Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_24h_versus_single_gel_24h.class.cls
#double_gel_24h_versus_single_gel_24h_repos
Phenotypeclass.cls#double_gel_24h_versus_single_gel_24h_repos
Upregulated in classsingle_gel_24h
GeneSetCYTOSKELETON
Enrichment Score (ES)-0.33886093
Normalized Enrichment Score (NES)-1.5102684
Nominal p-value0.0020120724
FDR q-value0.2785856
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: CYTOSKELETON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1HSPB1HSPB1
Entrez,  Source
heat shock 27kDa protein 150.3890.0388No
2SPTBN4SPTBN4
Entrez,  Source
spectrin, beta, non-erythrocytic 4710.1920.0532No
3MARK1MARK1
Entrez,  Source
MAP/microtubule affinity-regulating kinase 13230.1320.0474No
4CETN1CETN1
Entrez,  Source
centrin, EF-hand protein, 13640.1290.0574No
5AVILAVIL
Entrez,  Source
advillin3850.1260.0686No
6TNNT2TNNT2
Entrez,  Source
troponin T type 2 (cardiac)4410.1220.0767No
7TNNI3TNNI3
Entrez,  Source
troponin I type 3 (cardiac)6170.1090.0744No
8ABRAABRA
Entrez,  Source
actin-binding Rho activating protein6570.1070.0822No
9MID1MID1
Entrez,  Source
midline 1 (Opitz/BBB syndrome)7310.1030.0870No
10HINT1HINT1
Entrez,  Source
histidine triad nucleotide binding protein 17350.1030.0971No
11KIF5AKIF5A
Entrez,  Source
kinesin family member 5A11450.0860.0747No
12SNIPSNIP
Entrez,  Source
-12370.0820.0760No
13KIF4AKIF4A
Entrez,  Source
kinesin family member 4A15220.0740.0619No
14IVLIVL
Entrez,  Source
involucrin16750.0710.0575No
15ACTL7BACTL7B
Entrez,  Source
actin-like 7B18560.0660.0504No
16AMPHAMPH
Entrez,  Source
amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)18570.0660.0571No
17CACNA1CCACNA1C
Entrez,  Source
calcium channel, voltage-dependent, L type, alpha 1C subunit19390.0640.0574No
18MYH7MYH7
Entrez,  Source
myosin, heavy chain 7, cardiac muscle, beta20240.0620.0572No
19MYL3MYL3
Entrez,  Source
myosin, light chain 3, alkali; ventricular, skeletal, slow20800.0610.0591No
20SYNPOSYNPO
Entrez,  Source
synaptopodin22170.0570.0545No
21AKAP4AKAP4
Entrez,  Source
A kinase (PRKA) anchor protein 422810.0560.0554No
22CCNA1CCNA1
Entrez,  Source
cyclin A124150.0530.0507No
23CEP57CEP57
Entrez,  Source
centrosomal protein 57kDa25030.0520.0492No
24GFAPGFAP
Entrez,  Source
glial fibrillary acidic protein25490.0510.0509No
25NARFNARF
Entrez,  Source
nuclear prelamin A recognition factor28320.0460.0341No
26ARHGDIBARHGDIB
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) beta28790.0450.0351No
27ESPNESPN
Entrez,  Source
espin30000.0430.0303No
28DCXDCX
Entrez,  Source
doublecortex; lissencephaly, X-linked (doublecortin)30920.0420.0276No
29GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)34750.0360.0022No
30HAP1HAP1
Entrez,  Source
huntingtin-associated protein 1 (neuroan 1)35730.034-0.0018No
31ABLIM2ABLIM2
Entrez,  Source
actin binding LIM protein family, member 236390.033-0.0033No
32MAP1BMAP1B
Entrez,  Source
microtubule-associated protein 1B37000.033-0.0046No
33TNNC1TNNC1
Entrez,  Source
troponin C type 1 (slow)38350.031-0.0117No
34BMFBMF
Entrez,  Source
Bcl2 modifying factor40200.028-0.0229No
