Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | HCC_SURVIVAL_GOOD_VS_POOR_UP |
| Enrichment Score (ES) | 0.37974516 |
| Normalized Enrichment Score (NES) | 1.5429615 |
| Nominal p-value | 0.009689922 |
| FDR q-value | 0.23698215 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 7 | 0.362 | 0.0598 | Yes |
| 2 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 14 | 0.295 | 0.1086 | Yes |
| 3 | C4BPB | C4BPB Entrez, Source | complement component 4 binding protein, beta | 18 | 0.268 | 0.1531 | Yes |
| 4 | ABCG8 | ABCG8 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2) | 51 | 0.210 | 0.1858 | Yes |
| 5 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 59 | 0.201 | 0.2187 | Yes |
| 6 | LPIN1 | LPIN1 Entrez, Source | lipin 1 | 182 | 0.151 | 0.2348 | Yes |
| 7 | AQP9 | AQP9 Entrez, Source | aquaporin 9 | 232 | 0.144 | 0.2551 | Yes |
| 8 | CYP3A4 | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 290 | 0.137 | 0.2735 | Yes |
| 9 | SULT2A1 | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 367 | 0.128 | 0.2892 | Yes |
| 10 | PC | PC Entrez, Source | pyruvate carboxylase | 403 | 0.125 | 0.3075 | Yes |
| 11 | ABCG5 | ABCG5 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1) | 497 | 0.118 | 0.3201 | Yes |
| 12 | IL6R | IL6R Entrez, Source | interleukin 6 receptor | 695 | 0.104 | 0.3226 | Yes |
| 13 | SERPIND1 | SERPIND1 Entrez, Source | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 812 | 0.099 | 0.3304 | Yes |
| 14 | WNT11 | WNT11 Entrez, Source | wingless-type MMTV integration site family, member 11 | 860 | 0.097 | 0.3430 | Yes |
| 15 | ZP3 | ZP3 Entrez, Source | zona pellucida glycoprotein 3 (sperm receptor) | 867 | 0.097 | 0.3587 | Yes |
| 16 | INSIG1 | INSIG1 Entrez, Source | insulin induced gene 1 | 978 | 0.092 | 0.3658 | Yes |
| 17 | CDO1 | CDO1 Entrez, Source | cysteine dioxygenase, type I | 996 | 0.091 | 0.3797 | Yes |
| 18 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 1252 | 0.082 | 0.3742 | No |
| 19 | PKLR | PKLR Entrez, Source | pyruvate kinase, liver and RBC | 1449 | 0.076 | 0.3721 | No |
| 20 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 1548 | 0.073 | 0.3769 | No |
| 21 | CES1 | CES1 Entrez, Source | carboxylesterase 1 (monocyte/macrophage serine esterase 1) | 2057 | 0.061 | 0.3488 | No |
| 22 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 2152 | 0.059 | 0.3515 | No |
| 23 | DCXR | DCXR Entrez, Source | dicarbonyl/L-xylulose reductase | 2731 | 0.047 | 0.3158 | No |
| 24 | KHK | KHK Entrez, Source | ketohexokinase (fructokinase) | 2773 | 0.047 | 0.3204 | No |
| 25 | ASGR1 | ASGR1 Entrez, Source | asialoglycoprotein receptor 1 | 3023 | 0.043 | 0.3088 | No |
| 26 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 3148 | 0.041 | 0.3062 | No |
| 27 | SERPINC1 | SERPINC1 Entrez, Source | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 3303 | 0.038 | 0.3010 | No |
| 28 | MVK | MVK Entrez, Source | mevalonate kinase (mevalonic aciduria) | 3344 | 0.038 | 0.3042 | No |
| 29 | SEC14L2 | SEC14L2 Entrez, Source | SEC14-like 2 (S. cerevisiae) | 3545 | 0.035 | 0.2949 | No |
| 30 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 3698 | 0.033 | 0.2889 | No |
| 31 | SLC38A3 | SLC38A3 Entrez, Source | solute carrier family 38, member 3 | 3728 | 0.032 | 0.2920 | No |
