Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | HSA04520_ADHERENS_JUNCTION |
| Enrichment Score (ES) | -0.41971892 |
| Normalized Enrichment Score (NES) | -1.4897195 |
| Nominal p-value | 0.03420523 |
| FDR q-value | 0.27745324 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 76 | 0.189 | 0.0628 | No |
| 2 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 179 | 0.152 | 0.1105 | No |
| 3 | SRC | SRC Entrez, Source | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 729 | 0.103 | 0.1066 | No |
| 4 | PARD3 | PARD3 Entrez, Source | par-3 partitioning defective 3 homolog (C. elegans) | 2421 | 0.053 | -0.0012 | No |
| 5 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 2456 | 0.053 | 0.0153 | No |
| 6 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2716 | 0.048 | 0.0132 | No |
| 7 | LEF1 | LEF1 Entrez, Source | lymphoid enhancer-binding factor 1 | 2971 | 0.043 | 0.0098 | No |
| 8 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 3877 | 0.030 | -0.0474 | No |
| 9 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 4433 | 0.023 | -0.0808 | No |
| 10 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 4922 | 0.017 | -0.1114 | No |
| 11 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 5269 | 0.013 | -0.1327 | No |
| 12 | SSX2IP | SSX2IP Entrez, Source | synovial sarcoma, X breakpoint 2 interacting protein | 5628 | 0.009 | -0.1564 | No |
| 13 | PTPRM | PTPRM Entrez, Source | protein tyrosine phosphatase, receptor type, M | 5768 | 0.007 | -0.1643 | No |
| 14 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 5943 | 0.005 | -0.1755 | No |
| 15 | SMAD4 | SMAD4 Entrez, Source | SMAD, mothers against DPP homolog 4 (Drosophila) | 5961 | 0.005 | -0.1750 | No |
| 16 | CSNK2B | CSNK2B Entrez, Source | casein kinase 2, beta polypeptide | 6090 | 0.004 | -0.1832 | No |
| 17 | CSNK2A1 | CSNK2A1 Entrez, Source | casein kinase 2, alpha 1 polypeptide | 6396 | 0.000 | -0.2061 | No |
| 18 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 6620 | -0.002 | -0.2220 | No |
| 19 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6842 | -0.004 | -0.2372 | No |
| 20 | ACP1 | ACP1 Entrez, Source | acid phosphatase 1, soluble | 7065 | -0.006 | -0.2516 | No |
| 21 | TGFBR1 | TGFBR1 Entrez, Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 7514 | -0.011 | -0.2815 | No |
| 22 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 7869 | -0.014 | -0.3029 | No |
| 23 | ACTB | ACTB Entrez, Source | actin, beta | 8105 | -0.017 | -0.3145 | No |
| 24 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 8143 | -0.017 | -0.3111 | No |
| 25 | INSR | INSR Entrez, Source | insulin receptor | 8403 | -0.020 | -0.3234 | No |
| 26 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 8471 | -0.020 | -0.3210 | No |
| 27 | SNAI1 | SNAI1 Entrez, Source | snail homolog 1 (Drosophila) | 8517 | -0.021 | -0.3169 | No |
| 28 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 8761 | -0.023 | -0.3266 | No |
| 29 | PTPN6 | PTPN6 Entrez, Source | protein tyrosine phosphatase, non-receptor type 6 | 9104 | -0.027 | -0.3425 | No |
| 30 | BAIAP2 | BAIAP2 Entrez, Source | BAI1-associated protein 2 | 9835 | -0.035 | -0.3845 | No |
| 31 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 10127 | -0.039 | -0.3924 | No |
| 32 | PTPN1 | PTPN1 Entrez, Source | protein tyrosine phosphatase, non-receptor type 1 | 10210 | -0.040 | -0.3841 | No |
| 33 | PTPRJ | PTPRJ Entrez, Source | protein tyrosine phosphatase, receptor type, J | 10684 | -0.046 | -0.4030 | Yes |
| 34 | ACVR1C | ACVR1C Entrez, Source | activin A receptor, type IC | 10894 | -0.050 | -0.4008 | Yes |
| 35 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 11127 | -0.053 | -0.3988 | Yes |
| 36 | WASF1 | WASF1 Entrez, Source | WAS protein family, member 1 | 11176 | -0.054 | -0.3827 | Yes |
| 37 | WASL | WASL Entrez, Source | Wiskott-Aldrich syndrome-like | 11185 | -0.055 | -0.3634 | Yes |
| 38 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11323 | -0.057 | -0.3529 | Yes |
| 39 | MLLT4 | MLLT4 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 11391 | -0.059 | -0.3367 | Yes |
| 40 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 11817 | -0.068 | -0.3440 | Yes |
| 41 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11928 | -0.071 | -0.3267 | Yes |
| 42 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 11972 | -0.072 | -0.3038 | Yes |
| 43 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12184 | -0.079 | -0.2910 | Yes |
| 44 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 13036 | -0.137 | -0.3051 | Yes |
| 45 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 13148 | -0.161 | -0.2551 | Yes |
| 46 | PVRL2 | PVRL2 Entrez, Source | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 13237 | -0.215 | -0.1835 | Yes |
| 47 | LMO7 | LMO7 Entrez, Source | LIM domain 7 | 13278 | -0.252 | -0.0950 | Yes |
| 48 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13295 | -0.275 | 0.0035 | Yes |
