Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | HSA04920_ADIPOCYTOKINE_SIGNALING_PATHWAY |
| Enrichment Score (ES) | 0.39651704 |
| Normalized Enrichment Score (NES) | 1.4780432 |
| Nominal p-value | 0.017857144 |
| FDR q-value | 0.28158793 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 14 | 0.295 | 0.0914 | Yes |
| 2 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 59 | 0.201 | 0.1510 | Yes |
| 3 | PRKCQ | PRKCQ Entrez, Source | protein kinase C, theta | 147 | 0.160 | 0.1944 | Yes |
| 4 | CPT1C | CPT1C Entrez, Source | carnitine palmitoyltransferase 1C | 457 | 0.121 | 0.2090 | Yes |
| 5 | IRS1 | IRS1 Entrez, Source | insulin receptor substrate 1 | 549 | 0.114 | 0.2377 | Yes |
| 6 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 562 | 0.113 | 0.2722 | Yes |
| 7 | CAMKK1 | CAMKK1 Entrez, Source | calcium/calmodulin-dependent protein kinase kinase 1, alpha | 588 | 0.111 | 0.3050 | Yes |
| 8 | ADIPOQ | ADIPOQ Entrez, Source | adiponectin, C1Q and collagen domain containing | 852 | 0.097 | 0.3156 | Yes |
| 9 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 906 | 0.095 | 0.3414 | Yes |
| 10 | ACSL6 | ACSL6 Entrez, Source | acyl-CoA synthetase long-chain family member 6 | 937 | 0.094 | 0.3686 | Yes |
| 11 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 963 | 0.093 | 0.3958 | Yes |
| 12 | CAMKK2 | CAMKK2 Entrez, Source | calcium/calmodulin-dependent protein kinase kinase 2, beta | 1503 | 0.075 | 0.3786 | Yes |
| 13 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 1761 | 0.068 | 0.3806 | Yes |
| 14 | LEP | LEP Entrez, Source | leptin (obesity homolog, mouse) | 2177 | 0.058 | 0.3676 | Yes |
| 15 | PRKAB2 | PRKAB2 Entrez, Source | protein kinase, AMP-activated, beta 2 non-catalytic subunit | 2229 | 0.057 | 0.3815 | Yes |
| 16 | SOCS3 | SOCS3 Entrez, Source | suppressor of cytokine signaling 3 | 2264 | 0.056 | 0.3965 | Yes |
| 17 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 2509 | 0.051 | 0.3942 | No |
| 18 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 2873 | 0.045 | 0.3810 | No |
| 19 | STAT3 | STAT3 Entrez, Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 2887 | 0.045 | 0.3940 | No |
| 20 | PRKAB1 | PRKAB1 Entrez, Source | protein kinase, AMP-activated, beta 1 non-catalytic subunit | 3691 | 0.033 | 0.3438 | No |
| 21 | JAK3 | JAK3 Entrez, Source | Janus kinase 3 (a protein tyrosine kinase, leukocyte) | 4223 | 0.026 | 0.3118 | No |
| 22 | CPT1B | CPT1B Entrez, Source | carnitine palmitoyltransferase 1B (muscle) | 4432 | 0.023 | 0.3033 | No |
| 23 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 4497 | 0.022 | 0.3054 | No |
| 24 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 4872 | 0.018 | 0.2827 | No |
| 25 | PRKAA1 | PRKAA1 Entrez, Source | protein kinase, AMP-activated, alpha 1 catalytic subunit | 5388 | 0.011 | 0.2476 | No |
| 26 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 5475 | 0.010 | 0.2444 | No |
| 27 | RXRA | RXRA Entrez, Source | retinoid X receptor, alpha | 5744 | 0.007 | 0.2265 | No |
| 28 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 5868 | 0.006 | 0.2191 | No |
| 29 | PTPN11 | PTPN11 Entrez, Source | protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) | 6041 | 0.004 | 0.2074 | No |
| 30 | SLC2A1 | SLC2A1 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 1 | 6242 | 0.002 | 0.1930 | No |
| 31 | ACSL5 | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 6561 | -0.002 | 0.1695 | No |
| 32 | POMC | POMC Entrez, Source | proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin) | 6798 | -0.004 | 0.1529 | No |
| 33 | MAPK9 | MAPK9 Entrez, Source | mitogen-activated protein kinase 9 | 7208 | -0.008 | 0.1246 | No |
| 34 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 7260 | -0.008 | 0.1233 | No |
| 35 | AKT3 | AKT3 Entrez, Source | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 7266 | -0.008 | 0.1255 | No |
| 36 | ADIPOR1 | ADIPOR1 Entrez, Source | adiponectin receptor 1 | 7355 | -0.009 | 0.1217 | No |
| 37 | LEPR | LEPR Entrez, Source | leptin receptor | 7753 | -0.013 | 0.0959 | No |
| 38 | RXRG | RXRG Entrez, Source | retinoid X receptor, gamma | 7990 | -0.016 | 0.0830 | No |
| 39 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 8457 | -0.020 | 0.0543 | No |
| 40 | AKT2 | AKT2 Entrez, Source | v-akt murine thymoma viral oncogene homolog 2 | 8477 | -0.020 | 0.0593 | No |
| 41 | JAK1 | JAK1 Entrez, Source | Janus kinase 1 (a protein tyrosine kinase) | 8495 | -0.021 | 0.0644 | No |
| 42 | NFKBIB | NFKBIB Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 8711 | -0.023 | 0.0554 | No |
| 43 | PRKAG1 | PRKAG1 Entrez, Source | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 8770 | -0.023 | 0.0584 | No |
| 44 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 9040 | -0.026 | 0.0465 | No |
| 45 | PRKAG2 | PRKAG2 Entrez, Source | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 9125 | -0.027 | 0.0487 | No |
| 46 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 9174 | -0.028 | 0.0537 | No |
| 47 | PRKAA2 | PRKAA2 Entrez, Source | protein kinase, AMP-activated, alpha 2 catalytic subunit | 9876 | -0.036 | 0.0122 | No |
| 48 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 10753 | -0.047 | -0.0390 | No |
| 49 | NPY | NPY Entrez, Source | neuropeptide Y | 10886 | -0.049 | -0.0334 | No |
| 50 | FRAP1 | FRAP1 Entrez, Source | FK506 binding protein 12-rapamycin associated protein 1 | 10956 | -0.050 | -0.0229 | No |
| 51 | ACSL4 | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 11316 | -0.057 | -0.0320 | No |
| 52 | MAPK10 | MAPK10 Entrez, Source | mitogen-activated protein kinase 10 | 11586 | -0.062 | -0.0327 | No |
| 53 | ACACB | ACACB Entrez, Source | acetyl-Coenzyme A carboxylase beta | 11612 | -0.063 | -0.0150 | No |
| 54 | IKBKB | IKBKB Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 12168 | -0.078 | -0.0322 | No |
| 55 | NFKB2 | NFKB2 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 12794 | -0.110 | -0.0448 | No |
| 56 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 12964 | -0.127 | -0.0177 | No |
| 57 | JAK2 | JAK2 Entrez, Source | Janus kinase 2 (a protein tyrosine kinase) | 13089 | -0.147 | 0.0190 | No |
