Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_24h_versus_single_gel_24h.class.cls
#double_gel_24h_versus_single_gel_24h_repos
Phenotypeclass.cls#double_gel_24h_versus_single_gel_24h_repos
Upregulated in classdouble_gel_24h
GeneSetG_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY
Enrichment Score (ES)0.35025358
Normalized Enrichment Score (NES)1.6266888
Nominal p-value0.0
FDR q-value0.17801787
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CXCL12CXCL12
Entrez,  Source
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)1050.1750.0034Yes
2GNRHRGNRHR
Entrez,  Source
gonadotropin-releasing hormone receptor1560.1570.0099Yes
3GLP2RGLP2R
Entrez,  Source
glucagon-like peptide 2 receptor1660.1550.0193Yes
4NPY1RNPY1R
Entrez,  Source
neuropeptide Y receptor Y11780.1520.0284Yes
5CCBP2CCBP2
Entrez,  Source
chemokine binding protein 21970.1490.0368Yes
6MAS1MAS1
Entrez,  Source
MAS1 oncogene2010.1490.0463Yes
7IL8RAIL8RA
Entrez,  Source
interleukin 8 receptor, alpha2280.1450.0538Yes
8GPR37GPR37
Entrez,  Source
G protein-coupled receptor 37 (endothelin receptor type B-like)2360.1430.0626Yes
9RGS5RGS5
Entrez,  Source
regulator of G-protein signalling 52830.1370.0681Yes
10OPRM1OPRM1
Entrez,  Source
opioid receptor, mu 12970.1360.0760Yes
11GHRHGHRH
Entrez,  Source
growth hormone releasing hormone3060.1340.0841Yes
12ADRA1AADRA1A
Entrez,  Source
adrenergic, alpha-1A-, receptor3120.1340.0925Yes
13LHCGRLHCGR
Entrez,  Source
luteinizing hormone/choriogonadotropin receptor3300.1320.0998Yes
14RASD1RASD1
Entrez,  Source
RAS, dexamethasone-induced 13570.1290.1062Yes
15ENPP2ENPP2
Entrez,  Source
ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)4290.1230.1088Yes
16CRHR1CRHR1
Entrez,  Source
corticotropin releasing hormone receptor 14730.1200.1134Yes
17RAMP1RAMP1
Entrez,  Source
receptor (calcitonin) activity modifying protein 14850.1190.1203Yes
18APOA1APOA1
Entrez,  Source
apolipoprotein A-I5520.1130.1227Yes
19GLP1RGLP1R
Entrez,  Source
glucagon-like peptide 1 receptor5760.1120.1282Yes
20RGS16RGS16
Entrez,  Source
regulator of G-protein signalling 165840.1110.1350Yes
21GRPGRP
Entrez,  Source
gastrin-releasing peptide5950.1110.1414Yes
22CDK5R1CDK5R1
Entrez,  Source
cyclin-dependent kinase 5, regulatory subunit 1 (p35)6300.1080.1459Yes
23CCKBRCCKBR
Entrez,  Source
cholecystokinin B receptor6320.1080.1529Yes
24TRHRTRHR
Entrez,  Source
thyrotropin-releasing hormone receptor6390.1080.1595Yes
25MCHR1MCHR1
Entrez,  Source
melanin-concentrating hormone receptor 17020.1040.1615Yes
26CRHR2CRHR2
Entrez,  Source
corticotropin releasing hormone receptor 27170.1030.1672Yes
27CX3CR1CX3CR1
Entrez,  Source
chemokine (C-X3-C motif) receptor 17680.1010.1700Yes
28GABRG2GABRG2
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, gamma 28040.0990.1738Yes
29TSHBTSHB
Entrez,  Source
thyroid stimulating hormone, beta8100.0990.1799Yes
30PRLHRPRLHR
Entrez,  Source
prolactin releasing hormone receptor8220.0990.1855Yes
31GRM6GRM6
Entrez,  Source
glutamate receptor, metabotropic 68300.0980.1914Yes
32AGTRL1AGTRL1
