Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_24h_versus_single_gel_24h.class.cls
#double_gel_24h_versus_single_gel_24h_repos
Phenotypeclass.cls#double_gel_24h_versus_single_gel_24h_repos
Upregulated in classdouble_gel_24h
GeneSetGPCRS_CLASS_A_RHODOPSIN_LIKE
Enrichment Score (ES)0.42288437
Normalized Enrichment Score (NES)1.7377917
Nominal p-value0.001980198
FDR q-value0.10898788
FWER p-Value0.997
Table: GSEA Results Summary



Fig 1: Enrichment plot: GPCRS_CLASS_A_RHODOPSIN_LIKE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NPY1RNPY1R
Entrez,  Source
neuropeptide Y receptor Y11780.1520.0101Yes
2CCBP2CCBP2
Entrez,  Source
chemokine binding protein 21970.1490.0318Yes
3MAS1MAS1
Entrez,  Source
MAS1 oncogene2010.1490.0546Yes
4IL8RAIL8RA
Entrez,  Source
interleukin 8 receptor, alpha2280.1450.0749Yes
5GPR37GPR37
Entrez,  Source
G protein-coupled receptor 37 (endothelin receptor type B-like)2360.1430.0965Yes
6OPRM1OPRM1
Entrez,  Source
opioid receptor, mu 12970.1360.1130Yes
7ADRA1AADRA1A
Entrez,  Source
adrenergic, alpha-1A-, receptor3120.1340.1326Yes
8LHCGRLHCGR
Entrez,  Source
luteinizing hormone/choriogonadotropin receptor3300.1320.1517Yes
9CCKBRCCKBR
Entrez,  Source
cholecystokinin B receptor6320.1080.1456Yes
10TRHRTRHR
Entrez,  Source
thyrotropin-releasing hormone receptor6390.1080.1618Yes
11CXCR3CXCR3
Entrez,  Source
chemokine (C-X-C motif) receptor 36480.1070.1778Yes
12CX3CR1CX3CR1
Entrez,  Source
chemokine (C-X3-C motif) receptor 17680.1010.1844Yes
13AGTRL1AGTRL1
Entrez,  Source
angiotensin II receptor-like 18530.0970.1930Yes
14CCKARCCKAR
Entrez,  Source
cholecystokinin A receptor8990.0950.2044Yes
15DRD3DRD3
Entrez,  Source
dopamine receptor D310480.0900.2070Yes
16CNR1CNR1
Entrez,  Source
cannabinoid receptor 1 (brain)10850.0880.2179Yes
17PPYR1PPYR1
Entrez,  Source
pancreatic polypeptide receptor 111110.0870.2294Yes
18OPRK1OPRK1
Entrez,  Source
opioid receptor, kappa 111420.0860.2404Yes
19IL8RBIL8RB
Entrez,  Source
interleukin 8 receptor, beta11700.0850.2515Yes
20CCR3CCR3
Entrez,  Source
chemokine (C-C motif) receptor 312270.0830.2600Yes
21OPRD1OPRD1
Entrez,  Source
opioid receptor, delta 112670.0810.2696Yes
22ADRA2AADRA2A
Entrez,  Source
adrenergic, alpha-2A-, receptor13990.0780.2717Yes
23GALR1GALR1
Entrez,  Source
galanin receptor 114950.0750.2761Yes
24CHRM5CHRM5
Entrez,  Source
cholinergic receptor, muscarinic 515580.0730.2827Yes
25ADORA2AADORA2A
Entrez,  Source
adenosine A2a receptor15860.0730.2919Yes
26PTGFRPTGFR
Entrez,  Source
prostaglandin F receptor (FP)16610.0710.2973Yes
27CMKLR1CMKLR1
Entrez,  Source
chemokine-like receptor 116810.0700.3067Yes
28HTR7HTR7
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)17570.0680.3116Yes
29CHRM2CHRM2
Entrez,  Source
cholinergic receptor, muscarinic 217710.0680.3212Yes
30HTR4HTR4
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 417760.0680.3314Yes
31GRPRGRPR
Entrez,  Source
gastrin-releasing peptide receptor18480.0660.3362Yes
32CHRM4CHRM4
Entrez,  Source
cholinergic receptor, muscarinic 418510.0660.3463Yes
