Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | CYTOSKELETAL_PROTEIN_BINDING |
| Enrichment Score (ES) | -0.45645824 |
| Normalized Enrichment Score (NES) | -1.8034376 |
| Nominal p-value | 0.0019762847 |
| FDR q-value | 0.12495611 |
| FWER p-Value | 0.97 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SPTBN4 | SPTBN4 Entrez, Source | spectrin, beta, non-erythrocytic 4 | 71 | 0.192 | 0.0294 | No |
| 2 | TTN | TTN Entrez, Source | titin | 262 | 0.140 | 0.0404 | No |
| 3 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 441 | 0.122 | 0.0491 | No |
| 4 | TNNI3 | TNNI3 Entrez, Source | troponin I type 3 (cardiac) | 617 | 0.109 | 0.0557 | No |
| 5 | ABRA | ABRA Entrez, Source | actin-binding Rho activating protein | 657 | 0.107 | 0.0721 | No |
| 6 | SCIN | SCIN Entrez, Source | scinderin | 1542 | 0.074 | 0.0187 | No |
| 7 | ADD2 | ADD2 Entrez, Source | adducin 2 (beta) | 2168 | 0.058 | -0.0179 | No |
| 8 | SYNPO | SYNPO Entrez, Source | synaptopodin | 2217 | 0.057 | -0.0112 | No |
| 9 | RHCG | RHCG Entrez, Source | Rh family, C glycoprotein | 2452 | 0.053 | -0.0193 | No |
| 10 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2716 | 0.048 | -0.0305 | No |
| 11 | JUP | JUP Entrez, Source | junction plakoglobin | 2926 | 0.044 | -0.0383 | No |
| 12 | ESPN | ESPN Entrez, Source | espin | 3000 | 0.043 | -0.0360 | No |
| 13 | HPCA | HPCA Entrez, Source | hippocalcin | 3042 | 0.042 | -0.0314 | No |
| 14 | DCX | DCX Entrez, Source | doublecortex; lissencephaly, X-linked (doublecortin) | 3092 | 0.042 | -0.0276 | No |
| 15 | RHAG | RHAG Entrez, Source | Rh-associated glycoprotein | 3123 | 0.041 | -0.0223 | No |
| 16 | MYBPC1 | MYBPC1 Entrez, Source | myosin binding protein C, slow type | 3531 | 0.035 | -0.0467 | No |
| 17 | SYNE1 | SYNE1 Entrez, Source | spectrin repeat containing, nuclear envelope 1 | 3800 | 0.031 | -0.0613 | No |
| 18 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 3835 | 0.031 | -0.0584 | No |
| 19 | KATNA1 | KATNA1 Entrez, Source | katanin p60 (ATPase-containing) subunit A 1 | 4394 | 0.023 | -0.0962 | No |
| 20 | TMOD2 | TMOD2 Entrez, Source | tropomodulin 2 (neuronal) | 4430 | 0.023 | -0.0947 | No |
| 21 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 4433 | 0.023 | -0.0907 | No |
| 22 | CCR5 | CCR5 Entrez, Source | chemokine (C-C motif) receptor 5 | 4484 | 0.022 | -0.0905 | No |
| 23 | GABARAP | GABARAP Entrez, Source | GABA(A) receptor-associated protein | 4565 | 0.021 | -0.0927 | No |
| 24 | TARDBP | TARDBP Entrez, Source | TAR DNA binding protein | 4950 | 0.017 | -0.1187 | No |
| 25 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 5083 | 0.015 | -0.1259 | No |
| 26 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 5213 | 0.014 | -0.1332 | No |
| 27 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 5461 | 0.011 | -0.1499 | No |
| 28 | MEFV | MEFV Entrez, Source | Mediterranean fever | 5582 | 0.009 | -0.1573 | No |
| 29 | HOOK3 | HOOK3 Entrez, Source | hook homolog 3 (Drosophila) | 5741 | 0.007 | -0.1679 | No |