Entrez,  Source
angiotensin II receptor-like 18530.0970.1961Yes
33CCKARCCKAR
Entrez,  Source
cholecystokinin A receptor8990.0950.1989Yes
34GNAZGNAZ
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha z polypeptide10360.0900.1944Yes
35DRD3DRD3
Entrez,  Source
dopamine receptor D310480.0900.1994Yes
36CNR1CNR1
Entrez,  Source
cannabinoid receptor 1 (brain)10850.0880.2024Yes
37PTHR1PTHR1
Entrez,  Source
parathyroid hormone receptor 110950.0870.2074Yes
38PPYR1PPYR1
Entrez,  Source
pancreatic polypeptide receptor 111110.0870.2119Yes
39F2RL3F2RL3
Entrez,  Source
coagulation factor II (thrombin) receptor-like 311340.0860.2159Yes
40OPRK1OPRK1
Entrez,  Source
opioid receptor, kappa 111420.0860.2209Yes
41IL8RBIL8RB
Entrez,  Source
interleukin 8 receptor, beta11700.0850.2244Yes
42RGS12RGS12
Entrez,  Source
regulator of G-protein signalling 1211730.0850.2298Yes
43GABRA4GABRA4
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, alpha 411770.0850.2351Yes
44CCR3CCR3
Entrez,  Source
chemokine (C-C motif) receptor 312270.0830.2368Yes
45OPRD1OPRD1
Entrez,  Source
opioid receptor, delta 112670.0810.2391Yes
46GABREGABRE
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, epsilon12850.0810.2431Yes
47TAAR1TAAR1
Entrez,  Source
trace amine associated receptor 113310.0790.2448Yes
48ADRA2AADRA2A
Entrez,  Source
adrenergic, alpha-2A-, receptor13990.0780.2448Yes
49GALR1GALR1
Entrez,  Source
galanin receptor 114950.0750.2424Yes
50CASRCASR
Entrez,  Source
calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism)15430.0740.2436Yes
51NF1NF1
Entrez,  Source
neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)15480.0730.2481Yes
52CHRM5CHRM5
Entrez,  Source
cholinergic receptor, muscarinic 515580.0730.2522Yes
53SPHK1SPHK1
Entrez,  Source
sphingosine kinase 115840.0730.2551Yes
54GABRA1GABRA1
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, alpha 116410.0710.2555Yes
55PTGFRPTGFR
Entrez,  Source
prostaglandin F receptor (FP)16610.0710.2587Yes
56GPR6GPR6
Entrez,  Source
G protein-coupled receptor 616930.0700.2609Yes
57EDN2EDN2
Entrez,  Source
endothelin 217190.0690.2635Yes
58HTR7HTR7
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)17570.0680.2651Yes
59CHRM2CHRM2
Entrez,  Source
cholinergic receptor, muscarinic 217710.0680.2686Yes
60HTR4HTR4
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 417760.0680.2727Yes
61GNG7GNG7
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 717860.0680.2765Yes
62ABCA1ABCA1
Entrez,  Source
ATP-binding cassette, sub-family A (ABC1), member 118320.0670.2774Yes
63OPN1MWOPN1MW
Entrez,  Source
opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)18440.0660.2809Yes
64GRPRGRPR
Entrez,  Source
gastrin-releasing peptide receptor18480.0660.2850Yes
65CHRM4CHRM4
Entrez,  Source
cholinergic receptor, muscarinic 418510.0660.2892Yes
66AVPR1BAVPR1B
Entrez,  Source
arginine vasopressin receptor 1B18700.0660.2921Yes
67LTB4RLTB4R
Entrez,  Source
leukotriene B4 receptor19070.0650.2935Yes
68RGS9RGS9
Entrez,  Source
regulator of G-protein signalling 919470.0640.2947Yes
