Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_24h_versus_single_gel_24h.class.cls
#double_gel_24h_versus_single_gel_24h_repos
Phenotypeclass.cls#double_gel_24h_versus_single_gel_24h_repos
Upregulated in classdouble_gel_24h
GeneSetEXTRACELLULAR_REGION
Enrichment Score (ES)0.33257246
Normalized Enrichment Score (NES)1.5838908
Nominal p-value0.0
FDR q-value0.22453877
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: EXTRACELLULAR_REGION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1LYZLYZ
Entrez,  Source
lysozyme (renal amyloidosis)340.2300.0112Yes
2FGF21FGF21
Entrez,  Source
fibroblast growth factor 21530.2100.0223Yes
3TMPRSS11DTMPRSS11D
Entrez,  Source
transmembrane protease, serine 11D970.1800.0298Yes
4PLA2G2DPLA2G2D
Entrez,  Source
phospholipase A2, group IID1080.1750.0395Yes
5ACE2ACE2
Entrez,  Source
angiotensin I converting enzyme (peptidyl-dipeptidase A) 21590.1570.0450Yes
6FGF16FGF16
Entrez,  Source
fibroblast growth factor 162070.1480.0503Yes
7PLGPLG
Entrez,  Source
plasminogen2290.1440.0573Yes
8MMP10MMP10
Entrez,  Source
matrix metallopeptidase 10 (stromelysin 2)2490.1410.0644Yes
9FBN2FBN2
Entrez,  Source
fibrillin 2 (congenital contractural arachnodactyly)3680.1280.0630Yes
10NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)3770.1280.0700Yes
11RBP4RBP4
Entrez,  Source
retinol binding protein 4, plasma4870.1190.0688Yes
12LTBP2LTBP2
Entrez,  Source
latent transforming growth factor beta binding protein 25080.1170.0742Yes
13INHBCINHBC
Entrez,  Source
inhibin, beta C5180.1160.0805Yes
14MMP2MMP2
Entrez,  Source
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)5270.1150.0867Yes
15APOA1APOA1
Entrez,  Source
apolipoprotein A-I5520.1130.0917Yes
16SLIT1SLIT1
Entrez,  Source
slit homolog 1 (Drosophila)5710.1120.0970Yes
17IGFBP1IGFBP1
Entrez,  Source
insulin-like growth factor binding protein 15780.1120.1032Yes
18GRPGRP
Entrez,  Source
gastrin-releasing peptide5950.1110.1086Yes
19PRSS8PRSS8
Entrez,  Source
protease, serine, 8 (prostasin)6760.1050.1088Yes
20IL6RIL6R
Entrez,  Source
interleukin 6 receptor6950.1040.1137Yes
21EPOEPO
Entrez,  Source
erythropoietin7320.1030.1171Yes
22SEMA3ASEMA3A
Entrez,  Source
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A7550.1020.1215Yes
23MEP1BMEP1B
Entrez,  Source
meprin A, beta7580.1010.1274Yes
24TGFB1TGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)7630.1010.1331Yes
25FGBFGB
Entrez,  Source
fibrinogen beta chain8000.1000.1363Yes
26IL4IL4
Entrez,  Source
interleukin 48240.0980.1405Yes
27IL3IL3
Entrez,  Source
interleukin 3 (colony-stimulating factor, multiple)8660.0970.1431Yes
28SPNSPN
Entrez,  Source
sialophorin (leukosialin, CD43)8840.0960.1476Yes
29CX3CL1CX3CL1
Entrez,  Source
chemokine (C-X3-C motif) ligand 18940.0960.1526Yes
30COL10A1COL10A1
Entrez,  Source
collagen, type X, alpha 1(Schmid metaphyseal chondrodysplasia)9080.0950.1573Yes
31MEP1AMEP1A
Entrez,  Source
meprin A, alpha (PABA peptide hydrolase)9270.0940.1616Yes
32SPINT1SPINT1
Entrez,  Source
