Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_24h_versus_single_gel_24h.class.cls
#double_gel_24h_versus_single_gel_24h_repos
Phenotypeclass.cls#double_gel_24h_versus_single_gel_24h_repos
Upregulated in classdouble_gel_24h
GeneSetGPCRDB_CLASS_A_RHODOPSIN_LIKE
Enrichment Score (ES)0.43014973
Normalized Enrichment Score (NES)1.8092666
Nominal p-value0.0
FDR q-value0.07738638
FWER p-Value0.975
Table: GSEA Results Summary



Fig 1: Enrichment plot: GPCRDB_CLASS_A_RHODOPSIN_LIKE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NPY1RNPY1R
Entrez,  Source
neuropeptide Y receptor Y11780.1520.0072Yes
2CCBP2CCBP2
Entrez,  Source
chemokine binding protein 21970.1490.0261Yes
3MAS1MAS1
Entrez,  Source
MAS1 oncogene2010.1490.0460Yes
4IL8RAIL8RA
Entrez,  Source
interleukin 8 receptor, alpha2280.1450.0637Yes
5GPR37GPR37
Entrez,  Source
G protein-coupled receptor 37 (endothelin receptor type B-like)2360.1430.0826Yes
6GPR83GPR83
Entrez,  Source
G protein-coupled receptor 832680.1390.0991Yes
7OPRM1OPRM1
Entrez,  Source
opioid receptor, mu 12970.1360.1154Yes
8ADRA1AADRA1A
Entrez,  Source
adrenergic, alpha-1A-, receptor3120.1340.1325Yes
9LHCGRLHCGR
Entrez,  Source
luteinizing hormone/choriogonadotropin receptor3300.1320.1490Yes
10CCKBRCCKBR
Entrez,  Source
cholecystokinin B receptor6320.1080.1409Yes
11TRHRTRHR
Entrez,  Source
thyrotropin-releasing hormone receptor6390.1080.1551Yes
12CXCR3CXCR3
Entrez,  Source
chemokine (C-X-C motif) receptor 36480.1070.1690Yes
13CX3CR1CX3CR1
Entrez,  Source
chemokine (C-X3-C motif) receptor 17680.1010.1737Yes
14AGTRL1AGTRL1
Entrez,  Source
angiotensin II receptor-like 18530.0970.1805Yes
15CCKARCCKAR
Entrez,  Source
cholecystokinin A receptor8990.0950.1900Yes
16DRD3DRD3
Entrez,  Source
dopamine receptor D310480.0900.1910Yes
17CNR1CNR1
Entrez,  Source
cannabinoid receptor 1 (brain)10850.0880.2002Yes
18PPYR1PPYR1
Entrez,  Source
pancreatic polypeptide receptor 111110.0870.2100Yes
19F2RL3F2RL3
Entrez,  Source
coagulation factor II (thrombin) receptor-like 311340.0860.2201Yes
20OPRK1OPRK1
Entrez,  Source
opioid receptor, kappa 111420.0860.2312Yes
21IL8RBIL8RB
Entrez,  Source
interleukin 8 receptor, beta11700.0850.2406Yes
22CCR3CCR3
Entrez,  Source
chemokine (C-C motif) receptor 312270.0830.2476Yes
23OPRD1OPRD1
Entrez,  Source
opioid receptor, delta 112670.0810.2557Yes
24ADRA2AADRA2A
Entrez,  Source
adrenergic, alpha-2A-, receptor13990.0780.2563Yes
25GALR1GALR1
Entrez,  Source
galanin receptor 114950.0750.2593Yes
26CHRM5CHRM5
Entrez,  Source
cholinergic receptor, muscarinic 515580.0730.2645Yes
27CCR6CCR6
Entrez,  Source
chemokine (C-C motif) receptor 615810.0730.2727Yes
28ADORA2AADORA2A
Entrez,  Source
adenosine A2a receptor15860.0730.2823Yes
29PTGFRPTGFR
Entrez,  Source
prostaglandin F receptor (FP)16610.0710.2863Yes
30CMKLR1CMKLR1
Entrez,  Source
chemokine-like receptor 116810.0700.2944Yes
31GPR6GPR6
Entrez,  Source
G protein-coupled receptor 616930.0700.3030Yes
32HTR7HTR7
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)17570.0680.3075Yes
33GPR37L1GPR37L1
Entrez,  Source
G protein-coupled receptor 37 like 117690.0680.3160Yes
34CHRM2CHRM2
Entrez,  Source
cholinergic receptor, muscarinic 217710.0680.3251Yes
35HTR4HTR4
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 417760.0680.3340Yes
36GRPRGRPR
Entrez,  Source
gastrin-releasing peptide receptor18480.0660.3376Yes
37CHRM4CHRM4
Entrez,  Source
cholinergic receptor, muscarinic 418510.0660.3465Yes
38AVPR1BAVPR1B
Entrez,  Source
