Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | FATTY_ACID_METABOLISM |
| Enrichment Score (ES) | 0.49643514 |
| Normalized Enrichment Score (NES) | 1.8236381 |
| Nominal p-value | 0.0020283975 |
| FDR q-value | 0.0804385 |
| FWER p-Value | 0.956 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 7 | 0.362 | 0.0916 | Yes |
| 2 | ACAT2 | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 57 | 0.202 | 0.1393 | Yes |
| 3 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 63 | 0.197 | 0.1890 | Yes |
| 4 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 83 | 0.185 | 0.2347 | Yes |
| 5 | CYP1A1 | CYP1A1 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 1 | 204 | 0.149 | 0.2635 | Yes |
| 6 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 214 | 0.147 | 0.3002 | Yes |
| 7 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 266 | 0.140 | 0.3319 | Yes |
| 8 | CYP3A4 | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 290 | 0.137 | 0.3649 | Yes |
| 9 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 601 | 0.110 | 0.3697 | Yes |
| 10 | FASN | FASN Entrez, Source | fatty acid synthase | 607 | 0.110 | 0.3972 | Yes |
| 11 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 906 | 0.095 | 0.3990 | Yes |
| 12 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 960 | 0.093 | 0.4187 | Yes |
| 13 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 963 | 0.093 | 0.4423 | Yes |
| 14 | LPL | LPL Entrez, Source | lipoprotein lipase | 1116 | 0.087 | 0.4529 | Yes |
| 15 | CYP51A1 | CYP51A1 Entrez, Source | cytochrome P450, family 51, subfamily A, polypeptide 1 | 1345 | 0.079 | 0.4558 | Yes |
| 16 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 1479 | 0.075 | 0.4650 | Yes |
| 17 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 1732 | 0.069 | 0.4635 | Yes |
| 18 | LIPE | LIPE Entrez, Source | lipase, hormone-sensitive | 1739 | 0.069 | 0.4806 | Yes |
| 19 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 1761 | 0.068 | 0.4964 | Yes |
| 20 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 2193 | 0.058 | 0.4787 | No |
| 21 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 2371 | 0.054 | 0.4792 | No |
| 22 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 2873 | 0.045 | 0.4529 | No |
| 23 | PECR | PECR Entrez, Source | peroxisomal trans-2-enoyl-CoA reductase | 3222 | 0.040 | 0.4368 | No |
| 24 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 3886 | 0.030 | 0.3945 | No |
| 25 | CYP2C9 | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 3920 | 0.029 | 0.3995 | No |
| 26 | FAAH | FAAH Entrez, Source | fatty acid amide hydrolase | 3936 | 0.029 | 0.4058 | No |
| 27 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 4497 | 0.022 | 0.3693 | No |
| 28 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 4664 | 0.020 | 0.3618 | No |
| 29 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 5228 | 0.013 | 0.3229 | No |
| 30 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 5527 | 0.010 | 0.3030 | No |
| 31 | CYP1A2 | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 5738 | 0.007 | 0.2891 | No |
| 32 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 5790 | 0.007 | 0.2870 | No |
| 33 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 5819 | 0.007 | 0.2865 | No |
| 34 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 6143 | 0.003 | 0.2630 | No |
| 35 | ACADL | ACADL Entrez, Source | acyl-Coenzyme A dehydrogenase, long chain | 6542 | -0.001 | 0.2334 | No |
| 36 | ACSL5 | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 6561 | -0.002 | 0.2324 | No |
| 37 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 6634 | -0.002 | 0.2276 | No |
| 38 | FABP7 | FABP7 Entrez, Source | fatty acid binding protein 7, brain | 6774 | -0.004 | 0.2181 | No |
| 39 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 7066 | -0.006 | 0.1977 | No |
| 40 | ACOX3 | ACOX3 Entrez, Source | acyl-Coenzyme A oxidase 3, pristanoyl | 7205 | -0.008 | 0.1893 | No |
| 41 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 8031 | -0.016 | 0.1313 | No |
| 42 | CROT | CROT Entrez, Source | carnitine O-octanoyltransferase | 8071 | -0.016 | 0.1325 | No |
| 43 | ABCD2 | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 8162 | -0.017 | 0.1301 | No |
| 44 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 8208 | -0.018 | 0.1313 | No |
| 45 | PECI | PECI Entrez, Source | peroxisomal D3,D2-enoyl-CoA isomerase | 8219 | -0.018 | 0.1351 | No |
| 46 | DCI | DCI Entrez, Source | dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase) | 8556 | -0.021 | 0.1152 | No |
| 47 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 8802 | -0.024 | 0.1029 | No |
| 48 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 9124 | -0.027 | 0.0856 | No |
| 49 | SDS | SDS Entrez, Source | serine dehydratase | 9204 | -0.028 | 0.0868 | No |
| 50 | GNPAT | GNPAT Entrez, Source | glyceronephosphate O-acyltransferase | 10563 | -0.044 | -0.0041 | No |
| 51 | ACOX2 | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 10680 | -0.046 | -0.0012 | No |
| 52 | ACSL4 | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 11316 | -0.057 | -0.0344 | No |
| 53 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 12137 | -0.077 | -0.0765 | No |
| 54 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 12256 | -0.081 | -0.0647 | No |
| 55 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 12333 | -0.084 | -0.0489 | No |
| 56 | ASAH1 | ASAH1 Entrez, Source | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 12784 | -0.110 | -0.0549 | No |
| 57 | ACADSB | ACADSB Entrez, Source | acyl-Coenzyme A dehydrogenase, short/branched chain | 13150 | -0.162 | -0.0411 | No |
| 58 | CYP4B1 | CYP4B1 Entrez, Source | cytochrome P450, family 4, subfamily B, polypeptide 1 | 13244 | -0.218 | 0.0074 | No |