35SLC4A1SLC4A1
Entrez,  Source
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)40490.028-0.0222No
36DRD2DRD2
Entrez,  Source
dopamine receptor D240820.027-0.0219No
37CORO1ACORO1A
Entrez,  Source
coronin, actin binding protein, 1A41240.027-0.0223No
38KATNA1KATNA1
Entrez,  Source
katanin p60 (ATPase-containing) subunit A 143940.023-0.0404No
39WASF2WASF2
Entrez,  Source
WAS protein family, member 244330.023-0.0410No
40MYH6MYH6
Entrez,  Source
myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)46700.020-0.0569No
41TRPC4TRPC4
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 447220.019-0.0588No
42DNALI1DNALI1
Entrez,  Source
dynein, axonemal, light intermediate chain 147530.019-0.0592No
43NF2NF2
Entrez,  Source
neurofibromin 2 (bilateral acoustic neuroma)50260.016-0.0783No
44BIRC5BIRC5
Entrez,  Source
baculoviral IAP repeat-containing 5 (survivin)50830.015-0.0810No
45BRCA2BRCA2
Entrez,  Source
breast cancer 2, early onset52130.014-0.0895No
46NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)52220.013-0.0887No
47KIFC3KIFC3
Entrez,  Source
kinesin family member C353450.012-0.0968No
48MAPTMAPT
Entrez,  Source
microtubule-associated protein tau54610.011-0.1044No
49TPT1TPT1
Entrez,  Source
tumor protein, translationally-controlled 154800.010-0.1048No
50MEFVMEFV
Entrez,  Source
Mediterranean fever55820.009-0.1115No
51CABP1CABP1
Entrez,  Source
calcium binding protein 1 (calbrain)56530.008-0.1160No
52UTRNUTRN
Entrez,  Source
utrophin (homologous to dystrophin)60050.005-0.1422No
53ZW10ZW10
Entrez,  Source
ZW10, kinetochore associated, homolog (Drosophila)60130.004-0.1422No
54ABCA2ABCA2
Entrez,  Source
ATP-binding cassette, sub-family A (ABC1), member 261130.004-0.1494No
55PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa63050.001-0.1638No
56TUBB2CTUBB2C
Entrez,  Source
tubulin, beta 2C64010.000-0.1710No
57DYNC1I1DYNC1I1
Entrez,  Source
dynein, cytoplasmic 1, intermediate chain 16548-0.001-0.1819No
58MAP1AMAP1A
Entrez,  Source
microtubule-associated protein 1A6569-0.002-0.1833No
59CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)6620-0.002-0.1869No
60ARHGDIAARHGDIA
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) alpha6645-0.002-0.1884No
61TUBGCP3TUBGCP3
Entrez,  Source
tubulin, gamma complex associated protein 36657-0.003-0.1890No
62CCT3CCT3
Entrez,  Source
chaperonin containing TCP1, subunit 3 (gamma)6694-0.003-0.1915No
63PLK1PLK1
Entrez,  Source
polo-like kinase 1 (Drosophila)6701-0.003-0.1916No
64SEPT9SEPT9
Entrez,  Source
septin 96891-0.005-0.2055No
65GAS8GAS8
Entrez,  Source
growth arrest-specific 86906-0.005-0.2061No
66DDX20DDX20
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 206922-0.005-0.2068No
67FSCN3FSCN3
Entrez,  Source
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)6957-0.005-0.2088No
68CDC20CDC20
Entrez,  Source
CDC20 cell division cycle 20 homolog (S. cerevisiae)6975-0.005-0.2096No
69ATG4BATG4B
Entrez,  Source
ATG4 autophagy related 4 homolog B (S. cerevisiae)7075-0.006-0.2165No
70KALRNKALRN
Entrez,  Source
kalirin, RhoGEF kinase7103-0.007-0.2179No
71LSP1LSP1