arginine vasopressin receptor 1B18700.0660.3540Yes
39LTB4RLTB4R
Entrez,  Source
leukotriene B4 receptor19070.0650.3600Yes
40DRD1DRD1
Entrez,  Source
dopamine receptor D120050.0620.3612Yes
41SSTR2SSTR2
Entrez,  Source
somatostatin receptor 220140.0620.3690Yes
42AGTR1AGTR1
Entrez,  Source
angiotensin II receptor, type 120900.0600.3715Yes
43CHRM1CHRM1
Entrez,  Source
cholinergic receptor, muscarinic 120920.0600.3796Yes
44ADRB1ADRB1
Entrez,  Source
adrenergic, beta-1-, receptor21310.0590.3847Yes
45OXTROXTR
Entrez,  Source
oxytocin receptor21840.0580.3887Yes
46EDNRBEDNRB
Entrez,  Source
endothelin receptor type B22520.0560.3912Yes
47PTAFRPTAFR
Entrez,  Source
platelet-activating factor receptor22860.0560.3963Yes
48ADRA2CADRA2C
Entrez,  Source
adrenergic, alpha-2C-, receptor23130.0550.4018Yes
49HTR5AHTR5A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 5A23340.0550.4077Yes
50OPN1SWOPN1SW
Entrez,  Source
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)23600.0540.4132Yes
51HRH2HRH2
Entrez,  Source
histamine receptor H223870.0540.4185Yes
52HTR1AHTR1A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1A25150.0510.4159Yes
53AGTR2AGTR2
Entrez,  Source
angiotensin II receptor, type 225190.0510.4226Yes
54ADRA1DADRA1D
Entrez,  Source
adrenergic, alpha-1D-, receptor25540.0510.4269Yes
55HRH1HRH1
Entrez,  Source
histamine receptor H126010.0500.4301Yes
56HTR2AHTR2A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 2A27000.0480.4292No
57GPR173GPR173
Entrez,  Source
G protein-coupled receptor 17329010.0450.4202No
58HTR6HTR6
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 629400.0440.4233No
59GPR30GPR30
Entrez,  Source
G protein-coupled receptor 3030250.0430.4227No
60GALR3GALR3
Entrez,  Source
galanin receptor 330770.0420.4245No
61SSTR4SSTR4
Entrez,  Source
somatostatin receptor 432230.0400.4189No
62PTGER2PTGER2
Entrez,  Source
prostaglandin E receptor 2 (subtype EP2), 53kDa34780.0360.4045No
63GPR4GPR4
Entrez,  Source
G protein-coupled receptor 434910.0350.4084No
64HCRTR1HCRTR1
Entrez,  Source
hypocretin (orexin) receptor 135890.0340.4057No
65ADORA3ADORA3
Entrez,  Source
adenosine A3 receptor36800.0330.4033No
66HTR2BHTR2B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 2B36840.0330.4075No
67F2RL2F2RL2
Entrez,  Source
coagulation factor II (thrombin) receptor-like 237080.0320.4102No
68GPR44GPR44
Entrez,  Source
G protein-coupled receptor 4437180.0320.4139No
69GPR85GPR85
Entrez,  Source
G protein-coupled receptor 8537300.0320.4174No
70ADRB3ADRB3
Entrez,  Source
adrenergic, beta-3-, receptor37430.0320.4208No
71BLR1BLR1
Entrez,  Source
Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)40450.0280.4018No
72DRD2DRD2
Entrez,  Source
dopamine receptor D240820.0270.4028No
73TBXA2RTBXA2R
Entrez,  Source
thromboxane A2 receptor41130.0270.4042No
74DRD4DRD4
Entrez,  Source
dopamine receptor D442200.0260.3996No
75CCR5CCR5
Entrez,  Source
chemokine (C-C motif) receptor 544840.0220.3827No
76AVPR2AVPR2
Entrez,  Source
arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)44890.0220.3854No
77C3AR1C3AR1
Entrez,  Source
complement component 3a receptor 145270.0210.3855No
78HTR1BHTR1B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1B47670.0190.3700No
79GALTGALT
Entrez,  Source
galactose-1-phosphate uridylyltransferase48370.0180.3673No
80ADORA1ADORA1
Entrez,  Source
adenosine A1 receptor48760.0180.3668No
81DRD5DRD5
Entrez,  Source
dopamine receptor D548950.0170.3678No
82NPY5RNPY5R
Entrez,  Source
neuropeptide Y receptor Y552310.0130.3442No
83CCR2CCR2