69DRD1DRD1
Entrez,  Source
dopamine receptor D120050.0620.2944Yes
70SSTR2SSTR2
Entrez,  Source
somatostatin receptor 220140.0620.2979Yes
71AGTR1AGTR1
Entrez,  Source
angiotensin II receptor, type 120900.0600.2961Yes
72CHRM1CHRM1
Entrez,  Source
cholinergic receptor, muscarinic 120920.0600.3000Yes
73TACR3TACR3
Entrez,  Source
tachykinin receptor 321220.0600.3016Yes
74ADRB1ADRB1
Entrez,  Source
adrenergic, beta-1-, receptor21310.0590.3049Yes
75EDNRBEDNRB
Entrez,  Source
endothelin receptor type B22520.0560.2994Yes
76PTAFRPTAFR
Entrez,  Source
platelet-activating factor receptor22860.0560.3005Yes
77ADRA2CADRA2C
Entrez,  Source
adrenergic, alpha-2C-, receptor23130.0550.3022Yes
78GCGGCG
Entrez,  Source
glucagon23190.0550.3054Yes
79GABBR2GABBR2
Entrez,  Source
gamma-aminobutyric acid (GABA) B receptor, 223210.0550.3089Yes
80HTR5AHTR5A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 5A23340.0550.3116Yes
81GPR176GPR176
Entrez,  Source
G protein-coupled receptor 17623540.0540.3137Yes
82HRH2HRH2
Entrez,  Source
histamine receptor H223870.0540.3148Yes
83GHRLGHRL
Entrez,  Source
ghrelin/obestatin preprohormone24170.0530.3160Yes
84PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)24210.0530.3193Yes
85EDG1EDG1
Entrez,  Source
endothelial differentiation, sphingolipid G-protein-coupled receptor, 124630.0520.3196Yes
86C5AR1C5AR1
Entrez,  Source
complement component 5a receptor 124770.0520.3220Yes
87CALCRCALCR
Entrez,  Source
calcitonin receptor24960.0520.3240Yes
88HTR1AHTR1A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1A25150.0510.3259Yes
89SCTRSCTR
Entrez,  Source
secretin receptor25160.0510.3293Yes
90P2RY4P2RY4
Entrez,  Source
pyrimidinergic receptor P2Y, G-protein coupled, 425440.0510.3305Yes
91ADRA1DADRA1D
Entrez,  Source
adrenergic, alpha-1D-, receptor25540.0510.3332Yes
92TAS2R1TAS2R1
Entrez,  Source
taste receptor, type 2, member 125870.0500.3340Yes
93HRH1HRH1
Entrez,  Source
histamine receptor H126010.0500.3362Yes
94MS4A2MS4A2
Entrez,  Source
membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)26080.0500.3390Yes
95RGS4RGS4
Entrez,  Source
regulator of G-protein signalling 426230.0490.3412Yes
96NPFFNPFF
Entrez,  Source
neuropeptide FF-amide peptide precursor26520.0490.3422Yes
97GRM8GRM8
Entrez,  Source
glutamate receptor, metabotropic 826650.0490.3445Yes
98CALCACALCA
Entrez,  Source
calcitonin/calcitonin-related polypeptide, alpha26810.0480.3465Yes
99HTR2AHTR2A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 2A27000.0480.3483Yes
100EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)27160.0480.3503Yes
101CALCRLCALCRL
Entrez,  Source
calcitonin receptor-like28680.0450.3417No
102HTR6HTR6
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 629400.0440.3391No
103GRM4GRM4
Entrez,  Source
glutamate receptor, metabotropic 430140.0430.3363No
104LTB4R2LTB4R2
Entrez,  Source
leukotriene B4 receptor 230560.0420.3360No
105GABRB2GABRB2
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, beta 230710.0420.3376No
106GALR3GALR3
Entrez,  Source
galanin receptor 330770.0420.3400No