| 32 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 4085 | 0.027 | 0.2697 | No |
| 33 | F10 | F10 Entrez, Source | coagulation factor X | 4278 | 0.025 | 0.2594 | No |
| 34 | SLC6A12 | SLC6A12 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 | 4308 | 0.025 | 0.2613 | No |
| 35 | MYRIP | MYRIP Entrez, Source | myosin VIIA and Rab interacting protein | 4486 | 0.022 | 0.2516 | No |
| 36 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 4497 | 0.022 | 0.2545 | No |
| 37 | AMACR | AMACR Entrez, Source | alpha-methylacyl-CoA racemase | 4628 | 0.020 | 0.2481 | No |
| 38 | STARD10 | STARD10 Entrez, Source | START domain containing 10 | 4710 | 0.019 | 0.2452 | No |
| 39 | APOC3 | APOC3 Entrez, Source | apolipoprotein C-III | 4715 | 0.019 | 0.2482 | No |
| 40 | ACF | ACF Entrez, Source | - | 4930 | 0.017 | 0.2348 | No |
| 41 | CPB2 | CPB2 Entrez, Source | carboxypeptidase B2 (plasma, carboxypeptidase U) | 4975 | 0.016 | 0.2342 | No |
| 42 | MUCDHL | MUCDHL Entrez, Source | mucin and cadherin-like | 5169 | 0.014 | 0.2220 | No |
| 43 | NDRG2 | NDRG2 Entrez, Source | NDRG family member 2 | 5272 | 0.013 | 0.2165 | No |
| 44 | ITPR2 | ITPR2 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 2 | 5533 | 0.010 | 0.1985 | No |
| 45 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 5731 | 0.008 | 0.1849 | No |
| 46 | SERPING1 | SERPING1 Entrez, Source | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | 5808 | 0.007 | 0.1802 | No |
| 47 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 5819 | 0.007 | 0.1806 | No |
| 48 | PCYT2 | PCYT2 Entrez, Source | phosphate cytidylyltransferase 2, ethanolamine | 5921 | 0.005 | 0.1738 | No |
| 49 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 6143 | 0.003 | 0.1577 | No |
| 50 | AR | AR Entrez, Source | androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) | 6572 | -0.002 | 0.1257 | No |
| 51 | ENPP5 | ENPP5 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative function) | 6579 | -0.002 | 0.1255 | No |
| 52 | HADH2 | HADH2 Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase, type II | 6668 | -0.003 | 0.1193 | No |
| 53 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 6761 | -0.003 | 0.1129 | No |
| 54 | APCS | APCS Entrez, Source | amyloid P component, serum | 6912 | -0.005 | 0.1024 | No |
| 55 | MST1 | MST1 Entrez, Source | macrophage stimulating 1 (hepatocyte growth factor-like) | 7046 | -0.006 | 0.0934 | No |
| 56 | MASP2 | MASP2 Entrez, Source | mannan-binding lectin serine peptidase 2 | 7091 | -0.006 | 0.0911 | No |
| 57 | GJB1 | GJB1 Entrez, Source | gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked) | 7457 | -0.010 | 0.0652 | No |
| 58 | F12 | F12 Entrez, Source | coagulation factor XII (Hageman factor) | 7631 | -0.012 | 0.0542 | No |
| 59 | CABC1 | CABC1 Entrez, Source | chaperone, ABC1 activity of bc1 complex homolog (S. pombe) | 7823 | -0.014 | 0.0420 | No |
| 60 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 7864 | -0.014 | 0.0414 | No |
| 61 | AMT | AMT Entrez, Source | aminomethyltransferase | 7887 | -0.014 | 0.0421 | No |
| 62 | ABHD6 | ABHD6 Entrez, Source | abhydrolase domain containing 6 | 7959 | -0.015 | 0.0393 | No |
| 63 | EGLN2 | EGLN2 Entrez, Source | egl nine homolog 2 (C. elegans) | 8020 | -0.016 | 0.0374 | No |