33AVPR1BAVPR1B
Entrez,  Source
arginine vasopressin receptor 1B18700.0660.3551Yes
34LTB4RLTB4R
Entrez,  Source
leukotriene B4 receptor19070.0650.3623Yes
35DRD1DRD1
Entrez,  Source
dopamine receptor D120050.0620.3646Yes
36AGTR1AGTR1
Entrez,  Source
angiotensin II receptor, type 120900.0600.3676Yes
37CHRM1CHRM1
Entrez,  Source
cholinergic receptor, muscarinic 120920.0600.3768Yes
38ADRB1ADRB1
Entrez,  Source
adrenergic, beta-1-, receptor21310.0590.3831Yes
39OXTROXTR
Entrez,  Source
oxytocin receptor21840.0580.3882Yes
40EDNRBEDNRB
Entrez,  Source
endothelin receptor type B22520.0560.3918Yes
41PTAFRPTAFR
Entrez,  Source
platelet-activating factor receptor22860.0560.3979Yes
42ADRA2CADRA2C
Entrez,  Source
adrenergic, alpha-2C-, receptor23130.0550.4045Yes
43HTR5AHTR5A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 5A23340.0550.4114Yes
44HTR1AHTR1A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1A25150.0510.4057Yes
45AGTR2AGTR2
Entrez,  Source
angiotensin II receptor, type 225190.0510.4134Yes
46ADRA1DADRA1D
Entrez,  Source
adrenergic, alpha-1D-, receptor25540.0510.4187Yes
47HRH1HRH1
Entrez,  Source
histamine receptor H126010.0500.4229Yes
48HTR2AHTR2A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 2A27000.0480.4229Yes
49GPR30GPR30
Entrez,  Source
G protein-coupled receptor 3030250.0430.4050No
50GALR3GALR3
Entrez,  Source
galanin receptor 330770.0420.4076No
51PTGER2PTGER2
Entrez,  Source
prostaglandin E receptor 2 (subtype EP2), 53kDa34780.0360.3829No
52GPR4GPR4
Entrez,  Source
G protein-coupled receptor 434910.0350.3874No
53HCRTR1HCRTR1
Entrez,  Source
hypocretin (orexin) receptor 135890.0340.3854No
54ADORA3ADORA3
Entrez,  Source
adenosine A3 receptor36800.0330.3836No
55HTR2BHTR2B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 2B36840.0330.3884No
56F2RL2F2RL2
Entrez,  Source
coagulation factor II (thrombin) receptor-like 237080.0320.3917No
57GPR44GPR44
Entrez,  Source
G protein-coupled receptor 4437180.0320.3960No
58GPR85GPR85
Entrez,  Source
G protein-coupled receptor 8537300.0320.4002No
59ADRB3ADRB3
Entrez,  Source
adrenergic, beta-3-, receptor37430.0320.4042No
60VIPR1VIPR1
Entrez,  Source
vasoactive intestinal peptide receptor 139430.0290.3937No
61BLR1BLR1
Entrez,  Source
Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)40450.0280.3903No
62DRD2DRD2
Entrez,  Source
dopamine receptor D240820.0270.3918No
63TBXA2RTBXA2R
Entrez,  Source
thromboxane A2 receptor41130.0270.3937No
64DRD4DRD4
Entrez,  Source
dopamine receptor D442200.0260.3897No
65CCR5CCR5
Entrez,  Source
chemokine (C-C motif) receptor 544840.0220.3732No
66AVPR2AVPR2
Entrez,  Source
arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)44890.0220.3763No
67C3AR1C3AR1
Entrez,  Source
complement component 3a receptor 145270.0210.3768No
68HTR1BHTR1B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1B47670.0190.3617No
69ADORA1ADORA1
Entrez,  Source
adenosine A1 receptor48760.0180.3563No
70NPY5RNPY5R
Entrez,  Source
neuropeptide Y receptor Y552310.0130.3316No