107TACR2TACR2
Entrez,  Source
tachykinin receptor 231420.0410.3378No
108CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)31980.0400.3362No
109SSTR4SSTR4
Entrez,  Source
somatostatin receptor 432230.0400.3370No
110PTHPTH
Entrez,  Source
parathyroid hormone32990.0380.3337No
111RGS14RGS14
Entrez,  Source
regulator of G-protein signalling 1434150.0360.3273No
112RIC8BRIC8B
Entrez,  Source
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)34740.0360.3252No
113PTGER2PTGER2
Entrez,  Source
prostaglandin E receptor 2 (subtype EP2), 53kDa34780.0360.3273No
114GPR4GPR4
Entrez,  Source
G protein-coupled receptor 434910.0350.3287No
115HCRTR1HCRTR1
Entrez,  Source
hypocretin (orexin) receptor 135890.0340.3235No
116RGS3RGS3
Entrez,  Source
regulator of G-protein signalling 336160.0340.3237No
117ADORA3ADORA3
Entrez,  Source
adenosine A3 receptor36800.0330.3211No
118HTR2BHTR2B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 2B36840.0330.3230No
119GPR44GPR44
Entrez,  Source
G protein-coupled receptor 4437180.0320.3226No
120ADRB3ADRB3
Entrez,  Source
adrenergic, beta-3-, receptor37430.0320.3228No
121GPR12GPR12
Entrez,  Source
G protein-coupled receptor 1237950.0310.3210No
122GABRR1GABRR1
Entrez,  Source
gamma-aminobutyric acid (GABA) receptor, rho 138630.0300.3178No
123FFAR2FFAR2
Entrez,  Source
free fatty acid receptor 238980.0300.3172No
124VIPR1VIPR1
Entrez,  Source
vasoactive intestinal peptide receptor 139430.0290.3157No
125DRD2DRD2
Entrez,  Source
dopamine receptor D240820.0270.3069No
126TBXA2RTBXA2R
Entrez,  Source
thromboxane A2 receptor41130.0270.3064No
127NPFFR2NPFFR2
Entrez,  Source
neuropeptide FF receptor 241150.0270.3081No
128DRD4DRD4
Entrez,  Source
dopamine receptor D442200.0260.3018No
129DEFB1DEFB1
Entrez,  Source
defensin, beta 142460.0250.3016No
130GLRA1GLRA1
Entrez,  Source
glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)43300.0240.2968No
131WASF2WASF2
Entrez,  Source
WAS protein family, member 244330.0230.2905No
132CCR5CCR5
Entrez,  Source
chemokine (C-C motif) receptor 544840.0220.2881No
133AVPR2AVPR2
Entrez,  Source
arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)44890.0220.2893No
134GRM2GRM2
Entrez,  Source
glutamate receptor, metabotropic 244990.0220.2900No
135GNB3GNB3
Entrez,  Source
guanine nucleotide binding protein (G protein), beta polypeptide 345050.0220.2911No
136GRM5GRM5
Entrez,  Source
glutamate receptor, metabotropic 545090.0220.2922No
137C3AR1C3AR1
Entrez,  Source
complement component 3a receptor 145270.0210.2923No
138GRM1GRM1
Entrez,  Source
glutamate receptor, metabotropic 145580.0210.2914No
139TACR1TACR1
Entrez,  Source
tachykinin receptor 146580.0200.2852No
140APOC3APOC3
Entrez,  Source
apolipoprotein C-III47150.0190.2822No
141ADRA2BADRA2B
Entrez,  Source
adrenergic, alpha-2B-, receptor47510.0190.2808No
142HTR1BHTR1B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1B47670.0190.2808No
143GLRA2GLRA2
Entrez,  Source
glycine receptor, alpha 248350.0180.2769No
144DRD5DRD5
Entrez,  Source
dopamine receptor D548950.0170.2735No
