Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | CYTOSKELETAL_PART |
| Enrichment Score (ES) | -0.3966474 |
| Normalized Enrichment Score (NES) | -1.646173 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.19539973 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SPTBN4 | SPTBN4 Entrez, Source | spectrin, beta, non-erythrocytic 4 | 71 | 0.192 | 0.0263 | No |
| 2 | CETN1 | CETN1 Entrez, Source | centrin, EF-hand protein, 1 | 364 | 0.129 | 0.0254 | No |
| 3 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 441 | 0.122 | 0.0398 | No |
| 4 | TNNI3 | TNNI3 Entrez, Source | troponin I type 3 (cardiac) | 617 | 0.109 | 0.0445 | No |
| 5 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 731 | 0.103 | 0.0529 | No |
| 6 | KIF5A | KIF5A Entrez, Source | kinesin family member 5A | 1145 | 0.086 | 0.0359 | No |
| 7 | KIF4A | KIF4A Entrez, Source | kinesin family member 4A | 1522 | 0.074 | 0.0196 | No |
| 8 | CACNA1C | CACNA1C Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1C subunit | 1939 | 0.064 | -0.0013 | No |
| 9 | MYH7 | MYH7 Entrez, Source | myosin, heavy chain 7, cardiac muscle, beta | 2024 | 0.062 | 0.0026 | No |
| 10 | MYL3 | MYL3 Entrez, Source | myosin, light chain 3, alkali; ventricular, skeletal, slow | 2080 | 0.061 | 0.0084 | No |
| 11 | CEP57 | CEP57 Entrez, Source | centrosomal protein 57kDa | 2503 | 0.052 | -0.0150 | No |
| 12 | GFAP | GFAP Entrez, Source | glial fibrillary acidic protein | 2549 | 0.051 | -0.0101 | No |
| 13 | NARF | NARF Entrez, Source | nuclear prelamin A recognition factor | 2832 | 0.046 | -0.0239 | No |
| 14 | ESPN | ESPN Entrez, Source | espin | 3000 | 0.043 | -0.0294 | No |
| 15 | DCX | DCX Entrez, Source | doublecortex; lissencephaly, X-linked (doublecortin) | 3092 | 0.042 | -0.0294 | No |
| 16 | MAP1B | MAP1B Entrez, Source | microtubule-associated protein 1B | 3700 | 0.033 | -0.0699 | No |
| 17 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 3835 | 0.031 | -0.0750 | No |
| 18 | BMF | BMF Entrez, Source | Bcl2 modifying factor | 4020 | 0.028 | -0.0843 | No |
| 19 | DRD2 | DRD2 Entrez, Source | dopamine receptor D2 | 4082 | 0.027 | -0.0844 | No |
| 20 | KATNA1 | KATNA1 Entrez, Source | katanin p60 (ATPase-containing) subunit A 1 | 4394 | 0.023 | -0.1041 | No |
| 21 | MYH6 | MYH6 Entrez, Source | myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) | 4670 | 0.020 | -0.1216 | No |
| 22 | DNALI1 | DNALI1 Entrez, Source | dynein, axonemal, light intermediate chain 1 | 4753 | 0.019 | -0.1247 | No |
| 23 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 5083 | 0.015 | -0.1470 | No |
| 24 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 5213 | 0.014 | -0.1546 | No |
| 25 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 5222 | 0.013 | -0.1529 | No |
| 26 | KIFC3 | KIFC3 Entrez, Source | kinesin family member C3 | 5345 | 0.012 | -0.1602 | No |
| 27 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 5461 | 0.011 | -0.1671 | No |
| 28 | TPT1 | TPT1 Entrez, Source | tumor protein, translationally-controlled 1 | 5480 | 0.010 | -0.1668 | No |
| 29 | MEFV | MEFV Entrez, Source | Mediterranean fever | 5582 | 0.009 | -0.1729 | No |
| 30 | CABP1 | CABP1 Entrez, Source | calcium binding protein 1 (calbrain) | 5653 | 0.008 | -0.1768 | No |
| 31 | ZW10 | ZW10 Entrez, Source | ZW10, kinetochore associated, homolog (Drosophila) | 6013 | 0.004 | -0.2032 | No |
| 32 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 6305 | 0.001 | -0.2250 | No |
| 33 | DYNC1I1 | DYNC1I1 Entrez, Source | dynein, cytoplasmic 1, intermediate chain 1 | 6548 | -0.001 | -0.2430 | No |
| 34 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 6569 | -0.002 | -0.2443 | No |
| 35 | TUBGCP3 | TUBGCP3 Entrez, Source | tubulin, gamma complex associated protein 3 | 6657 | -0.003 | -0.2504 | No |
