Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | HIVNEFPATHWAY |
| Enrichment Score (ES) | -0.61936396 |
| Normalized Enrichment Score (NES) | -2.111141 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0198879 |
| FWER p-Value | 0.07 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 2879 | 0.045 | -0.1944 | No |
| 2 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 3475 | 0.036 | -0.2218 | No |
| 3 | BIRC2 | BIRC2 Entrez, Source | baculoviral IAP repeat-containing 2 | 5286 | 0.013 | -0.3516 | No |
| 4 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 5475 | 0.010 | -0.3606 | No |
| 5 | CDC2L1 | CDC2L1 Entrez, Source | cell division cycle 2-like 1 (PITSLRE proteins) | 6514 | -0.001 | -0.4382 | No |
| 6 | LMNA | LMNA Entrez, Source | lamin A/C | 6554 | -0.001 | -0.4404 | No |
| 7 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 6812 | -0.004 | -0.4579 | No |
| 8 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 7260 | -0.008 | -0.4874 | No |
| 9 | DFFB | DFFB Entrez, Source | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 7293 | -0.009 | -0.4857 | No |
| 10 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 7301 | -0.009 | -0.4820 | No |
| 11 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 7500 | -0.010 | -0.4917 | No |
| 12 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 7818 | -0.014 | -0.5088 | No |
| 13 | CASP7 | CASP7 Entrez, Source | caspase 7, apoptosis-related cysteine peptidase | 8153 | -0.017 | -0.5256 | No |
| 14 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 8457 | -0.020 | -0.5384 | No |
| 15 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 8779 | -0.024 | -0.5510 | No |
| 16 | BIRC4 | BIRC4 Entrez, Source | baculoviral IAP repeat-containing 4 | 8879 | -0.025 | -0.5463 | No |
| 17 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 9040 | -0.026 | -0.5454 | No |
| 18 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 9174 | -0.028 | -0.5418 | No |
| 19 | BAG4 | BAG4 Entrez, Source | BCL2-associated athanogene 4 | 10207 | -0.040 | -0.6000 | Yes |
| 20 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 10273 | -0.040 | -0.5852 | Yes |
| 21 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 10368 | -0.041 | -0.5719 | Yes |
| 22 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 10649 | -0.045 | -0.5707 | Yes |
| 23 | DFFA | DFFA Entrez, Source | DNA fragmentation factor, 45kDa, alpha polypeptide | 11119 | -0.053 | -0.5800 | Yes |
| 24 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 11353 | -0.058 | -0.5692 | Yes |
| 25 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 11443 | -0.059 | -0.5468 | Yes |
| 26 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 11467 | -0.060 | -0.5192 | Yes |
| 27 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 11474 | -0.060 | -0.4903 | Yes |
| 28 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 11607 | -0.063 | -0.4696 | Yes |
| 29 | CFLAR | CFLAR Entrez, Source | CASP8 and FADD-like apoptosis regulator | 11917 | -0.070 | -0.4585 | Yes |
| 30 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 12004 | -0.073 | -0.4292 | Yes |
| 31 | BID | BID Entrez, Source | BH3 interacting domain death agonist | 12134 | -0.077 | -0.4012 | Yes |
| 32 | FADD | FADD Entrez, Source | Fas (TNFRSF6)-associated via death domain | 12156 | -0.078 | -0.3647 | Yes |
| 33 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12178 | -0.079 | -0.3277 | Yes |
| 34 | PAK2 | PAK2 Entrez, Source | p21 (CDKN1A)-activated kinase 2 | 12379 | -0.086 | -0.3006 | Yes |
| 35 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 12607 | -0.097 | -0.2701 | Yes |
| 36 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 12964 | -0.127 | -0.2346 | Yes |
| 37 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 13032 | -0.136 | -0.1729 | Yes |
| 38 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 13071 | -0.143 | -0.1056 | Yes |
| 39 | APAF1 | APAF1 Entrez, Source | apoptotic peptidase activating factor | 13280 | -0.257 | 0.0047 | Yes |