Entrez,  Source
chemokine (C-C motif) receptor 253260.0120.3388No
84NMUR2NMUR2
Entrez,  Source
neuromedin U receptor 253670.0120.3373No
85P2RY6P2RY6
Entrez,  Source
pyrimidinergic receptor P2Y, G-protein coupled, 654790.0100.3304No
86GPR50GPR50
Entrez,  Source
G protein-coupled receptor 5056290.0090.3203No
87EDNRAEDNRA
Entrez,  Source
endothelin receptor type A56600.0080.3191No
88BDKRB1BDKRB1
Entrez,  Source
bradykinin receptor B157010.0080.3172No
89RHORHO
Entrez,  Source
rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant)58270.0060.3086No
90HRH3HRH3
Entrez,  Source
histamine receptor H358510.0060.3077No
91NMUR1NMUR1
Entrez,  Source
neuromedin U receptor 163040.0010.2737No
92P2RY2P2RY2
Entrez,  Source
purinergic receptor P2Y, G-protein coupled, 26439-0.0000.2636No
93MC5RMC5R
Entrez,  Source
melanocortin 5 receptor6584-0.0020.2529No
94GPR27GPR27
Entrez,  Source
G protein-coupled receptor 276631-0.0020.2497No
95BDKRB2BDKRB2
Entrez,  Source
bradykinin receptor B27014-0.0060.2216No
96PTGER1PTGER1
Entrez,  Source
prostaglandin E receptor 1 (subtype EP1), 42kDa7055-0.0060.2194No
97CXCR4CXCR4
Entrez,  Source
chemokine (C-X-C motif) receptor 47175-0.0070.2114No
98P2RY12P2RY12
Entrez,  Source
purinergic receptor P2Y, G-protein coupled, 127544-0.0110.1851No
99P2RY14P2RY14
Entrez,  Source
purinergic receptor P2Y, G-protein coupled, 147772-0.0130.1697No
100NMBRNMBR
Entrez,  Source
neuromedin B receptor7890-0.0140.1628No
101GHSRGHSR
Entrez,  Source
growth hormone secretagogue receptor8118-0.0170.1479No
102HCRTR2HCRTR2
Entrez,  Source
hypocretin (orexin) receptor 28532-0.0210.1195No
103NPY2RNPY2R
Entrez,  Source
neuropeptide Y receptor Y28693-0.0230.1105No
104HTR1FHTR1F
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1F8917-0.0250.0971No
105PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)8928-0.0250.0997No
106GALR2GALR2
Entrez,  Source
galanin receptor 29407-0.0300.0677No
107OPRL1OPRL1
Entrez,  Source
opiate receptor-like 19711-0.0340.0494No
108HTR2CHTR2C
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 2C9776-0.0350.0493No
109CHRM3CHRM3
Entrez,  Source
cholinergic receptor, muscarinic 39961-0.0370.0403No
110SSTR1SSTR1
Entrez,  Source
somatostatin receptor 110304-0.0410.0200No
111CCR1CCR1
Entrez,  Source
chemokine (C-C motif) receptor 110676-0.046-0.0019No
112CNR2CNR2
Entrez,  Source
cannabinoid receptor 2 (macrophage)10772-0.048-0.0026No
113NTSR2NTSR2
Entrez,  Source
neurotensin receptor 210880-0.049-0.0040No
114F2RL1F2RL1
Entrez,  Source
coagulation factor II (thrombin) receptor-like 111439-0.059-0.0382No
115MC4RMC4R
Entrez,  Source
melanocortin 4 receptor11608-0.063-0.0424No
116CCR4CCR4
Entrez,  Source
chemokine (C-C motif) receptor 411726-0.065-0.0424No
117ADRA1BADRA1B
Entrez,  Source
adrenergic, alpha-1B-, receptor12029-0.074-0.0552No
118F2RF2R
Entrez,  Source
coagulation factor II (thrombin) receptor12839-0.114-0.1009No
119P2RY1P2RY1
Entrez,  Source
purinergic receptor P2Y, G-protein coupled, 112861-0.116-0.0867No
120AVPR1AAVPR1A
Entrez,  Source
arginine vasopressin receptor 1A13282-0.262-0.0829No
121ADRB2ADRB2
Entrez,  Source
adrenergic, beta-2-, receptor, surface13304-0.298-0.0441No
122ADORA2BADORA2B
Entrez,  Source
adenosine A2b receptor13316-0.3460.0020No
Table: GSEA details [plain text format]



Fig 2: GPCRDB_CLASS_A_RHODOPSIN_LIKE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GPCRDB_CLASS_A_RHODOPSIN_LIKE: Random ES distribution   
Gene set null distribution of ES for GPCRDB_CLASS_A_RHODOPSIN_LIKE