor, beta 2 | 1853 | 0.066 | 0.4103 | Yes |
| 11 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 2130 | 0.059 | 0.4217 | Yes |
| 12 | IL5RA | IL5RA Entrez, Source | interleukin 5 receptor, alpha | 2604 | 0.050 | 0.4130 | Yes |
| 13 | TNFRSF4 | TNFRSF4 Entrez, Source | tumor necrosis factor receptor superfamily, member 4 | 2639 | 0.049 | 0.4370 | Yes |
| 14 | ACVRL1 | ACVRL1 Entrez, Source | activin A receptor type II-like 1 | 2800 | 0.046 | 0.4499 | Yes |
| 15 | IL13RA2 | IL13RA2 Entrez, Source | interleukin 13 receptor, alpha 2 | 2962 | 0.044 | 0.4614 | Yes |
| 16 | IL2RB | IL2RB Entrez, Source | interleukin 2 receptor, beta | 3050 | 0.042 | 0.4777 | Yes |
| 17 | IL10RA | IL10RA Entrez, Source | interleukin 10 receptor, alpha | 3942 | 0.029 | 0.4266 | No |
| 18 | CNTFR | CNTFR Entrez, Source | ciliary neurotrophic factor receptor | 4004 | 0.028 | 0.4373 | No |
| 19 | IL2RA | IL2RA Entrez, Source | interleukin 2 receptor, alpha | 4057 | 0.028 | 0.4483 | No |
| 20 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 4100 | 0.027 | 0.4598 | No |
| 21 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 5475 | 0.010 | 0.3622 | No |
| 22 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 5860 | 0.006 | 0.3365 | No |
| 23 | IL18BP | IL18BP Entrez, Source | interleukin 18 binding protein | 6672 | -0.003 | 0.2771 | No |
| 24 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 7360 | -0.009 | 0.2304 | No |
| 25 | TGFBR1 | TGFBR1 Entrez, Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 7514 | -0.011 | 0.2246 | No |
| 26 | IL3RA | IL3RA Entrez, Source | interleukin 3 receptor, alpha (low affinity) | 9102 | -0.027 | 0.1200 | No |
| 27 | IL6ST | IL6ST Entrez, Source | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 9951 | -0.037 | 0.0761 | No |
| 28 | IL22RA2 | IL22RA2 Entrez, Source | interleukin 22 receptor, alpha 2 | 11846 | -0.069 | -0.0291 | No |
| 29 | IL12A | IL12A Entrez, Source | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 12062 | -0.075 | -0.0049 | No |
| 30 | IFNGR1 | IFNGR1 Entrez, Source | interferon gamma receptor 1 | 12154 | -0.078 | 0.0303 | No |
| 31 | IL2RG | IL2RG Entrez, Source | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 12775 | -0.109 | 0.0426 | No |