71CCR2CCR2
Entrez,  Source
chemokine (C-C motif) receptor 253260.0120.3264No
72P2RY6P2RY6
Entrez,  Source
pyrimidinergic receptor P2Y, G-protein coupled, 654790.0100.3165No
73GPR50GPR50
Entrez,  Source
G protein-coupled receptor 5056290.0090.3066No
74PTGER3PTGER3
Entrez,  Source
prostaglandin E receptor 3 (subtype EP3)56340.0090.3077No
75EDNRAEDNRA
Entrez,  Source
endothelin receptor type A56600.0080.3071No
76BDKRB1BDKRB1
Entrez,  Source
bradykinin receptor B157010.0080.3053No
77HRH3HRH3
Entrez,  Source
histamine receptor H358510.0060.2950No
78TSHRTSHR
Entrez,  Source
thyroid stimulating hormone receptor59690.0050.2869No
79P2RY2P2RY2
Entrez,  Source
purinergic receptor P2Y, G-protein coupled, 26439-0.0000.2515No
80GPR27GPR27
Entrez,  Source
G protein-coupled receptor 276631-0.0020.2374No
81BDKRB2BDKRB2
Entrez,  Source
bradykinin receptor B27014-0.0060.2094No
82PTGER1PTGER1
Entrez,  Source
prostaglandin E receptor 1 (subtype EP1), 42kDa7055-0.0060.2074No
83CXCR4CXCR4
Entrez,  Source
chemokine (C-X-C motif) receptor 47175-0.0070.1995No
84P2RY12P2RY12
Entrez,  Source
purinergic receptor P2Y, G-protein coupled, 127544-0.0110.1734No
85NMBRNMBR
Entrez,  Source
neuromedin B receptor7890-0.0140.1496No
86GHSRGHSR
Entrez,  Source
growth hormone secretagogue receptor8118-0.0170.1350No
87HCRTR2HCRTR2
Entrez,  Source
hypocretin (orexin) receptor 28532-0.0210.1071No
88NPY2RNPY2R
Entrez,  Source
neuropeptide Y receptor Y28693-0.0230.0985No
89HTR1FHTR1F
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1F8917-0.0250.0856No
90PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)8928-0.0250.0887No
91GALR2GALR2
Entrez,  Source
galanin receptor 29407-0.0300.0573No
92OPRL1OPRL1
Entrez,  Source
opiate receptor-like 19711-0.0340.0397No
93HTR2CHTR2C
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 2C9776-0.0350.0402No
94CCR1CCR1
Entrez,  Source
chemokine (C-C motif) receptor 110676-0.046-0.0206No
95CNR2CNR2
Entrez,  Source
cannabinoid receptor 2 (macrophage)10772-0.048-0.0205No
96NTSR2NTSR2
Entrez,  Source
neurotensin receptor 210880-0.049-0.0209No
97F2RL1F2RL1
Entrez,  Source
coagulation factor II (thrombin) receptor-like 111439-0.059-0.0539No
98CCR4CCR4
Entrez,  Source
chemokine (C-C motif) receptor 411726-0.065-0.0654No
99ADRA1BADRA1B
Entrez,  Source
adrenergic, alpha-1B-, receptor12029-0.074-0.0768No
100F2RF2R
Entrez,  Source
coagulation factor II (thrombin) receptor12839-0.114-0.1203No
101P2RY1P2RY1
Entrez,  Source
purinergic receptor P2Y, G-protein coupled, 112861-0.116-0.1039No
102AVPR1AAVPR1A
Entrez,  Source
arginine vasopressin receptor 1A13282-0.262-0.0951No
103ADRB2ADRB2
Entrez,  Source
adrenergic, beta-2-, receptor, surface13304-0.298-0.0507No
104ADORA2BADORA2B
Entrez,  Source
adenosine A2b receptor13316-0.3460.0020No
Table: GSEA details [plain text format]



Fig 2: GPCRS_CLASS_A_RHODOPSIN_LIKE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GPCRS_CLASS_A_RHODOPSIN_LIKE: Random ES distribution   
Gene set null distribution of ES for GPCRS_CLASS_A_RHODOPSIN_LIKE