serine peptidase inhibitor, Kunitz type 19530.0930.1653Yes
33GPC1GPC1
Entrez,  Source
glypican 19760.0920.1691Yes
34FSTL1FSTL1
Entrez,  Source
follistatin-like 110100.0910.1720Yes
35ADFPADFP
Entrez,  Source
adipose differentiation-related protein10460.0900.1747Yes
36CFHR1CFHR1
Entrez,  Source
complement factor H-related 110680.0880.1784Yes
37IL9RIL9R
Entrez,  Source
interleukin 9 receptor10940.0870.1817Yes
38PRELPPRELP
Entrez,  Source
proline/arginine-rich end leucine-rich repeat protein10960.0870.1868Yes
39IL12BIL12B
Entrez,  Source
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)10970.0870.1921Yes
40LPLLPL
Entrez,  Source
lipoprotein lipase11160.0870.1959Yes
41COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 211220.0860.2007Yes
42TAC1TAC1
Entrez,  Source
tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)11710.0850.2021Yes
43INHBAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)11740.0850.2070Yes
44FBLN5FBLN5
Entrez,  Source
fibulin 511960.0840.2104Yes
45AREGAREG
Entrez,  Source
amphiregulin (schwannoma-derived growth factor)12150.0830.2140Yes
46THBS4THBS4
Entrez,  Source
thrombospondin 412220.0830.2185Yes
47FGF3FGF3
Entrez,  Source
fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)12280.0830.2230Yes
48AMHAMH
Entrez,  Source
anti-Mullerian hormone12440.0820.2268Yes
49CARTPTCARTPT
Entrez,  Source
CART prepropeptide12780.0810.2291Yes
50DMP1DMP1
Entrez,  Source
dentin matrix acidic phosphoprotein12960.0800.2326Yes
51FGAFGA
Entrez,  Source
fibrinogen alpha chain13020.0800.2370Yes
52SGCGSGCG
Entrez,  Source
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)13100.0800.2413Yes
53MGPMGP
Entrez,  Source
matrix Gla protein13410.0790.2437Yes
54MYOCMYOC
Entrez,  Source
myocilin, trabecular meshwork inducible glucocorticoid response14180.0770.2425Yes
55PCSK5PCSK5
Entrez,  Source
proprotein convertase subtilisin/kexin type 514800.0750.2424Yes
56WNT2BWNT2B
Entrez,  Source
wingless-type MMTV integration site family, member 2B15260.0740.2433Yes
57FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)15590.0730.2453Yes
58COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 415610.0730.2496Yes
59FGGFGG
Entrez,  Source
fibrinogen gamma chain16190.0720.2495Yes
60CTRLCTRL
Entrez,  Source
chymotrypsin-like16290.0720.2531Yes
61CHI3L1CHI3L1
Entrez,  Source
chitinase 3-like 1 (cartilage glycoprotein-39)16350.0720.2570Yes
62HAPLN1HAPLN1
Entrez,  Source
hyaluronan and proteoglycan link protein 116820.0700.2577Yes
63CCL22CCL22
Entrez,  Source
chemokine (C-C motif) ligand 2217020.0700.2604Yes
64LIPELIPE
Entrez,  Source
lipase, hormone-sensitive17390.0690.2618Yes
65NUCB2NUCB2
Entrez,  Source
nucleobindin 218110.0670.2604Yes
66COL5A1COL5A1
Entrez,  Source
collagen, type V, alpha 118260.0670.2633Yes
67COL15A1COL15A1
Entrez,  Source
collagen, type XV, alpha 118380.0670.2664Yes
68FRZBFRZB
Entrez,  Source
frizzled-related protein18390.0670.2704Yes
69SCG2SCG2
Entrez,  Source
secretogranin II (chromogranin C)18430.0660.2742Yes
70KLK8KLK8
Entrez,  Source