| 30 | GC | GC Entrez, Source | group-specific component (vitamin D binding protein) | 6045 | 0.004 | -0.1900 | No |
| 31 | SORBS3 | SORBS3 Entrez, Source | sorbin and SH3 domain containing 3 | 6162 | 0.003 | -0.1982 | No |
| 32 | MAPK8IP2 | MAPK8IP2 Entrez, Source | mitogen-activated protein kinase 8 interacting protein 2 | 6319 | 0.001 | -0.2098 | No |
| 33 | MAPK8IP3 | MAPK8IP3 Entrez, Source | mitogen-activated protein kinase 8 interacting protein 3 | 6326 | 0.001 | -0.2101 | No |
| 34 | DYNC1I1 | DYNC1I1 Entrez, Source | dynein, cytoplasmic 1, intermediate chain 1 | 6548 | -0.001 | -0.2265 | No |
| 35 | TUBGCP3 | TUBGCP3 Entrez, Source | tubulin, gamma complex associated protein 3 | 6657 | -0.003 | -0.2342 | No |
| 36 | S100B | S100B Entrez, Source | S100 calcium binding protein B | 6931 | -0.005 | -0.2539 | No |
| 37 | NEXN | NEXN Entrez, Source | nexilin (F actin binding protein) | 6958 | -0.005 | -0.2549 | No |
| 38 | ABI1 | ABI1 Entrez, Source | abl-interactor 1 | 7128 | -0.007 | -0.2664 | No |
| 39 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 7175 | -0.007 | -0.2686 | No |
| 40 | APOE | APOE Entrez, Source | apolipoprotein E | 7282 | -0.008 | -0.2751 | No |
| 41 | LSP1 | LSP1 Entrez, Source | lymphocyte-specific protein 1 | 7298 | -0.009 | -0.2746 | No |
| 42 | CENPJ | CENPJ Entrez, Source | centromere protein J | 7469 | -0.010 | -0.2856 | No |
| 43 | TMOD3 | TMOD3 Entrez, Source | tropomodulin 3 (ubiquitous) | 7774 | -0.013 | -0.3061 | No |
| 44 | GABARAPL2 | GABARAPL2 Entrez, Source | GABA(A) receptor-associated protein-like 2 | 8016 | -0.016 | -0.3215 | No |
| 45 | PACSIN3 | PACSIN3 Entrez, Source | protein kinase C and casein kinase substrate in neurons 3 | 8460 | -0.020 | -0.3512 | No |
| 46 | MAPRE1 | MAPRE1 Entrez, Source | microtubule-associated protein, RP/EB family, member 1 | 8516 | -0.021 | -0.3516 | No |
| 47 | ARPC1A | ARPC1A Entrez, Source | actin related protein 2/3 complex, subunit 1A, 41kDa | 8606 | -0.022 | -0.3544 | No |
| 48 | RPH3AL | RPH3AL Entrez, Source | rabphilin 3A-like (without C2 domains) | 8778 | -0.024 | -0.3630 | No |
| 49 | MYO9B | MYO9B Entrez, Source | myosin IXB | 8864 | -0.025 | -0.3649 | No |
| 50 | TLN1 | TLN1 Entrez, Source | talin 1 | 9094 | -0.027 | -0.3773 | No |
| 51 | DLG1 | DLG1 Entrez, Source | discs, large homolog 1 (Drosophila) | 9446 | -0.031 | -0.3982 | No |
| 52 | LRPPRC | LRPPRC Entrez, Source | leucine-rich PPR-motif containing | 9523 | -0.032 | -0.3983 | No |
| 53 | POLB | POLB Entrez, Source | polymerase (DNA directed), beta | 9596 | -0.033 | -0.3978 | No |
| 54 | RAE1 | RAE1 Entrez, Source | RAE1 RNA export 1 homolog (S. pombe) | 9764 | -0.035 | -0.4041 | No |
| 55 | VAPB | VAPB Entrez, Source | VAMP (vesicle-associated membrane protein)-associated protein B and C | 9787 | -0.035 | -0.3995 | No |
| 56 | ARHGEF2 | ARHGEF2 Entrez, Source | rho/rac guanine nucleotide exchange factor (GEF) 2 | 9794 | -0.035 | -0.3936 | No |
| 57 | BAIAP2 | BAIAP2 Entrez, Source | BAI1-associated protein 2 | 9835 | -0.035 | -0.3902 | No |
| 58 | TNNT1 | TNNT1 Entrez, Source | troponin T type 1 (skeletal, slow) | 10627 | -0.045 | -0.4417 | No |
