Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | HINATA_NFKB_UP |
| Enrichment Score (ES) | -0.45132843 |
| Normalized Enrichment Score (NES) | -1.7540871 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.13515183 |
| FWER p-Value | 0.994 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 236 | 0.143 | 0.0095 | No |
| 2 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 347 | 0.130 | 0.0260 | No |
| 3 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 491 | 0.118 | 0.0378 | No |
| 4 | TNFAIP6 | TNFAIP6 Entrez, Source | tumor necrosis factor, alpha-induced protein 6 | 543 | 0.114 | 0.0557 | No |
| 5 | BMP2 | BMP2 Entrez, Source | bone morphogenetic protein 2 | 547 | 0.114 | 0.0772 | No |
| 6 | IER3 | IER3 Entrez, Source | immediate early response 3 | 890 | 0.096 | 0.0697 | No |
| 7 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 1076 | 0.088 | 0.0726 | No |
| 8 | CDH3 | CDH3 Entrez, Source | cadherin 3, type 1, P-cadherin (placental) | 1246 | 0.082 | 0.0755 | No |
| 9 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 1805 | 0.067 | 0.0462 | No |
| 10 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 1933 | 0.064 | 0.0488 | No |
| 11 | NPR1 | NPR1 Entrez, Source | natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) | 2186 | 0.058 | 0.0409 | No |
| 12 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 2253 | 0.056 | 0.0466 | No |
| 13 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 2302 | 0.055 | 0.0536 | No |
| 14 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 2879 | 0.045 | 0.0187 | No |
| 15 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3035 | 0.043 | 0.0151 | No |
| 16 | RABEP1 | RABEP1 Entrez, Source | rabaptin, RAB GTPase binding effector protein 1 | 3117 | 0.041 | 0.0169 | No |
| 17 | WNT5A | WNT5A Entrez, Source | wingless-type MMTV integration site family, member 5A | 3195 | 0.040 | 0.0187 | No |
| 18 | IL1RN | IL1RN Entrez, Source | interleukin 1 receptor antagonist | 3400 | 0.037 | 0.0104 | No |
| 19 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 3481 | 0.035 | 0.0111 | No |
| 20 | MAP1B | MAP1B Entrez, Source | microtubule-associated protein 1B | 3700 | 0.033 | 0.0009 | No |
| 21 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 3714 | 0.032 | 0.0061 | No |
| 22 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 3877 | 0.030 | -0.0004 | No |
| 23 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 4601 | 0.021 | -0.0510 | No |
| 24 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 4663 | 0.020 | -0.0518 | No |
| 25 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 5422 | 0.011 | -0.1068 | No |
| 26 | CYP27B1 | CYP27B1 Entrez, Source | cytochrome P450, family 27, subfamily B, polypeptide 1 | 5553 | 0.010 | -0.1148 | No |
| 27 | ESM1 | ESM1 Entrez, Source | endothelial cell-specific molecule 1 | 5998 | 0.005 | -0.1474 | No |
| 28 | FN1 | FN1 Entrez, Source | fibronectin 1 | 6064 | 0.004 | -0.1515 | No |
| 29 | CSF2 | CSF2 Entrez, Source | colony stimulating factor 2 (granulocyte-macrophage) | 6070 | 0.004 | -0.1511 | No |
| 30 | FGF5 | FGF5 Entrez, Source | fibroblast growth factor 5 | 6286 | 0.001 | -0.1671 | No |
| 31 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 6376 | 0.000 | -0.1737 | No |
| 32 | CTSE | CTSE Entrez, Source | cathepsin E | 6446 | -0.000 | -0.1789 | No |
| 33 | STAT5A | STAT5A Entrez, Source | signal transducer and activator of transcription 5A | 6535 | -0.001 | -0.1853 | No |
| 34 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6594 | -0.002 | -0.1893 | No |
| 35 | PNRC1 | PNRC1 Entrez, Source | proline-rich nuclear receptor coactivator 1 | 7030 | -0.006 | -0.2209 | No |
| 36 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 7114 | -0.007 | -0.2259 | No |
| 37 | MAPK9 | MAPK9 Entrez, Source | mitogen-activated protein kinase 9 | 7208 | -0.008 | -0.2314 | No |