| 64 | C2 | C2 Entrez, Source | complement component 2 | 8163 | -0.017 | 0.0296 | No |
| 65 | PRDX6 | PRDX6 Entrez, Source | peroxiredoxin 6 | 8269 | -0.018 | 0.0247 | No |
| 66 | INSR | INSR Entrez, Source | insulin receptor | 8403 | -0.020 | 0.0180 | No |
| 67 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 8409 | -0.020 | 0.0209 | No |
| 68 | PCCB | PCCB Entrez, Source | propionyl Coenzyme A carboxylase, beta polypeptide | 8561 | -0.021 | 0.0130 | No |
| 69 | MRPL46 | MRPL46 Entrez, Source | mitochondrial ribosomal protein L46 | 8624 | -0.022 | 0.0120 | No |
| 70 | CABIN1 | CABIN1 Entrez, Source | - | 9092 | -0.027 | -0.0187 | No |
| 71 | SLC25A10 | SLC25A10 Entrez, Source | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 9394 | -0.030 | -0.0364 | No |
| 72 | MSRA | MSRA Entrez, Source | methionine sulfoxide reductase A | 9489 | -0.031 | -0.0383 | No |
| 73 | SGPL1 | SGPL1 Entrez, Source | sphingosine-1-phosphate lyase 1 | 9899 | -0.036 | -0.0632 | No |
| 74 | CRAT | CRAT Entrez, Source | carnitine acetyltransferase | 10089 | -0.038 | -0.0711 | No |
| 75 | TTPA | TTPA Entrez, Source | tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency) | 10180 | -0.039 | -0.0713 | No |
| 76 | HAGH | HAGH Entrez, Source | hydroxyacylglutathione hydrolase | 10339 | -0.041 | -0.0764 | No |
| 77 | NDUFS2 | NDUFS2 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 10644 | -0.045 | -0.0918 | No |
| 78 | ACOX2 | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 10680 | -0.046 | -0.0867 | No |
| 79 | EPHX1 | EPHX1 Entrez, Source | epoxide hydrolase 1, microsomal (xenobiotic) | 10955 | -0.050 | -0.0990 | No |
| 80 | CES2 | CES2 Entrez, Source | carboxylesterase 2 (intestine, liver) | 10980 | -0.051 | -0.0924 | No |
| 81 | MPDZ | MPDZ Entrez, Source | multiple PDZ domain protein | 11206 | -0.055 | -0.1002 | No |
| 82 | DPYS | DPYS Entrez, Source | dihydropyrimidinase | 11440 | -0.059 | -0.1079 | No |
| 83 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 11707 | -0.065 | -0.1171 | No |
| 84 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 11730 | -0.065 | -0.1079 | No |
| 85 | CRYL1 | CRYL1 Entrez, Source | crystallin, lambda 1 | 11907 | -0.070 | -0.1095 | No |
| 86 | GLYAT | GLYAT Entrez, Source | glycine-N-acyltransferase | 11991 | -0.073 | -0.1036 | No |
| 87 | SLC2A2 | SLC2A2 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 2 | 12210 | -0.080 | -0.1068 | No |
| 88 | KLK3 | KLK3 Entrez, Source | kallikrein 3, (prostate specific antigen) | 12475 | -0.090 | -0.1117 | No |
| 89 | PAH | PAH Entrez, Source | phenylalanine hydroxylase | 12643 | -0.099 | -0.1078 | No |
| 90 | FMO3 | FMO3 Entrez, Source | flavin containing monooxygenase 3 | 12657 | -0.100 | -0.0922 | No |
| 91 | IVD | IVD Entrez, Source | isovaleryl Coenzyme A dehydrogenase | 12683 | -0.102 | -0.0771 | No |
| 92 | ABCC2 | ABCC2 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 12994 | -0.131 | -0.0786 | No |
| 93 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13176 | -0.172 | -0.0635 | No |
| 94 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 13197 | -0.186 | -0.0339 | No |
| 95 | CES3 | CES3 Entrez, Source | carboxylesterase 3 (brain) | 13290 | -0.269 | 0.0039 | No |