kallikrein 8 (neuropsin/ovasin)18540.0660.2773Yes
71MFNGMFNG
Entrez,  Source
manic fringe homolog (Drosophila)18820.0650.2792Yes
72PTGDSPTGDS
Entrez,  Source
prostaglandin D2 synthase 21kDa (brain)19060.0650.2813Yes
73SCRG1SCRG1
Entrez,  Source
-19160.0640.2845Yes
74MSMBMSMB
Entrez,  Source
microseminoprotein, beta-19250.0640.2877Yes
75LBPLBP
Entrez,  Source
lipopolysaccharide binding protein19400.0640.2904Yes
76KLK10KLK10
Entrez,  Source
kallikrein 1019720.0630.2918Yes
77FGF6FGF6
Entrez,  Source
fibroblast growth factor 619810.0630.2950Yes
78SERPINA5SERPINA5
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 520420.0610.2941Yes
79USH2AUSH2A
Entrez,  Source
Usher syndrome 2A (autosomal recessive, mild)20640.0610.2961Yes
80LCATLCAT
Entrez,  Source
lecithin-cholesterol acyltransferase20890.0600.2979Yes
81LEPLEP
Entrez,  Source
leptin (obesity homolog, mouse)21770.0580.2947Yes
82ADMADM
Entrez,  Source
adrenomedullin21890.0580.2973Yes
83PCSK9PCSK9
Entrez,  Source
proprotein convertase subtilisin/kexin type 921940.0580.3005Yes
84CSF3CSF3
Entrez,  Source
colony stimulating factor 3 (granulocyte)22130.0570.3025Yes
85SECTM1SECTM1
Entrez,  Source
secreted and transmembrane 122390.0570.3040Yes
86FGF2FGF2
Entrez,  Source
fibroblast growth factor 2 (basic)22530.0560.3064Yes
87TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 222820.0560.3075Yes
88MATN1MATN1
Entrez,  Source
matrilin 1, cartilage matrix protein23030.0550.3093Yes
89DMBT1DMBT1
Entrez,  Source
deleted in malignant brain tumors 123680.0540.3077Yes
90GHRLGHRL
Entrez,  Source
ghrelin/obestatin preprohormone24170.0530.3072Yes
91AFMAFM
Entrez,  Source
afamin24310.0530.3094Yes
92GREM1GREM1
Entrez,  Source
gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)24340.0530.3124Yes
93ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)24560.0530.3139Yes
94CCL28CCL28
Entrez,  Source
chemokine (C-C motif) ligand 2824940.0520.3142Yes
95IMPG2IMPG2
Entrez,  Source
interphotoreceptor matrix proteoglycan 225000.0520.3169Yes
96FGF10FGF10
Entrez,  Source
fibroblast growth factor 1025820.0500.3137Yes
97PCSK2PCSK2
Entrez,  Source
proprotein convertase subtilisin/kexin type 225880.0500.3163Yes
98IL5RAIL5RA
Entrez,  Source
interleukin 5 receptor, alpha26040.0500.3181Yes
99SFTPDSFTPD
Entrez,  Source
surfactant, pulmonary-associated protein D26450.0490.3180Yes
100AMY2AAMY2A
Entrez,  Source
amylase, alpha 2A; pancreatic26540.0490.3203Yes
101COLQCOLQ
Entrez,  Source
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase26570.0490.3231Yes
102CALCACALCA
Entrez,  Source
calcitonin/calcitonin-related polypeptide, alpha26810.0480.3242Yes
103COL16A1COL16A1
Entrez,  Source
collagen, type XVI, alpha 127230.0480.3239Yes
104FMODFMOD
Entrez,  Source
fibromodulin27610.0470.3239Yes
105DSPPDSPP
Entrez,  Source
dentin sialophosphoprotein28040.0460.3234Yes
106MMP8MMP8
Entrez,  Source
matrix metallopeptidase 8 (neutrophil collagenase)28630.0450.3217Yes
107DKK3DKK3
Entrez,  Source
dickkopf homolog 3 (Xenopus laevis)28700.0450.3239Yes
108CPA1CPA1
