Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | EGF_HDMEC_UP |
| Enrichment Score (ES) | -0.46754327 |
| Normalized Enrichment Score (NES) | -1.5322753 |
| Nominal p-value | 0.03420523 |
| FDR q-value | 0.2745035 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 5 | 0.389 | 0.1570 | No |
| 2 | DDIT3 | DDIT3 Entrez, Source | DNA-damage-inducible transcript 3 | 356 | 0.129 | 0.1829 | No |
| 3 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 1596 | 0.073 | 0.1192 | No |
| 4 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 1933 | 0.064 | 0.1198 | No |
| 5 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 2505 | 0.051 | 0.0978 | No |
| 6 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 3714 | 0.032 | 0.0201 | No |
| 7 | TIE1 | TIE1 Entrez, Source | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 4980 | 0.016 | -0.0684 | No |
| 8 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 5034 | 0.016 | -0.0660 | No |
| 9 | DAD1 | DAD1 Entrez, Source | defender against cell death 1 | 5035 | 0.016 | -0.0597 | No |
| 10 | RAD23B | RAD23B Entrez, Source | RAD23 homolog B (S. cerevisiae) | 5366 | 0.012 | -0.0798 | No |
| 11 | HSP90AA1 | HSP90AA1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 6167 | 0.003 | -0.1387 | No |
| 12 | GPI | GPI Entrez, Source | glucose phosphate isomerase | 6497 | -0.001 | -0.1632 | No |
| 13 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 6805 | -0.004 | -0.1847 | No |
| 14 | GSTM1 | GSTM1 Entrez, Source | glutathione S-transferase M1 | 6956 | -0.005 | -0.1939 | No |
| 15 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 7301 | -0.009 | -0.2162 | No |
| 16 | TCEB1 | TCEB1 Entrez, Source | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 7679 | -0.012 | -0.2396 | No |
| 17 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 8143 | -0.017 | -0.2675 | No |
| 18 | RPL6 | RPL6 Entrez, Source | ribosomal protein L6 | 8558 | -0.021 | -0.2900 | No |
| 19 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 9174 | -0.028 | -0.3249 | No |
| 20 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 9198 | -0.028 | -0.3153 | No |
| 21 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 9302 | -0.029 | -0.3113 | No |
| 22 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 9784 | -0.035 | -0.3333 | No |
| 23 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 9864 | -0.036 | -0.3248 | No |
| 24 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 10063 | -0.038 | -0.3243 | No |
| 25 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 10216 | -0.040 | -0.3197 | No |
| 26 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11016 | -0.051 | -0.3590 | No |
| 27 | GNAS | GNAS Entrez, Source | GNAS complex locus | 12462 | -0.089 | -0.4313 | Yes |
| 28 | TMSB10 | TMSB10 Entrez, Source | thymosin, beta 10 | 12891 | -0.120 | -0.4149 | Yes |
| 29 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 13105 | -0.150 | -0.3701 | Yes |
| 30 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 13167 | -0.169 | -0.3063 | Yes |
| 31 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13262 | -0.231 | -0.2198 | Yes |
| 32 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13284 | -0.263 | -0.1151 | Yes |
| 33 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13302 | -0.295 | 0.0030 | Yes |