Entrez,  Source
lymphocyte-specific protein 17298-0.009-0.2317No
72HDAC6HDAC6
Entrez,  Source
histone deacetylase 67465-0.010-0.2433No
73ANXA1ANXA1
Entrez,  Source
annexin A17517-0.011-0.2461No
74SEPT7SEPT7
Entrez,  Source
septin 77594-0.011-0.2507No
75ALS2ALS2
Entrez,  Source
amyotrophic lateral sclerosis 2 (juvenile)7724-0.013-0.2592No
76BIN1BIN1
Entrez,  Source
bridging integrator 17729-0.013-0.2583No
77NEDD9NEDD9
Entrez,  Source
neural precursor cell expressed, developmentally down-regulated 97794-0.013-0.2618No
78NUMA1NUMA1
Entrez,  Source
nuclear mitotic apparatus protein 17818-0.014-0.2621No
79FLNBFLNB
Entrez,  Source
filamin B, beta (actin binding protein 278)7935-0.015-0.2694No
80GABARAPL2GABARAPL2
Entrez,  Source
GABA(A) receptor-associated protein-like 28016-0.016-0.2739No
81ACTBACTB
Entrez,  Source
actin, beta8105-0.017-0.2789No
82CAPZA2CAPZA2
Entrez,  Source
capping protein (actin filament) muscle Z-line, alpha 28236-0.018-0.2870No
83TBCETBCE
Entrez,  Source
tubulin-specific chaperone e8239-0.018-0.2853No
84CAPGCAPG
Entrez,  Source
capping protein (actin filament), gelsolin-like8248-0.018-0.2841No
85LYSTLYST
Entrez,  Source
lysosomal trafficking regulator8300-0.019-0.2861No
86SIRT2SIRT2
Entrez,  Source
sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)8333-0.019-0.2866No
87CLIC5CLIC5
Entrez,  Source
chloride intracellular channel 58412-0.020-0.2905No
88CTNNB1CTNNB1
Entrez,  Source
catenin (cadherin-associated protein), beta 1, 88kDa8471-0.020-0.2929No
89MAPRE1MAPRE1
Entrez,  Source
microtubule-associated protein, RP/EB family, member 18516-0.021-0.2941No
90STAU1STAU1
Entrez,  Source
staufen, RNA binding protein, homolog 1 (Drosophila)8520-0.021-0.2922No
91KIF3CKIF3C
Entrez,  Source
kinesin family member 3C8551-0.021-0.2924No
92TSC1TSC1
Entrez,  Source
tuberous sclerosis 18579-0.022-0.2922No
93ARPC1AARPC1A
Entrez,  Source
actin related protein 2/3 complex, subunit 1A, 41kDa8606-0.022-0.2920No
94DYNLL2DYNLL2
Entrez,  Source
dynein, light chain, LC8-type 28613-0.022-0.2903No
95CDC16CDC16
Entrez,  Source
CDC16 cell division cycle 16 homolog (S. cerevisiae)8614-0.022-0.2880No
96HIP1HIP1
Entrez,  Source
huntingtin interacting protein 18701-0.023-0.2923No
97ACTR2ACTR2
Entrez,  Source
ARP2 actin-related protein 2 homolog (yeast)8777-0.024-0.2956No
98CDC42BPBCDC42BPB
Entrez,  Source
CDC42 binding protein kinase beta (DMPK-like)8784-0.024-0.2937No
99MYO9BMYO9B
Entrez,  Source
myosin IXB8864-0.025-0.2972No
100CCNB2CCNB2
Entrez,  Source
cyclin B28905-0.025-0.2977No
101DCTN4DCTN4
Entrez,  Source
dynactin 4 (p62)8948-0.025-0.2983No
102ACTR1BACTR1B
Entrez,  Source
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)9228-0.028-0.3167No
103MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 119302-0.029-0.3193No
104TOP2ATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa9337-0.029-0.3189No
105LRPPRCLRPPRC
Entrez,  Source
leucine-rich PPR-motif containing9523-0.032-0.3298No
106POLBPOLB
Entrez,  Source
polymerase (DNA directed), beta9596-0.033-0.3320No
107TSGA14TSGA14
Entrez,  Source
testis specific, 149628-0.033-0.3310No