Entrez,  Source
carboxypeptidase A1 (pancreatic)29390.0440.3213Yes
109UTS2UTS2
Entrez,  Source
urotensin 229510.0440.3231Yes
110IL13RA2IL13RA2
Entrez,  Source
interleukin 13 receptor, alpha 229620.0440.3250Yes
111SCUBE1SCUBE1
Entrez,  Source
signal peptide, CUB domain, EGF-like 129940.0430.3252Yes
112IGFALSIGFALS
Entrez,  Source
insulin-like growth factor binding protein, acid labile subunit29970.0430.3276Yes
113FGF20FGF20
Entrez,  Source
fibroblast growth factor 2030050.0430.3296Yes
114SLIT2SLIT2
Entrez,  Source
slit homolog 2 (Drosophila)30060.0430.3322Yes
115IL6IL6
Entrez,  Source
interleukin 6 (interferon, beta 2)30350.0430.3326Yes
116F13A1F13A1
Entrez,  Source
coagulation factor XIII, A1 polypeptide30940.0420.3306No
117FGFBP1FGFBP1
Entrez,  Source
fibroblast growth factor binding protein 131310.0410.3303No
118COL5A2COL5A2
Entrez,  Source
collagen, type V, alpha 231690.0410.3299No
119WNT5AWNT5A
Entrez,  Source
wingless-type MMTV integration site family, member 5A31950.0400.3304No
120ANGPTL4ANGPTL4
Entrez,  Source
angiopoietin-like 432260.0400.3305No
121PTNPTN
Entrez,  Source
pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)33180.0380.3258No
122EREGEREG
Entrez,  Source
epiregulin33910.0370.3225No
123IL1RNIL1RN
Entrez,  Source
interleukin 1 receptor antagonist34000.0370.3241No
124FIGFFIGF
Entrez,  Source
c-fos induced growth factor (vascular endothelial growth factor D)34230.0360.3245No
125GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)34750.0360.3228No
126F2F2
Entrez,  Source
coagulation factor II (thrombin)34960.0350.3234No
127COPACOPA
Entrez,  Source
coatomer protein complex, subunit alpha35100.0350.3245No
128SFRP1SFRP1
Entrez,  Source
secreted frizzled-related protein 135330.0350.3249No
129PCSK1NPCSK1N
Entrez,  Source
proprotein convertase subtilisin/kexin type 1 inhibitor35520.0350.3255No
130FSTL3FSTL3
Entrez,  Source
follistatin-like 3 (secreted glycoprotein)35630.0340.3268No
131KLK6KLK6
Entrez,  Source
kallikrein 6 (neurosin, zyme)36630.0330.3212No
132DLK1DLK1
Entrez,  Source
delta-like 1 homolog (Drosophila)36950.0330.3208No
133FGL1FGL1
Entrez,  Source
fibrinogen-like 137130.0320.3214No
134MUC5ACMUC5AC
Entrez,  Source
mucin 5AC, oligomeric mucus/gel-forming38080.0310.3161No
135CFHCFH
Entrez,  Source
complement factor H38410.0300.3155No
136CHADCHAD
Entrez,  Source
chondroadherin38550.0300.3163No
137GPHA2GPHA2
Entrez,  Source
glycoprotein hormone alpha 238850.0300.3158No
138CPCP
Entrez,  Source
ceruloplasmin (ferroxidase)39120.0300.3156No
139KLKL
Entrez,  Source
klotho39880.0290.3116No
140LGALS7LGALS7
Entrez,  Source
lectin, galactoside-binding, soluble, 7 (galectin 7)39920.0290.3131No
141FBN1FBN1
Entrez,  Source
fibrillin 140080.0280.3136No
142FBLN2FBLN2
Entrez,  Source
fibulin 240770.0270.3100No
143EFNA5EFNA5
Entrez,  Source
ephrin-A541280.0270.3078No
144SFRP4SFRP4
Entrez,  Source
secreted frizzled-related protein 441440.0260.3082No
145INHAINHA
Entrez,  Source
inhibin, alpha42340.0250.3029No
146FGL2FGL2
Entrez,  Source