| 59 | TRIM63 | TRIM63 Entrez, Source | tripartite motif-containing 63 | 10824 | -0.048 | -0.4477 | Yes |
| 60 | CDK5RAP2 | CDK5RAP2 Entrez, Source | CDK5 regulatory subunit associated protein 2 | 10892 | -0.050 | -0.4438 | Yes |
| 61 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 10896 | -0.050 | -0.4350 | Yes |
| 62 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 10920 | -0.050 | -0.4277 | Yes |
| 63 | ANK1 | ANK1 Entrez, Source | ankyrin 1, erythrocytic | 10948 | -0.050 | -0.4206 | Yes |
| 64 | CAPZB | CAPZB Entrez, Source | capping protein (actin filament) muscle Z-line, beta | 11020 | -0.051 | -0.4167 | Yes |
| 65 | DBNL | DBNL Entrez, Source | drebrin-like | 11131 | -0.054 | -0.4153 | Yes |
| 66 | NDE1 | NDE1 Entrez, Source | nudE nuclear distribution gene E homolog 1 (A. nidulans) | 11233 | -0.056 | -0.4129 | Yes |
| 67 | FXYD5 | FXYD5 Entrez, Source | FXYD domain containing ion transport regulator 5 | 11354 | -0.058 | -0.4114 | Yes |
| 68 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 11447 | -0.059 | -0.4076 | Yes |
| 69 | MARCKS | MARCKS Entrez, Source | myristoylated alanine-rich protein kinase C substrate | 11501 | -0.060 | -0.4007 | Yes |
| 70 | SMTN | SMTN Entrez, Source | smoothelin | 11739 | -0.066 | -0.4067 | Yes |
| 71 | KIF5B | KIF5B Entrez, Source | kinesin family member 5B | 11786 | -0.067 | -0.3980 | Yes |
| 72 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 11817 | -0.068 | -0.3880 | Yes |
| 73 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 11925 | -0.070 | -0.3833 | Yes |
| 74 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 11968 | -0.072 | -0.3735 | Yes |
| 75 | ADD1 | ADD1 Entrez, Source | adducin 1 (alpha) | 12055 | -0.074 | -0.3665 | Yes |
| 76 | APC | APC Entrez, Source | adenomatosis polyposis coli | 12071 | -0.075 | -0.3540 | Yes |
| 77 | NCALD | NCALD Entrez, Source | neurocalcin delta | 12273 | -0.082 | -0.3544 | Yes |
| 78 | PXN | PXN Entrez, Source | paxillin | 12322 | -0.084 | -0.3429 | Yes |
| 79 | NRCAM | NRCAM Entrez, Source | neuronal cell adhesion molecule | 12368 | -0.086 | -0.3307 | Yes |
| 80 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 12448 | -0.089 | -0.3206 | Yes |
| 81 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12565 | -0.095 | -0.3122 | Yes |
| 82 | SORBS2 | SORBS2 Entrez, Source | sorbin and SH3 domain containing 2 | 12635 | -0.099 | -0.2996 | Yes |
| 83 | PDLIM5 | PDLIM5 Entrez, Source | PDZ and LIM domain 5 | 12904 | -0.122 | -0.2977 | Yes |
| 84 | ABI2 | ABI2 Entrez, Source | abl interactor 2 | 12931 | -0.125 | -0.2771 | Yes |
| 85 | CLASP1 | CLASP1 Entrez, Source | cytoplasmic linker associated protein 1 | 13168 | -0.170 | -0.2642 | Yes |
| 86 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13174 | -0.172 | -0.2335 | Yes |
| 87 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 13185 | -0.179 | -0.2019 | Yes |
| 88 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13295 | -0.275 | -0.1604 | Yes |
| 89 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -0.905 | -0.0000 | Yes |