| 38 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 7260 | -0.008 | -0.2337 | No |
| 39 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7350 | -0.009 | -0.2387 | No |
| 40 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 7608 | -0.012 | -0.2559 | No |
| 41 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 7682 | -0.012 | -0.2590 | No |
| 42 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 8457 | -0.020 | -0.3135 | No |
| 43 | ITGB6 | ITGB6 Entrez, Source | integrin, beta 6 | 8714 | -0.023 | -0.3284 | No |
| 44 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 8761 | -0.023 | -0.3274 | No |
| 45 | AP2B1 | AP2B1 Entrez, Source | adaptor-related protein complex 2, beta 1 subunit | 8860 | -0.025 | -0.3301 | No |
| 46 | HGFAC | HGFAC Entrez, Source | HGF activator | 8869 | -0.025 | -0.3260 | No |
| 47 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 9174 | -0.028 | -0.3436 | No |
| 48 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 9619 | -0.033 | -0.3708 | No |
| 49 | SLC7A2 | SLC7A2 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 9632 | -0.033 | -0.3654 | No |
| 50 | WFDC2 | WFDC2 Entrez, Source | WAP four-disulfide core domain 2 | 9661 | -0.033 | -0.3611 | No |
| 51 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 10033 | -0.038 | -0.3819 | No |
| 52 | GTF2H4 | GTF2H4 Entrez, Source | general transcription factor IIH, polypeptide 4, 52kDa | 10115 | -0.039 | -0.3807 | No |
| 53 | BCL2A1 | BCL2A1 Entrez, Source | BCL2-related protein A1 | 10553 | -0.044 | -0.4052 | No |
| 54 | ABCC1 | ABCC1 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 10882 | -0.049 | -0.4205 | No |
| 55 | SERPINB2 | SERPINB2 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 11162 | -0.054 | -0.4312 | No |
| 56 | SELE | SELE Entrez, Source | selectin E (endothelial adhesion molecule 1) | 11163 | -0.054 | -0.4209 | No |
| 57 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 11245 | -0.056 | -0.4164 | No |
| 58 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 11710 | -0.065 | -0.4389 | Yes |
| 59 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 11718 | -0.065 | -0.4270 | Yes |
| 60 | CD9 | CD9 Entrez, Source | CD9 molecule | 11802 | -0.067 | -0.4205 | Yes |
| 61 | MAP2K3 | MAP2K3 Entrez, Source | mitogen-activated protein kinase kinase 3 | 11810 | -0.068 | -0.4081 | Yes |
| 62 | GABBR1 | GABBR1 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 1 | 11865 | -0.069 | -0.3990 | Yes |
| 63 | CFLAR | CFLAR Entrez, Source | CASP8 and FADD-like apoptosis regulator | 11917 | -0.070 | -0.3895 | Yes |
| 64 | IL1B | IL1B Entrez, Source | interleukin 1, beta | 12206 | -0.080 | -0.3960 | Yes |
| 65 | NFKB2 | NFKB2 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 12794 | -0.110 | -0.4193 | Yes |
| 66 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 12901 | -0.121 | -0.4042 | Yes |
| 67 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 13097 | -0.150 | -0.3903 | Yes |
| 68 | IL15 | IL15 Entrez, Source | interleukin 15 | 13126 | -0.155 | -0.3628 | Yes |
| 69 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 13151 | -0.163 | -0.3336 | Yes |
| 70 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13214 | -0.201 | -0.3000 | Yes |
| 71 | IL1A | IL1A Entrez, Source | interleukin 1, alpha | 13241 | -0.218 | -0.2604 | Yes |
| 72 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13262 | -0.231 | -0.2179 | Yes |
| 73 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 13267 | -0.235 | -0.1733 | Yes |
| 74 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13292 | -0.273 | -0.1231 | Yes |
| 75 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13310 | -0.321 | -0.0631 | Yes |
| 76 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13315 | -0.343 | 0.0020 | Yes |