145HOMER3HOMER3
Entrez,  Source
homer homolog 3 (Drosophila)50520.0150.2626No
146CORTCORT
Entrez,  Source
cortistatin51140.0150.2589No
147NPY5RNPY5R
Entrez,  Source
neuropeptide Y receptor Y552310.0130.2509No
148AKAP12AKAP12
Entrez,  Source
A kinase (PRKA) anchor protein (gravin) 1253030.0130.2463No
149CCR2CCR2
Entrez,  Source
chemokine (C-C motif) receptor 253260.0120.2455No
150NMUR2NMUR2
Entrez,  Source
neuromedin U receptor 253670.0120.2432No
151GPR20GPR20
Entrez,  Source
G protein-coupled receptor 2053700.0120.2438No
152P2RY6P2RY6
Entrez,  Source
pyrimidinergic receptor P2Y, G-protein coupled, 654790.0100.2362No
153HOMER1HOMER1
Entrez,  Source
homer homolog 1 (Drosophila)55980.0090.2278No
154GPR50GPR50
Entrez,  Source
G protein-coupled receptor 5056290.0090.2261No
155PTGER3PTGER3
Entrez,  Source
prostaglandin E receptor 3 (subtype EP3)56340.0090.2263No
156EDNRAEDNRA
Entrez,  Source
endothelin receptor type A56600.0080.2250No
157GIPRGIPR
Entrez,  Source
gastric inhibitory polypeptide receptor56780.0080.2242No
158ACRACR
Entrez,  Source
acrosin56830.0080.2244No
159RHORHO
Entrez,  Source
rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant)58270.0060.2139No
160HRH3HRH3
Entrez,  Source
histamine receptor H358510.0060.2126No
161SSTSST
Entrez,  Source
somatostatin59300.0050.2070No
162C3C3
Entrez,  Source
complement component 359620.0050.2049No
163TSHRTSHR
Entrez,  Source
thyroid stimulating hormone receptor59690.0050.2048No
164LANCL1LANCL1
Entrez,  Source
LanC lantibiotic synthetase component C-like 1 (bacterial)60330.0040.2003No
165GRK1GRK1
Entrez,  Source
G protein-coupled receptor kinase 161420.0030.1922No
166NMUR1NMUR1
Entrez,  Source
neuromedin U receptor 163040.0010.1800No
167GHRHRGHRHR
Entrez,  Source
growth hormone releasing hormone receptor63300.0010.1781No
168GABRA3GABRA3
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, alpha 364080.0000.1723No
169P2RY2P2RY2
Entrez,  Source
purinergic receptor P2Y, G-protein coupled, 26439-0.0000.1700No
170GRK4GRK4
Entrez,  Source
G protein-coupled receptor kinase 46507-0.0010.1649No
171MC5RMC5R
Entrez,  Source
melanocortin 5 receptor6584-0.0020.1592No
172GNAI3GNAI3
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 36944-0.0050.1322No
173BDKRB2BDKRB2
Entrez,  Source
bradykinin receptor B27014-0.0060.1273No
174UCNUCN
Entrez,  Source
urocortin7025-0.0060.1269No
175PTGER1PTGER1
Entrez,  Source
prostaglandin E receptor 1 (subtype EP1), 42kDa7055-0.0060.1251No
176CXCR4CXCR4
Entrez,  Source
chemokine (C-X-C motif) receptor 47175-0.0070.1165No
177GPR1GPR1
Entrez,  Source
G protein-coupled receptor 17186-0.0070.1162No
178APOEAPOE
Entrez,  Source
apolipoprotein E7282-0.0080.1095No
179ARHGEF11ARHGEF11
Entrez,  Source
Rho guanine nucleotide exchange factor (GEF) 117349-0.0090.1050No
180PTHLHPTHLH
Entrez,  Source
parathyroid hormone-like hormone7588-0.0110.0876No
181NMBRNMBR
Entrez,  Source
neuromedin B receptor7890-0.0140.0655No
182GHSRGHSR
Entrez,  Source
growth hormone secretagogue receptor8118-0.0170.0493No
183ECEL1ECEL1