| 36 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 6701 | -0.003 | -0.2532 | No |
| 37 | SEPT9 | SEPT9 Entrez, Source | septin 9 | 6891 | -0.005 | -0.2667 | No |
| 38 | GAS8 | GAS8 Entrez, Source | growth arrest-specific 8 | 6906 | -0.005 | -0.2670 | No |
| 39 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 6975 | -0.005 | -0.2713 | No |
| 40 | ATG4B | ATG4B Entrez, Source | ATG4 autophagy related 4 homolog B (S. cerevisiae) | 7075 | -0.006 | -0.2777 | No |
| 41 | HDAC6 | HDAC6 Entrez, Source | histone deacetylase 6 | 7465 | -0.010 | -0.3054 | No |
| 42 | SEPT7 | SEPT7 Entrez, Source | septin 7 | 7594 | -0.011 | -0.3132 | No |
| 43 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 7724 | -0.013 | -0.3209 | No |
| 44 | NEDD9 | NEDD9 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 9 | 7794 | -0.013 | -0.3238 | No |
| 45 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 7818 | -0.014 | -0.3233 | No |
| 46 | CAPZA2 | CAPZA2 Entrez, Source | capping protein (actin filament) muscle Z-line, alpha 2 | 8236 | -0.018 | -0.3518 | No |
| 47 | TBCE | TBCE Entrez, Source | tubulin-specific chaperone e | 8239 | -0.018 | -0.3490 | No |
| 48 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 8248 | -0.018 | -0.3466 | No |
| 49 | SIRT2 | SIRT2 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) | 8333 | -0.019 | -0.3498 | No |
| 50 | MAPRE1 | MAPRE1 Entrez, Source | microtubule-associated protein, RP/EB family, member 1 | 8516 | -0.021 | -0.3601 | No |
| 51 | STAU1 | STAU1 Entrez, Source | staufen, RNA binding protein, homolog 1 (Drosophila) | 8520 | -0.021 | -0.3569 | No |
| 52 | KIF3C | KIF3C Entrez, Source | kinesin family member 3C | 8551 | -0.021 | -0.3557 | No |
| 53 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 8579 | -0.022 | -0.3542 | No |
| 54 | DYNLL2 | DYNLL2 Entrez, Source | dynein, light chain, LC8-type 2 | 8613 | -0.022 | -0.3530 | No |
| 55 | CDC16 | CDC16 Entrez, Source | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 8614 | -0.022 | -0.3494 | No |
| 56 | ACTR2 | ACTR2 Entrez, Source | ARP2 actin-related protein 2 homolog (yeast) | 8777 | -0.024 | -0.3578 | No |
| 57 | MYO9B | MYO9B Entrez, Source | myosin IXB | 8864 | -0.025 | -0.3602 | No |
| 58 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 8948 | -0.025 | -0.3623 | No |
| 59 | ACTR1B | ACTR1B Entrez, Source | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | 9228 | -0.028 | -0.3787 | No |
| 60 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 9302 | -0.029 | -0.3794 | No |
| 61 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9337 | -0.029 | -0.3772 | No |
| 62 | POLB | POLB Entrez, Source | polymerase (DNA directed), beta | 9596 | -0.033 | -0.3913 | Yes |
| 63 | TSGA14 | TSGA14 Entrez, Source | testis specific, 14 | 9628 | -0.033 | -0.3882 | Yes |
| 64 | AURKA | AURKA Entrez, Source | aurora kinase A | 9667 | -0.034 | -0.3855 | Yes |
| 65 | ARHGEF2 | ARHGEF2 Entrez, Source | rho/rac guanine nucleotide exchange factor (GEF) 2 | 9794 | -0.035 | -0.3892 | Yes |
| 66 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 9840 | -0.036 | -0.3868 | Yes |
| 67 | APPBP2 | APPBP2 Entrez, Source | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 9965 | -0.037 | -0.3901 | Yes |
| 68 | CETN3 | CETN3 Entrez, Source | centrin, EF-hand protein, 3 (CDC31 homolog, yeast) | 10040 | -0.038 | -0.3895 | Yes |
| 69 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 10044 | -0.038 | -0.3835 | Yes |
| 70 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 10085 | -0.038 | -0.3802 | Yes |
| 71 | GYS2 | GYS2 Entrez, Source | glycogen synthase 2 (liver) | 10212 | -0.040 | -0.3832 | Yes |
| 72 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 10216 | -0.040 | -0.3769 | Yes |