fibrinogen-like 242530.0250.3031No
147PNLIPRP2PNLIPRP2
Entrez,  Source
pancreatic lipase-related protein 242660.0250.3036No
148MMP3MMP3
Entrez,  Source
matrix metallopeptidase 3 (stromelysin 1, progelatinase)44120.0230.2939No
149VTNVTN
Entrez,  Source
vitronectin44130.0230.2953No
150A1BGA1BG
Entrez,  Source
alpha-1-B glycoprotein45810.0210.2838No
151LOXL1LOXL1
Entrez,  Source
lysyl oxidase-like 146510.0200.2797No
152CLEC11ACLEC11A
Entrez,  Source
C-type lectin domain family 11, member A47050.0200.2768No
153PRG2PRG2
Entrez,  Source
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)47180.0190.2770No
154IL18IL18
Entrez,  Source
interleukin 18 (interferon-gamma-inducing factor)47310.0190.2773No
155PLA2G2APLA2G2A
Entrez,  Source
phospholipase A2, group IIA (platelets, synovial fluid)47970.0190.2734No
156GDNFGDNF
Entrez,  Source
glial cell derived neurotrophic factor48280.0180.2722No
157GPX3GPX3
Entrez,  Source
glutathione peroxidase 3 (plasma)48420.0180.2723No
158C1QBC1QB
Entrez,  Source
complement component 1, q subcomponent, B chain48910.0180.2696No
159IL2IL2
Entrez,  Source
interleukin 248930.0170.2706No
160CPB2CPB2
Entrez,  Source
carboxypeptidase B2 (plasma, carboxypeptidase U)49750.0160.2654No
161NOGNOG
Entrez,  Source
noggin49950.0160.2649No
162SLIT3SLIT3
Entrez,  Source
slit homolog 3 (Drosophila)50540.0150.2613No
163SERPINA1SERPINA1
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 150980.0150.2589No
164CPN1CPN1
Entrez,  Source
carboxypeptidase N, polypeptide 1, 50kD50990.0150.2598No
165APOA2APOA2
Entrez,  Source
apolipoprotein A-II52140.0140.2519No
166DNASE1DNASE1
Entrez,  Source
deoxyribonuclease I52350.0130.2512No
167PLA2G5PLA2G5
Entrez,  Source
phospholipase A2, group V52370.0130.2519No
168ECM1ECM1
Entrez,  Source
extracellular matrix protein 152980.0130.2481No
169FGF4FGF4
Entrez,  Source
fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene)53720.0120.2432No
170TPT1TPT1
Entrez,  Source
tumor protein, translationally-controlled 154800.0100.2356No
171MEPEMEPE
Entrez,  Source
matrix, extracellular phosphoglycoprotein with ASARM motif (bone)54820.0100.2361No
172ORM1ORM1
Entrez,  Source
orosomucoid 155390.0100.2324No
173LALBALALBA
Entrez,  Source
lactalbumin, alpha-55570.0100.2317No
174YARSYARS
Entrez,  Source
tyrosyl-tRNA synthetase55600.0090.2321No
175SGCESGCE
Entrez,  Source
sarcoglycan, epsilon56080.0090.2290No
176RTN3RTN3
Entrez,  Source
reticulon 356250.0090.2283No
177FGF17FGF17
Entrez,  Source
fibroblast growth factor 1756300.0090.2286No
178TFRCTFRC
Entrez,  Source
transferrin receptor (p90, CD71)56960.0080.2241No
179FGF12FGF12
Entrez,  Source
fibroblast growth factor 1257710.0070.2188No
180LAMA3LAMA3
Entrez,  Source
laminin, alpha 358280.0060.2149No
181ATRNATRN
Entrez,  Source
attractin58690.0060.2122No
182ANGPTL2ANGPTL2
Entrez,  Source
angiopoietin-like 258700.0060.2125No
183SHHSHH
Entrez,  Source
sonic hedgehog homolog (Drosophila)59030.0050.2104No
184SCYE1SCYE1
Entrez,  Source
small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)59240.0050.2092No