Entrez,  Source
endothelin converting enzyme-like 18172-0.0170.0464No
184CCL17CCL17
Entrez,  Source
chemokine (C-C motif) ligand 178478-0.0200.0244No
185HCRTR2HCRTR2
Entrez,  Source
hypocretin (orexin) receptor 28532-0.0210.0218No
186EDG2EDG2
Entrez,  Source
endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 28571-0.0220.0203No
187GLRBGLRB
Entrez,  Source
glycine receptor, beta8597-0.0220.0198No
188GRK5GRK5
Entrez,  Source
G protein-coupled receptor kinase 58649-0.0220.0173No
189NPY2RNPY2R
Entrez,  Source
neuropeptide Y receptor Y28693-0.0230.0155No
190HOMER2HOMER2
Entrez,  Source
homer homolog 2 (Drosophila)8812-0.0240.0081No
191HTR1FHTR1F
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1F8917-0.0250.0018No
192PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)8928-0.0250.0027No
193PTPN6PTPN6
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 69104-0.027-0.0089No
194PLCB2PLCB2
Entrez,  Source
phospholipase C, beta 29169-0.028-0.0120No
195GNA12GNA12
Entrez,  Source
guanine nucleotide binding protein (G protein) alpha 129281-0.029-0.0186No
196GALR2GALR2
Entrez,  Source
galanin receptor 29407-0.030-0.0261No
197PDCPDC
Entrez,  Source
phosducin9436-0.031-0.0263No
198GIT1GIT1
Entrez,  Source
G protein-coupled receptor kinase interactor 19515-0.031-0.0302No
199TBL3TBL3
Entrez,  Source
transducin (beta)-like 39584-0.032-0.0332No
200PICK1PICK1
Entrez,  Source
protein interacting with PRKCA 19587-0.032-0.0313No
201GNB2GNB2
Entrez,  Source
guanine nucleotide binding protein (G protein), beta polypeptide 29604-0.033-0.0304No
202RAPGEF4RAPGEF4
Entrez,  Source
Rap guanine nucleotide exchange factor (GEF) 49637-0.033-0.0306No
203SSTR5SSTR5
Entrez,  Source
somatostatin receptor 59703-0.034-0.0334No
204OPRL1OPRL1
Entrez,  Source
opiate receptor-like 19711-0.034-0.0317No
205ADCYAP1ADCYAP1
Entrez,  Source
adenylate cyclase activating polypeptide 1 (pituitary)9783-0.035-0.0348No
206CHRM3CHRM3
Entrez,  Source
cholinergic receptor, muscarinic 39961-0.037-0.0459No
207RGS2RGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa10143-0.039-0.0572No
208SSTR1SSTR1
Entrez,  Source
somatostatin receptor 110304-0.041-0.0668No
209GNB1GNB1
Entrez,  Source
guanine nucleotide binding protein (G protein), beta polypeptide 110542-0.044-0.0820No
210GRM7GRM7
Entrez,  Source
glutamate receptor, metabotropic 710566-0.044-0.0809No
211GNAI2GNAI2
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 210617-0.045-0.0818No
212CCR1CCR1
Entrez,  Source
chemokine (C-C motif) receptor 110676-0.046-0.0832No
213AKT1AKT1
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 110753-0.047-0.0859No
214CNR2CNR2
Entrez,  Source
cannabinoid receptor 2 (macrophage)10772-0.048-0.0842No
215GIT2GIT2
Entrez,  Source
G protein-coupled receptor kinase interactor 210815-0.048-0.0842No
216GNAQGNAQ
Entrez,  Source
guanine nucleotide binding protein (G protein), q polypeptide10825-0.048-0.0817No
217NPYNPY
Entrez,  Source
neuropeptide Y10886-0.049-0.0831No
218CXCL9CXCL9
Entrez,  Source
chemokine (C-X-C motif) ligand 910997-0.051-0.0882No
