Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | DEATHPATHWAY |
| Enrichment Score (ES) | -0.6240777 |
| Normalized Enrichment Score (NES) | -1.871893 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.099659376 |
| FWER p-Value | 0.845 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BIRC2 | BIRC2 Entrez, Source | baculoviral IAP repeat-containing 2 | 5286 | 0.013 | -0.3856 | No |
| 2 | LMNA | LMNA Entrez, Source | lamin A/C | 6554 | -0.001 | -0.4794 | No |
| 3 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 6812 | -0.004 | -0.4954 | No |
| 4 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 7260 | -0.008 | -0.5217 | No |
| 5 | DFFB | DFFB Entrez, Source | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 7293 | -0.009 | -0.5165 | No |
| 6 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 7301 | -0.009 | -0.5094 | No |
| 7 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 7500 | -0.010 | -0.5150 | No |
| 8 | CASP7 | CASP7 Entrez, Source | caspase 7, apoptosis-related cysteine peptidase | 8153 | -0.017 | -0.5489 | No |
| 9 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 8779 | -0.024 | -0.5749 | No |
| 10 | BIRC4 | BIRC4 Entrez, Source | baculoviral IAP repeat-containing 4 | 8879 | -0.025 | -0.5605 | No |
| 11 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 9040 | -0.026 | -0.5491 | No |
| 12 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 9174 | -0.028 | -0.5345 | No |
| 13 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 10368 | -0.041 | -0.5875 | Yes |
| 14 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 10649 | -0.045 | -0.5683 | Yes |
| 15 | DFFA | DFFA Entrez, Source | DNA fragmentation factor, 45kDa, alpha polypeptide | 11119 | -0.053 | -0.5565 | Yes |
| 16 | TNFSF12 | TNFSF12 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 12 | 11721 | -0.065 | -0.5440 | Yes |
| 17 | CFLAR | CFLAR Entrez, Source | CASP8 and FADD-like apoptosis regulator | 11917 | -0.070 | -0.4967 | Yes |
| 18 | BID | BID Entrez, Source | BH3 interacting domain death agonist | 12134 | -0.077 | -0.4448 | Yes |
| 19 | FADD | FADD Entrez, Source | Fas (TNFRSF6)-associated via death domain | 12156 | -0.078 | -0.3776 | Yes |
| 20 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 12964 | -0.127 | -0.3257 | Yes |
| 21 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 13071 | -0.143 | -0.2070 | Yes |
| 22 | APAF1 | APAF1 Entrez, Source | apoptotic peptidase activating factor | 13280 | -0.257 | 0.0047 | Yes |