185SSTSST
Entrez,  Source
somatostatin59300.0050.2091No
186HPXHPX
Entrez,  Source
hemopexin59640.0050.2069No
187PDZD2PDZD2
Entrez,  Source
PDZ domain containing 259850.0050.2057No
188ANGPT2ANGPT2
Entrez,  Source
angiopoietin 260000.0050.2049No
189CAV3CAV3
Entrez,  Source
caveolin 360310.0040.2028No
190HBEGFHBEGF
Entrez,  Source
heparin-binding EGF-like growth factor62000.0020.1901No
191FXYD6FXYD6
Entrez,  Source
FXYD domain containing ion transport regulator 662280.0020.1881No
192LUMLUM
Entrez,  Source
lumican62500.0020.1867No
193FGF5FGF5
Entrez,  Source
fibroblast growth factor 562860.0010.1841No
194EFEMP2EFEMP2
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 263670.0010.1780No
195PNOCPNOC
Entrez,  Source
prepronociceptin6444-0.0000.1722No
196TCN2TCN2
Entrez,  Source
transcobalamin II; macrocytic anemia6571-0.0020.1626No
197FGF18FGF18
Entrez,  Source
fibroblast growth factor 186630-0.0020.1583No
198FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)6646-0.0020.1573No
199IL18BPIL18BP
Entrez,  Source
interleukin 18 binding protein6672-0.0030.1555No
200COL9A1COL9A1
Entrez,  Source
collagen, type IX, alpha 16699-0.0030.1537No
201C1QAC1QA
Entrez,  Source
complement component 1, q subcomponent, A chain6809-0.0040.1456No
202COL11A1COL11A1
Entrez,  Source
collagen, type XI, alpha 16865-0.0040.1416No
203APCSAPCS
Entrez,  Source
amyloid P component, serum6912-0.0050.1384No
204PLA2G10PLA2G10
Entrez,  Source
phospholipase A2, group X7047-0.0060.1285No
205VWFVWF
Entrez,  Source
von Willebrand factor7140-0.0070.1219No
206APOEAPOE
Entrez,  Source
apolipoprotein E7282-0.0080.1116No
207SOD1SOD1
Entrez,  Source
superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))7350-0.0090.1070No
208TINAGTINAG
Entrez,  Source
tubulointerstitial nephritis antigen7351-0.0090.1075No
209IKIK
Entrez,  Source
IK cytokine, down-regulator of HLA II7356-0.0090.1078No
210EGFL7EGFL7
Entrez,  Source
EGF-like-domain, multiple 77502-0.0100.0973No
211TFF3TFF3
Entrez,  Source
trefoil factor 3 (intestinal)7570-0.0110.0928No
212PTHLHPTHLH
Entrez,  Source
parathyroid hormone-like hormone7588-0.0110.0922No
213CCL20CCL20
Entrez,  Source
chemokine (C-C motif) ligand 207608-0.0120.0914No
214HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 17663-0.0120.0880No
215NPPBNPPB
Entrez,  Source
natriuretic peptide precursor B7667-0.0120.0885No
216MIFMIF
Entrez,  Source
macrophage migration inhibitory factor (glycosylation-inhibiting factor)7726-0.0130.0848No
217SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 17864-0.0140.0752No
218RNH1RNH1
Entrez,  Source
ribonuclease/angiogenin inhibitor 17938-0.0150.0705No
219CTF1CTF1
Entrez,  Source
cardiotrophin 17944-0.0150.0710No
220TFPI2TFPI2
Entrez,  Source
tissue factor pathway inhibitor 28088-0.0170.0611No
221C2C2
Entrez,  Source
complement component 28163-0.0170.0564No
222RNPEPRNPEP
Entrez,  Source
arginyl aminopeptidase (aminopeptidase B)8331-0.0190.0448No
223APOA5APOA5
Entrez,  Source
apolipoprotein A-V8409-0.0200.0400No
