Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | FASPATHWAY |
| Enrichment Score (ES) | -0.6702138 |
| Normalized Enrichment Score (NES) | -1.9397225 |
| Nominal p-value | 0.002074689 |
| FDR q-value | 0.07183389 |
| FWER p-Value | 0.565 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 2879 | 0.045 | -0.1759 | No |
| 2 | JUN | JUN Entrez, Source | jun oncogene | 4841 | 0.018 | -0.3069 | No |
| 3 | LMNA | LMNA Entrez, Source | lamin A/C | 6554 | -0.001 | -0.4341 | No |
| 4 | FAF1 | FAF1 Entrez, Source | Fas (TNFRSF6) associated factor 1 | 6769 | -0.004 | -0.4470 | No |
| 5 | DFFB | DFFB Entrez, Source | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 7293 | -0.009 | -0.4786 | No |
| 6 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 7301 | -0.009 | -0.4714 | No |
| 7 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 7416 | -0.010 | -0.4713 | No |
| 8 | CASP7 | CASP7 Entrez, Source | caspase 7, apoptosis-related cysteine peptidase | 8153 | -0.017 | -0.5112 | No |
| 9 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 10273 | -0.040 | -0.6341 | Yes |
| 10 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 10368 | -0.041 | -0.6040 | Yes |
| 11 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 10649 | -0.045 | -0.5843 | Yes |
| 12 | DFFA | DFFA Entrez, Source | DNA fragmentation factor, 45kDa, alpha polypeptide | 11119 | -0.053 | -0.5718 | Yes |
| 13 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 11443 | -0.059 | -0.5428 | Yes |
| 14 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 11474 | -0.060 | -0.4913 | Yes |
| 15 | CFLAR | CFLAR Entrez, Source | CASP8 and FADD-like apoptosis regulator | 11917 | -0.070 | -0.4616 | Yes |
| 16 | FADD | FADD Entrez, Source | Fas (TNFRSF6)-associated via death domain | 12156 | -0.078 | -0.4097 | Yes |
| 17 | PAK2 | PAK2 Entrez, Source | p21 (CDKN1A)-activated kinase 2 | 12379 | -0.086 | -0.3491 | Yes |
| 18 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 12607 | -0.097 | -0.2790 | Yes |
| 19 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 12764 | -0.108 | -0.1940 | Yes |
| 20 | RIPK2 | RIPK2 Entrez, Source | receptor-interacting serine-threonine kinase 2 | 13286 | -0.265 | 0.0042 | Yes |
