Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | HYPOPHYSECTOMY_RAT_DN |
| Enrichment Score (ES) | 0.48566857 |
| Normalized Enrichment Score (NES) | 1.752542 |
| Nominal p-value | 0.0020661156 |
| FDR q-value | 0.10190375 |
| FWER p-Value | 0.995 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 44 | 0.215 | 0.1007 | Yes |
| 2 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 83 | 0.185 | 0.1874 | Yes |
| 3 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 379 | 0.127 | 0.2267 | Yes |
| 4 | CALR | CALR Entrez, Source | calreticulin | 381 | 0.127 | 0.2881 | Yes |
| 5 | MEP1B | MEP1B Entrez, Source | meprin A, beta | 758 | 0.101 | 0.3089 | Yes |
| 6 | FBLN5 | FBLN5 Entrez, Source | fibulin 5 | 1196 | 0.084 | 0.3165 | Yes |
| 7 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 1252 | 0.082 | 0.3519 | Yes |
| 8 | MGP | MGP Entrez, Source | matrix Gla protein | 1341 | 0.079 | 0.3834 | Yes |
| 9 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 1761 | 0.068 | 0.3849 | Yes |
| 10 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 1791 | 0.068 | 0.4154 | Yes |
| 11 | PIM3 | PIM3 Entrez, Source | pim-3 oncogene | 2185 | 0.058 | 0.4139 | Yes |
| 12 | DCN | DCN Entrez, Source | decorin | 2379 | 0.054 | 0.4255 | Yes |
| 13 | SLC9A1 | SLC9A1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) | 2606 | 0.050 | 0.4324 | Yes |
| 14 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 2646 | 0.049 | 0.4532 | Yes |
| 15 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 2709 | 0.048 | 0.4716 | Yes |
| 16 | PDIA3 | PDIA3 Entrez, Source | protein disulfide isomerase family A, member 3 | 3281 | 0.039 | 0.4474 | Yes |
| 17 | PEX19 | PEX19 Entrez, Source | peroxisomal biogenesis factor 19 | 3434 | 0.036 | 0.4534 | Yes |
| 18 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 3495 | 0.035 | 0.4660 | Yes |
| 19 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 3529 | 0.035 | 0.4803 | Yes |
| 20 | PADI4 | PADI4 Entrez, Source | peptidyl arginine deiminase, type IV | 3776 | 0.031 | 0.4770 | Yes |
| 21 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 3861 | 0.030 | 0.4853 | Yes |
| 22 | AHSG | AHSG Entrez, Source | alpha-2-HS-glycoprotein | 4036 | 0.028 | 0.4857 | Yes |
| 23 | NPPA | NPPA Entrez, Source | natriuretic peptide precursor A | 4369 | 0.024 | 0.4721 | No |
| 24 | FTH1 | FTH1 Entrez, Source | ferritin, heavy polypeptide 1 | 4858 | 0.018 | 0.4440 | No |
| 25 | DAD1 | DAD1 Entrez, Source | defender against cell death 1 | 5035 | 0.016 | 0.4383 | No |
| 26 | CYB5B | CYB5B Entrez, Source | cytochrome b5 type B (outer mitochondrial membrane) | 5195 | 0.014 | 0.4331 | No |
| 27 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 5260 | 0.013 | 0.4345 | No |
| 28 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 5336 | 0.012 | 0.4347 | No |
| 29 | TKT | TKT Entrez, Source | transketolase (Wernicke-Korsakoff syndrome) | 5509 | 0.010 | 0.4267 | No |
| 30 | RAB3B | RAB3B Entrez, Source | RAB3B, member RAS oncogene family | 5708 | 0.008 | 0.4155 | No |
| 31 | FN1 | FN1 Entrez, Source | fibronectin 1 | 6064 | 0.004 | 0.3908 | No |
| 32 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 6067 | 0.004 | 0.3925 | No |
| 33 | DECR1 | DECR1 Entrez, Source | 2,4-dienoyl CoA reductase 1, mitochondrial | 6290 | 0.001 | 0.3765 | No |
| 34 | B2M | B2M Entrez, Source | beta-2-microglobulin | 6897 | -0.005 | 0.3332 | No |
| 35 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 6967 | -0.005 | 0.3305 | No |
| 36 | ATP2A2 | ATP2A2 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 7144 | -0.007 | 0.3207 | No |
| 37 | TFF3 | TFF3 Entrez, Source | trefoil factor 3 (intestinal) | 7570 | -0.011 | 0.2941 | No |
| 38 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 7916 | -0.015 | 0.2753 | No |
| 39 | ARF4 | ARF4 Entrez, Source | ADP-ribosylation factor 4 | 8144 | -0.017 | 0.2664 | No |
| 40 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 8240 | -0.018 | 0.2680 | No |
| 41 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 8609 | -0.022 | 0.2509 | No |
| 42 | PPGB | PPGB Entrez, Source | protective protein for beta-galactosidase (galactosialidosis) | 8776 | -0.024 | 0.2498 | No |
| 43 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 9554 | -0.032 | 0.2069 | No |
| 44 | PSMB8 | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 10133 | -0.039 | 0.1822 | No |
| 45 | LIMS2 | LIMS2 Entrez, Source | LIM and senescent cell antigen-like domains 2 | 10214 | -0.040 | 0.1953 | No |
| 46 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12298 | -0.083 | 0.0785 | No |