108AURKAAURKA
Entrez,  Source
aurora kinase A9667-0.034-0.3305No
109CTTNCTTN
Entrez,  Source
cortactin9710-0.034-0.3302No
110RAE1RAE1
Entrez,  Source
RAE1 RNA export 1 homolog (S. pombe)9764-0.035-0.3308No
111ARHGEF2ARHGEF2
Entrez,  Source
rho/rac guanine nucleotide exchange factor (GEF) 29794-0.035-0.3294No
112ACTR3ACTR3
Entrez,  Source
ARP3 actin-related protein 3 homolog (yeast)9840-0.036-0.3293No
113MYL2MYL2
Entrez,  Source
myosin, light chain 2, regulatory, cardiac, slow9897-0.036-0.3299No
114APPBP2APPBP2
Entrez,  Source
amyloid beta precursor protein (cytoplasmic tail) binding protein 29965-0.037-0.3313No
115CETN3CETN3
Entrez,  Source
centrin, EF-hand protein, 3 (CDC31 homolog, yeast)10040-0.038-0.3331No
116NUDT21NUDT21
Entrez,  Source
nudix (nucleoside diphosphate linked moiety X)-type motif 2110044-0.038-0.3296No
117STOML2STOML2
Entrez,  Source
stomatin (EPB72)-like 210058-0.038-0.3267No
118KIF2CKIF2C
Entrez,  Source
kinesin family member 2C10085-0.038-0.3249No
119GYS2GYS2
Entrez,  Source
glycogen synthase 2 (liver)10212-0.040-0.3304No
120DYNLL1DYNLL1
Entrez,  Source
dynein, light chain, LC8-type 110216-0.040-0.3267No
121LMNB1LMNB1
Entrez,  Source
lamin B110273-0.040-0.3269No
122CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase10368-0.041-0.3298No
123SMC3SMC3
Entrez,  Source
structural maintenance of chromosomes 310429-0.042-0.3301No
124NEFLNEFL
Entrez,  Source
neurofilament, light polypeptide 68kDa10506-0.044-0.3315No
125DCTN2DCTN2
Entrez,  Source
dynactin 2 (p50)10509-0.044-0.3273No
126LASP1LASP1
Entrez,  Source
LIM and SH3 protein 110631-0.045-0.3319No
127TPM3TPM3
Entrez,  Source
tropomyosin 310717-0.047-0.3337No
128CKAP5CKAP5
Entrez,  Source
cytoskeleton associated protein 510786-0.048-0.3340Yes
129ARPC1BARPC1B
Entrez,  Source
actin related protein 2/3 complex, subunit 1B, 41kDa10805-0.048-0.3306Yes
130CDK5RAP2CDK5RAP2
Entrez,  Source
CDK5 regulatory subunit associated protein 210892-0.050-0.3321Yes
131DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)10896-0.050-0.3274Yes
132MYH9MYH9
Entrez,  Source
myosin, heavy chain 9, non-muscle10920-0.050-0.3241Yes
133CAPZBCAPZB
Entrez,  Source
capping protein (actin filament) muscle Z-line, beta11020-0.051-0.3264Yes
134DCTN1DCTN1
Entrez,  Source
dynactin 1 (p150, glued homolog, Drosophila)11141-0.054-0.3301Yes
135WASF1WASF1
Entrez,  Source
WAS protein family, member 111176-0.054-0.3272Yes
136WASLWASL
Entrez,  Source
Wiskott-Aldrich syndrome-like11185-0.055-0.3224Yes
137NDE1NDE1
Entrez,  Source
nudE nuclear distribution gene E homolog 1 (A. nidulans)11233-0.056-0.3203Yes
138KATNB1KATNB1
Entrez,  Source
katanin p80 (WD repeat containing) subunit B 111300-0.057-0.3196Yes
139ARPC5ARPC5
Entrez,  Source
actin related protein 2/3 complex, subunit 5, 16kDa11304-0.057-0.3141Yes
140ACTN3ACTN3
Entrez,  Source
actinin, alpha 311323-0.057-0.3097Yes
141TUBBTUBB
Entrez,  Source
tubulin, beta11384-0.058-0.3084Yes
142KIF1BKIF1B
Entrez,  Source
kinesin family member 1B11447-0.059-0.3071Yes
143MARCKSMARCKS
Entrez,  Source
myristoylated alanine-rich protein kinase C substrate11501-0.060-0.3050Yes