224PLUNCPLUNC
Entrez,  Source
palate, lung and nasal epithelium carcinoma associated8437-0.0200.0392No
225LAMB2LAMB2
Entrez,  Source
laminin, beta 2 (laminin S)8617-0.0220.0268No
226INSL3INSL3
Entrez,  Source
insulin-like 3 (Leydig cell)8963-0.0260.0019No
227PNLIPRP1PNLIPRP1
Entrez,  Source
pancreatic lipase-related protein 19006-0.0260.0002No
228IL5IL5
Entrez,  Source
interleukin 5 (colony-stimulating factor, eosinophil)9032-0.026-0.0001No
229PSAPPSAP
Entrez,  Source
prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)9105-0.027-0.0040No
230PROK2PROK2
Entrez,  Source
prokineticin 29205-0.028-0.0099No
231LTBP4LTBP4
Entrez,  Source
latent transforming growth factor beta binding protein 49339-0.029-0.0183No
232PGCPGC
Entrez,  Source
progastricsin (pepsinogen C)9519-0.032-0.0302No
233UTP11LUTP11L
Entrez,  Source
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)9593-0.033-0.0338No
234LGALS8LGALS8
Entrez,  Source
lectin, galactoside-binding, soluble, 8 (galectin 8)9630-0.033-0.0346No
235WFDC2WFDC2
Entrez,  Source
WAP four-disulfide core domain 29661-0.033-0.0349No
236RNASE6RNASE6
Entrez,  Source
ribonuclease, RNase A family, k69735-0.034-0.0384No
237PRSS2PRSS2
Entrez,  Source
protease, serine, 2 (trypsin 2)9857-0.036-0.0455No
238PVRPVR
Entrez,  Source
poliovirus receptor9960-0.037-0.0512No
239SPINT2SPINT2
Entrez,  Source
serine peptidase inhibitor, Kunitz type, 210192-0.039-0.0665No
240SMC3SMC3
Entrez,  Source
structural maintenance of chromosomes 310429-0.042-0.0820No
241SPG7SPG7
Entrez,  Source
spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)10501-0.043-0.0849No
242HDGFHDGF
Entrez,  Source
hepatoma-derived growth factor (high-mobility group protein 1-like)10656-0.046-0.0939No
243IFI30IFI30
Entrez,  Source
interferon, gamma-inducible protein 3010707-0.046-0.0950No
244NPYNPY
Entrez,  Source
neuropeptide Y10886-0.049-0.1057No
245DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)10896-0.050-0.1034No
246CXCL9CXCL9
Entrez,  Source
chemokine (C-X-C motif) ligand 910997-0.051-0.1080No
247APODAPOD
Entrez,  Source
apolipoprotein D11002-0.051-0.1053No
248IL7IL7
Entrez,  Source
interleukin 711170-0.054-0.1148No
249IMPG1IMPG1
Entrez,  Source
interphotoreceptor matrix proteoglycan 111220-0.055-0.1152No
250MMP7MMP7
Entrez,  Source
matrix metallopeptidase 7 (matrilysin, uterine)11231-0.056-0.1127No
251EDN1EDN1
Entrez,  Source
endothelin 111245-0.056-0.1103No
252PPT1PPT1
Entrez,  Source
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)11303-0.057-0.1113No
253CCL7CCL7
Entrez,  Source
chemokine (C-C motif) ligand 711508-0.061-0.1233No
254NUCB1NUCB1
Entrez,  Source
nucleobindin 111522-0.061-0.1207No
255CDH13CDH13
Entrez,  Source
cadherin 13, H-cadherin (heart)11616-0.063-0.1240No
256LAMC1LAMC1
Entrez,  Source
laminin, gamma 1 (formerly LAMB2)11666-0.064-0.1239No
257PGCPPGCP
Entrez,  Source
-11724-0.065-0.1244No
258EGFL6EGFL6
Entrez,  Source
EGF-like-domain, multiple 611727-0.065-0.1206No
259GDF15GDF15
Entrez,  Source
growth differentiation factor 1511771-0.066-0.1200No
260COL5A3COL5A3
Entrez,  Source
collagen, type V, alpha 311947-0.071-0.1291No
261APPAPP
Entrez,  Source
amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)12014-0.073-0.1298No
262IDEIDE
Entrez,  Source
insulin-degrading enzyme12040-0.074-0.1273No
263IL12AIL12A
Entrez,  Source
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)12062-0.075-0.1244No
264CRISP1CRISP1
Entrez,  Source
cysteine-rich secretory protein 112140-0.077-0.1257No
265IL1BIL1B
Entrez,  Source
interleukin 1, beta12206-0.080-0.1259No
266CRISP2CRISP2
Entrez,  Source
cysteine-rich secretory protein 212266-0.082-0.1255No
267COL3A1COL3A1
Entrez,  Source
collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)12298-0.083-0.1229No
268AGGF1AGGF1
Entrez,  Source
angiogenic factor with G patch and FHA domains 112375-0.086-0.1236No
269COL18A1COL18A1
Entrez,  Source
collagen, type XVIII, alpha 112394-0.087-0.1198No
270COMPCOMP
Entrez,  Source
cartilage oligomeric matrix protein12469-0.090-0.1201No
271CCL4CCL4
Entrez,  Source
chemokine (C-C motif) ligand 412509-0.092-0.1176No
272CKLFCKLF
Entrez,  Source
chemokine-like factor12527-0.093-0.1133No
273SCGB1D2SCGB1D2
Entrez,  Source
secretoglobin, family 1D, member 212662-0.100-0.1176No
274TNFRSF11BTNFRSF11B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)12718-0.104-0.1156No
275LGALS3BPLGALS3BP
Entrez,  Source
lectin, galactoside-binding, soluble, 3 binding protein12844-0.115-0.1183No
276CXCL1CXCL1
Entrez,  Source
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)12901-0.121-0.1153No
277MBL2MBL2
Entrez,  Source
mannose-binding lectin (protein C) 2, soluble (opsonic defect)12928-0.124-0.1099No
278ADAMTS5ADAMTS5
Entrez,  Source
ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)12954-0.127-0.1042No
279TGFBITGFBI
Entrez,  Source
transforming growth factor, beta-induced, 68kDa12996-0.131-0.0995No
280CD5LCD5L
Entrez,  Source
CD5 molecule-like13064-0.142-0.0961No
281EFEMP1EFEMP1
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 113077-0.144-0.0884No
282IL15IL15
Entrez,  Source
interleukin 1513126-0.155-0.0828No
283SERPINA7SERPINA7
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 713141-0.159-0.0743No
284MMP9MMP9
Entrez,  Source
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)13151-0.163-0.0653No
285REG3AREG3A
Entrez,  Source
regenerating islet-derived 3 alpha13173-0.171-0.0567No
286MMP11MMP11
Entrez,  Source
matrix metallopeptidase 11 (stromelysin 3)13175-0.172-0.0464No
287IL1AIL1A
Entrez,  Source
interleukin 1, alpha13241-0.218-0.0384No
288CXCL2CXCL2
Entrez,  Source
chemokine (C-X-C motif) ligand 213262-0.231-0.0261No
289CTGFCTGF
Entrez,  Source
connective tissue growth factor13284-0.263-0.0120No
290CCL2CCL2
Entrez,  Source
chemokine (C-C motif) ligand 213292-0.2730.0038No
Table: GSEA details [plain text format]



Fig 2: EXTRACELLULAR_REGION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: EXTRACELLULAR_REGION: Random ES distribution   
Gene set null distribution of ES for EXTRACELLULAR_REGION