| 73 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 10273 | -0.040 | -0.3745 | Yes |
| 74 | SMC3 | SMC3 Entrez, Source | structural maintenance of chromosomes 3 | 10429 | -0.042 | -0.3793 | Yes |
| 75 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 10506 | -0.044 | -0.3778 | Yes |
| 76 | DCTN2 | DCTN2 Entrez, Source | dynactin 2 (p50) | 10509 | -0.044 | -0.3708 | Yes |
| 77 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 10631 | -0.045 | -0.3725 | Yes |
| 78 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 10717 | -0.047 | -0.3713 | Yes |
| 79 | CKAP5 | CKAP5 Entrez, Source | cytoskeleton associated protein 5 | 10786 | -0.048 | -0.3685 | Yes |
| 80 | ARPC1B | ARPC1B Entrez, Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 10805 | -0.048 | -0.3620 | Yes |
| 81 | CDK5RAP2 | CDK5RAP2 Entrez, Source | CDK5 regulatory subunit associated protein 2 | 10892 | -0.050 | -0.3603 | Yes |
| 82 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 10920 | -0.050 | -0.3541 | Yes |
| 83 | CAPZB | CAPZB Entrez, Source | capping protein (actin filament) muscle Z-line, beta | 11020 | -0.051 | -0.3532 | Yes |
| 84 | DCTN1 | DCTN1 Entrez, Source | dynactin 1 (p150, glued homolog, Drosophila) | 11141 | -0.054 | -0.3534 | Yes |
| 85 | NDE1 | NDE1 Entrez, Source | nudE nuclear distribution gene E homolog 1 (A. nidulans) | 11233 | -0.056 | -0.3511 | Yes |
| 86 | KATNB1 | KATNB1 Entrez, Source | katanin p80 (WD repeat containing) subunit B 1 | 11300 | -0.057 | -0.3467 | Yes |
| 87 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 11304 | -0.057 | -0.3376 | Yes |
| 88 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11323 | -0.057 | -0.3295 | Yes |
| 89 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 11447 | -0.059 | -0.3290 | Yes |
| 90 | MYOM1 | MYOM1 Entrez, Source | myomesin 1 (skelemin) 185kDa | 11511 | -0.061 | -0.3237 | Yes |
| 91 | CDC27 | CDC27 Entrez, Source | cell division cycle 27 | 11606 | -0.063 | -0.3205 | Yes |
| 92 | KIF5B | KIF5B Entrez, Source | kinesin family member 5B | 11786 | -0.067 | -0.3230 | Yes |
| 93 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 11925 | -0.070 | -0.3218 | Yes |
| 94 | ACTC1 | ACTC1 Entrez, Source | actin, alpha, cardiac muscle 1 | 11932 | -0.071 | -0.3106 | Yes |
| 95 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 11968 | -0.072 | -0.3014 | Yes |
| 96 | PCM1 | PCM1 Entrez, Source | pericentriolar material 1 | 12064 | -0.075 | -0.2963 | Yes |
| 97 | APC | APC Entrez, Source | adenomatosis polyposis coli | 12071 | -0.075 | -0.2844 | Yes |
| 98 | VIM | VIM Entrez, Source | vimentin | 12125 | -0.077 | -0.2757 | Yes |
| 99 | PXN | PXN Entrez, Source | paxillin | 12322 | -0.084 | -0.2768 | Yes |
| 100 | TUBG1 | TUBG1 Entrez, Source | tubulin, gamma 1 | 12486 | -0.090 | -0.2742 | Yes |
| 101 | DYNC1LI2 | DYNC1LI2 Entrez, Source | dynein, cytoplasmic 1, light intermediate chain 2 | 12827 | -0.113 | -0.2813 | Yes |
| 102 | MYO1C | MYO1C Entrez, Source | myosin IC | 12875 | -0.118 | -0.2653 | Yes |
| 103 | AKAP9 | AKAP9 Entrez, Source | A kinase (PRKA) anchor protein (yotiao) 9 | 12906 | -0.122 | -0.2475 | Yes |
| 104 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12937 | -0.125 | -0.2292 | Yes |
| 105 | TPM4 | TPM4 Entrez, Source | tropomyosin 4 | 12972 | -0.128 | -0.2106 | Yes |
| 106 | CLASP1 | CLASP1 Entrez, Source | cytoplasmic linker associated protein 1 | 13168 | -0.170 | -0.1974 | Yes |
| 107 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 13185 | -0.179 | -0.1692 | Yes |
| 108 | EML2 | EML2 Entrez, Source | echinoderm microtubule associated protein like 2 | 13203 | -0.193 | -0.1386 | Yes |
| 109 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -0.905 | -0.0000 | Yes |