144DSPDSP
Entrez,  Source
desmoplakin11506-0.060-0.2992Yes
145STOMSTOM
Entrez,  Source
stomatin11510-0.061-0.2934Yes
146MYOM1MYOM1
Entrez,  Source
myomesin 1 (skelemin) 185kDa11511-0.061-0.2873Yes
147CDC27CDC27
Entrez,  Source
cell division cycle 2711606-0.063-0.2881Yes
148PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 211607-0.063-0.2818Yes
149SMTNSMTN
Entrez,  Source
smoothelin11739-0.066-0.2851Yes
150PTPN21PTPN21
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 2111756-0.066-0.2797Yes
151DAG1DAG1
Entrez,  Source
dystroglycan 1 (dystrophin-associated glycoprotein 1)11785-0.067-0.2751Yes
152KIF5BKIF5B
Entrez,  Source
kinesin family member 5B11786-0.067-0.2683Yes
153UXTUXT
Entrez,  Source
ubiquitously-expressed transcript11925-0.070-0.2717Yes
154ACTC1ACTC1
Entrez,  Source
actin, alpha, cardiac muscle 111932-0.071-0.2650Yes
155CLASP2CLASP2
Entrez,  Source
cytoplasmic linker associated protein 211968-0.072-0.2605Yes
156PCM1PCM1
Entrez,  Source
pericentriolar material 112064-0.075-0.2601Yes
157APCAPC
Entrez,  Source
adenomatosis polyposis coli12071-0.075-0.2530Yes
158VIMVIM
Entrez,  Source
vimentin12125-0.077-0.2493Yes
159PXNPXN
Entrez,  Source
paxillin12322-0.084-0.2558Yes
160SLC9A3R1SLC9A3R1
Entrez,  Source
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 112376-0.086-0.2512Yes
161CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 412392-0.087-0.2436Yes
162CASKCASK
Entrez,  Source
calcium/calmodulin-dependent serine protein kinase (MAGUK family)12444-0.088-0.2385Yes
163TUBG1TUBG1
Entrez,  Source
tubulin, gamma 112486-0.090-0.2326Yes
164CALD1CALD1
Entrez,  Source
caldesmon 112565-0.095-0.2289Yes
165SORBS2SORBS2
Entrez,  Source
sorbin and SH3 domain containing 212635-0.099-0.2243Yes
166DYNC1LI2DYNC1LI2
Entrez,  Source
dynein, cytoplasmic 1, light intermediate chain 212827-0.113-0.2274Yes
167MYO1CMYO1C
Entrez,  Source
myosin IC12875-0.118-0.2190Yes
168PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 512904-0.122-0.2089Yes
169AKAP9AKAP9
Entrez,  Source
A kinase (PRKA) anchor protein (yotiao) 912906-0.122-0.1967Yes
170TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)12937-0.125-0.1864Yes
171TPM4TPM4
Entrez,  Source
tropomyosin 412972-0.128-0.1760Yes
172BASP1BASP1
Entrez,  Source
brain abundant, membrane attached signal protein 113143-0.159-0.1729Yes
173CLASP1CLASP1
Entrez,  Source
cytoplasmic linker associated protein 113168-0.170-0.1576Yes
174MYH10MYH10
Entrez,  Source
myosin, heavy chain 10, non-muscle13185-0.179-0.1409Yes
175EML2EML2
Entrez,  Source
echinoderm microtubule associated protein like 213203-0.193-0.1227Yes
176TGM1TGM1
Entrez,  Source
transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)13217-0.203-0.1033Yes
177MSNMSN
Entrez,  Source
moesin13233-0.213-0.0829Yes
178ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle13342-0.905-0.0000Yes
Table: GSEA details [plain text format]



Fig 2: CYTOSKELETON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CYTOSKELETON: Random ES distribution   
Gene set null distribution of ES for CYTOSKELETON