219GPRC5CGPRC5C
Entrez,  Source
G protein-coupled receptor, family C, group 5, member C11018-0.051-0.0864No
220CAP1CAP1
Entrez,  Source
CAP, adenylate cyclase-associated protein 1 (yeast)11031-0.051-0.0839No
221GCGRGCGR
Entrez,  Source
glucagon receptor11253-0.056-0.0971No
222F2RL1F2RL1
Entrez,  Source
coagulation factor II (thrombin) receptor-like 111439-0.059-0.1074No
223VIPVIP
Entrez,  Source
vasoactive intestinal peptide11599-0.062-0.1154No
224MC4RMC4R
Entrez,  Source
melanocortin 4 receptor11608-0.063-0.1119No
225PPAP2APPAP2A
Entrez,  Source
phosphatidic acid phosphatase type 2A11707-0.065-0.1152No
226RGS1RGS1
Entrez,  Source
regulator of G-protein signalling 111849-0.069-0.1215No
227GABBR1GABBR1
Entrez,  Source
gamma-aminobutyric acid (GABA) B receptor, 111865-0.069-0.1181No
228ADRA1BADRA1B
Entrez,  Source
adrenergic, alpha-1B-, receptor12029-0.074-0.1258No
229RGS19RGS19
Entrez,  Source
regulator of G-protein signalling 1912073-0.075-0.1241No
230GAP43GAP43
Entrez,  Source
growth associated protein 4312439-0.088-0.1462No
231GNASGNAS
Entrez,  Source
GNAS complex locus12462-0.089-0.1421No
232GPR39GPR39
Entrez,  Source
G protein-coupled receptor 3912485-0.090-0.1378No
233GNA15GNA15
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)12502-0.092-0.1331No
234GRK6GRK6
Entrez,  Source
G protein-coupled receptor kinase 612510-0.092-0.1276No
235PIK3CBPIK3CB
Entrez,  Source
phosphoinositide-3-kinase, catalytic, beta polypeptide12588-0.096-0.1272No
236GPR19GPR19
Entrez,  Source
G protein-coupled receptor 1912821-0.113-0.1376No
237CCL3CCL3
Entrez,  Source
chemokine (C-C motif) ligand 312853-0.115-0.1324No
238CALM3CALM3
Entrez,  Source
calmodulin 3 (phosphorylase kinase, delta)12855-0.115-0.1250No
239P2RY1P2RY1
Entrez,  Source
purinergic receptor P2Y, G-protein coupled, 112861-0.116-0.1177No
240CXCL1CXCL1
Entrez,  Source
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)12901-0.121-0.1128No
241BCAR1BCAR1
Entrez,  Source
breast cancer anti-estrogen resistance 112923-0.123-0.1063No
242DEFB4DEFB4
Entrez,  Source
defensin, beta 413093-0.149-0.1095No
243GRM3GRM3
Entrez,  Source
glutamate receptor, metabotropic 313128-0.156-0.1019No
244PLCE1PLCE1
Entrez,  Source
phospholipase C, epsilon 113205-0.194-0.0951No
245EDG7EDG7
Entrez,  Source
endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 713222-0.206-0.0828No
246EDG5EDG5
Entrez,  Source
endothelial differentiation, sphingolipid G-protein-coupled receptor, 513254-0.222-0.0706No
247AVPR1AAVPR1A
Entrez,  Source
arginine vasopressin receptor 1A13282-0.262-0.0556No
248CCL2CCL2
Entrez,  Source
chemokine (C-C motif) ligand 213292-0.273-0.0384No
249ADRB2ADRB2
Entrez,  Source
adrenergic, beta-2-, receptor, surface13304-0.298-0.0198No
250ADORA2BADORA2B
Entrez,  Source
adenosine A2b receptor13316-0.3460.0020No
Table: GSEA details [plain text format]



Fig 2: G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY: Random ES distribution   
Gene set null distribution of ES for G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY