Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_24h_versus_single_gel_24h.class.cls
#double_gel_24h_versus_single_gel_24h_repos
Phenotypeclass.cls#double_gel_24h_versus_single_gel_24h_repos
Upregulated in classsingle_gel_24h
GeneSetIDENTICAL_PROTEIN_BINDING
Enrichment Score (ES)-0.34800446
Normalized Enrichment Score (NES)-1.538629
Nominal p-value0.0021008404
FDR q-value0.2722146
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: IDENTICAL_PROTEIN_BINDING   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1IGF1RIGF1R
Entrez,  Source
insulin-like growth factor 1 receptor760.1890.0149No
2CHRNA7CHRNA7
Entrez,  Source
cholinergic receptor, nicotinic, alpha 71070.1750.0317No
3TTNTTN
Entrez,  Source
titin2620.1400.0353No
4AOC3AOC3
Entrez,  Source
amine oxidase, copper containing 3 (vascular adhesion protein 1)3740.1280.0409No
5IL17FIL17F
Entrez,  Source
interleukin 17F5220.1150.0423No
6ATPIF1ATPIF1
Entrez,  Source
ATPase inhibitory factor 17410.1020.0369No
7INHBAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)11740.0850.0134No
8IGSF1IGSF1
Entrez,  Source
immunoglobulin superfamily, member 112130.0830.0196No
9USF2USF2
Entrez,  Source
upstream transcription factor 2, c-fos interacting12300.0820.0274No
10CLDN19CLDN19
Entrez,  Source
claudin 1912430.0820.0355No
11CD4CD4
Entrez,  Source
CD4 molecule12660.0810.0427No
12CLDN4CLDN4
Entrez,  Source
claudin 413700.0780.0435No
13CLDN14CLDN14
Entrez,  Source
claudin 1414500.0760.0458No
14SOX10SOX10
Entrez,  Source
SRY (sex determining region Y)-box 1014850.0750.0514No
15TRIM39TRIM39
Entrez,  Source
tripartite motif-containing 3915880.0730.0516No
16RASSF1RASSF1
Entrez,  Source
Ras association (RalGDS/AF-6) domain family 117230.0690.0490No
17CARD9CARD9
Entrez,  Source
caspase recruitment domain family, member 917270.0690.0563No
18HACL1HACL1
Entrez,  Source
2-hydroxyacyl-CoA lyase 119820.0630.0439No
19HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)21100.0600.0408No
20TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 222820.0560.0339No
21GSTK1GSTK1
Entrez,  Source
glutathione S-transferase kappa 123960.0540.0313No
22ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)24560.0530.0325No
23CEP57CEP57
Entrez,  Source
centrosomal protein 57kDa25030.0520.0347No
24SH3GL3SH3GL3
Entrez,  Source
SH3-domain GRB2-like 325570.0510.0362No
25EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)27160.0480.0294No
26SCUBE1SCUBE1
Entrez,  Source
signal peptide, CUB domain, EGF-like 129940.0430.0131No
27SP1SP1
Entrez,  Source
Sp1 transcription factor30640.0420.0124No
28PFKFB3PFKFB3
Entrez,  Source
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 332850.039-0.0001No
29MVKMVK
Entrez,  Source
mevalonate kinase (mevalonic aciduria)33440.038-0.0004No
30SUFUSUFU
Entrez,  Source
suppressor of fused homolog (Drosophila)34240.036-0.0024No
31TAX1BP1TAX1BP1
Entrez,  Source
Tax1 (human T-cell leukemia virus type I) binding protein 136830.033-0.0184No
32ADRB3ADRB3
Entrez,  Source
adrenergic, beta-3-, receptor37430.032-0.0194No
33CLDN11CLDN11
Entrez,  Source
claudin 11 (oligodendrocyte transmembrane protein)37910.031-0.0195No
34POU3F2POU3F2
Entrez,  Source
POU domain, class 3, transcription factor 239210.029-0.0261No
35DOM3ZDOM3Z
Entrez,  Source
dom-3 homolog Z (C. elegans)39680.029-0.0264No
36CLDN16CLDN16
Entrez,  Source
claudin 1640010.028-0.0258No
37ABCG4ABCG4
Entrez,  Source
ATP-binding cassette, sub-family G (WHITE), member 440600.028-0.0272No
38HSPB8HSPB8
Entrez,  Source
heat shock 22kDa protein 840930.027-0.0266No
39CD74CD74
Entrez,  Source
CD74 molecule, major histocompatibility complex, class II invariant chain41000.027-0.0241No
40TRPV4TRPV4
Entrez,  Source
transient receptor potential cation channel, subfamily V, member 445800.021-0.0582No
41BCL2L1BCL2L1
Entrez,  Source
BCL2-like 146530.020-0.0615No
42CUBNCUBN
Entrez,  Source
cubilin (intrinsic factor-cobalamin receptor)46820.020-0.0615No
43S100A1S100A1
Entrez,  Source
S100 calcium binding protein A146940.020-0.0602No
44BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 347800.019-0.0646No
45GDNFGDNF
Entrez,  Source
glial cell derived neurotrophic factor48280.018-0.0661No
46BIRC5BIRC5
Entrez,  Source
baculoviral IAP repeat-containing 5 (survivin)50830.015-0.0838No
47CASC3CASC3
Entrez,  Source
cancer susceptibility candidate 351750.014-0.0892No
48GZMAGZMA
Entrez,  Source
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)51970.014-0.0893No
49APOA2APOA2
Entrez,  Source
apolipoprotein A-II52140.014-0.0890No
50NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)52220.013-0.0880No
51TREX1TREX1
Entrez,  Source
three prime repair exonuclease 152300.013-0.0871No
52FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES52690.013-0.0886No
53BAK1BAK1
Entrez,  Source
BCL2-antagonist/killer 152810.013-0.0880No
54PYCARDPYCARD
Entrez,  Source
PYD and CARD domain containing53080.012-0.0886No
55PLOD1PLOD1
Entrez,  Source
procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 154110.011-0.0952No
56RRAGARRAGA
Entrez,  Source
Ras-related GTP binding A55430.010-0.1040No
57TERF1TERF1
Entrez,  Source
telomeric repeat binding factor (NIMA-interacting) 156670.008-0.1125No
58AGXTAGXT
Entrez,  Source
alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase)57430.007-0.1174No
59NOL3NOL3
Entrez,  Source
nucleolar protein 3 (apoptosis repressor with CARD domain)58520.006-0.1249No
60SH3GL2SH3GL2
Entrez,  Source
SH3-domain GRB2-like 258740.006-0.1259No
61SCYE1SCYE1
Entrez,  Source
small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)59240.005-0.1290No
62PVRL1PVRL1
Entrez,  Source
poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin)59430.005-0.1298No
63SMAD4SMAD4
Entrez,  Source
SMAD, mothers against DPP homolog 4 (Drosophila)59610.005-0.1305No
64FBP1FBP1
Entrez,  Source
fructose-1,6-bisphosphatase 160670.004-0.1381No
65CSNK2BCSNK2B
Entrez,  Source
casein kinase 2, beta polypeptide60900.004-0.1394No
66STK25STK25
Entrez,  Source
serine/threonine kinase 25 (STE20 homolog, yeast)61220.003-0.1413No
67HSP90AA1HSP90AA1
Entrez,  Source
heat shock protein 90kDa alpha (cytosolic), class A member 161670.003-0.1444No
68POP4POP4
Entrez,  Source
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)62690.002-0.1519No
69CLDN5CLDN5
Entrez,  Source
claudin 5 (transmembrane protein deleted in velocardiofacial syndrome)62730.002-0.1519No
70KITLGKITLG
Entrez,  Source
KIT ligand62930.001-0.1532No
71SDCBP2SDCBP2
Entrez,  Source
syndecan binding protein (syntenin) 26635-0.002-0.1789No
72ARHGDIAARHGDIA
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) alpha6645-0.002-0.1793No
73ROBO2ROBO2
Entrez,  Source
roundabout, axon guidance receptor, homolog 2 (Drosophila)6677-0.003-0.1813No
74HPRT1HPRT1
Entrez,  Source
hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)6770-0.004-0.1879No
75BCL2BCL2
Entrez,  Source
B-cell CLL/lymphoma 26812-0.004-0.1906No
76PFKFB1PFKFB1
Entrez,  Source
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 16867-0.004-0.1943No
77RUVBL2RUVBL2
Entrez,  Source
RuvB-like 2 (E. coli)6886-0.005-0.1951No
78AMBPAMBP
Entrez,  Source
alpha-1-microglobulin/bikunin precursor6890-0.005-0.1949No
79CLDN3CLDN3
Entrez,  Source
claudin 36913-0.005-0.1960No
80S100BS100B
Entrez,  Source
S100 calcium binding protein B6931-0.005-0.1968No
81ACP1ACP1
Entrez,  Source
acid phosphatase 1, soluble7065-0.006-0.2062No
82VWFVWF
Entrez,  Source
von Willebrand factor7140-0.007-0.2111No
83ITGB7ITGB7
Entrez,  Source
integrin, beta 77193-0.007-0.2142No
84APOEAPOE
Entrez,  Source
apolipoprotein E7282-0.008-0.2199No
85APOA4APOA4
Entrez,  Source
apolipoprotein A-IV7392-0.009-0.2272No
86PSME3PSME3
Entrez,  Source
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)7433-0.010-0.2292No
87CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)7499-0.010-0.2329No
88ZBTB16ZBTB16
Entrez,  Source
zinc finger and BTB domain containing 167722-0.013-0.2484No
89ALS2ALS2
Entrez,  Source
amyotrophic lateral sclerosis 2 (juvenile)7724-0.013-0.2471No
90BAXBAX
Entrez,  Source
BCL2-associated X protein7784-0.013-0.2501No
91PCBD1PCBD1
Entrez,  Source
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)7882-0.014-0.2559No
92TRPC4APTRPC4AP
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 4 associated protein7929-0.015-0.2578No
93MSH3MSH3
Entrez,  Source
mutS homolog 3 (E. coli)7967-0.015-0.2589No
94FNBP1FNBP1
Entrez,  Source
formin binding protein 18027-0.016-0.2616No
95PCMT1PCMT1
Entrez,  Source
protein-L-isoaspartate (D-aspartate) O-methyltransferase8056-0.016-0.2620No
96GOLGA5GOLGA5
Entrez,  Source
golgi autoantigen, golgin subfamily a, 58130-0.017-0.2657No
97SNRPNSNRPN
Entrez,  Source
small nuclear ribonucleoprotein polypeptide N8315-0.019-0.2776No
98SMARCA4SMARCA4
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 48374-0.019-0.2799No
99MAP3K12MAP3K12
Entrez,  Source
mitogen-activated protein kinase kinase kinase 128436-0.020-0.2823No
100ROBO1ROBO1
Entrez,  Source
roundabout, axon guidance receptor, homolog 1 (Drosophila)8442-0.020-0.2805No
101BLOC1S2BLOC1S2
Entrez,  Source
biogenesis of lysosome-related organelles complex-1, subunit 28566-0.021-0.2875No
102PSMA4PSMA4
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 48680-0.023-0.2936No
103ABCG1ABCG1
Entrez,  Source
ATP-binding cassette, sub-family G (WHITE), member 18730-0.023-0.2948No
104CDC42BPBCDC42BPB
Entrez,  Source
CDC42 binding protein kinase beta (DMPK-like)8784-0.024-0.2962No
105EIF2AK1EIF2AK1
Entrez,  Source
eukaryotic translation initiation factor 2-alpha kinase 18843-0.024-0.2980No
106MYO9BMYO9B
Entrez,  Source
myosin IXB8864-0.025-0.2968No
107ABATABAT
Entrez,  Source
4-aminobutyrate aminotransferase8902-0.025-0.2969No
108CST3CST3
Entrez,  Source
cystatin C (amyloid angiopathy and cerebral hemorrhage)8979-0.026-0.2998No
109TRADDTRADD
Entrez,  Source
TNFRSF1A-associated via death domain9040-0.026-0.3015No
110BNIP3LBNIP3L
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 3-like9084-0.027-0.3018No
111DAPK2DAPK2
Entrez,  Source
death-associated protein kinase 29112-0.027-0.3009No
112OSTF1OSTF1
Entrez,  Source
osteoclast stimulating factor 19146-0.027-0.3004No
113RELARELA
Entrez,  Source
v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)9174-0.028-0.2994No
114MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 119302-0.029-0.3059No
115TOP2ATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa9337-0.029-0.3052No
116SH3GLB1SH3GLB1
Entrez,  Source
SH3-domain GRB2-like endophilin B19390-0.030-0.3059No
117PSMA7PSMA7
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 79751-0.034-0.3295No
118VAPBVAPB
Entrez,  Source
VAMP (vesicle-associated membrane protein)-associated protein B and C9787-0.035-0.3283No
119TRIP10TRIP10
Entrez,  Source
thyroid hormone receptor interactor 109804-0.035-0.3257No
120DTNBP1DTNBP1
Entrez,  Source
dystrobrevin binding protein 19855-0.036-0.3256No
121ATXN1ATXN1
Entrez,  Source
ataxin 19911-0.036-0.3258No
122ADAM10ADAM10
Entrez,  Source
ADAM metallopeptidase domain 1010107-0.038-0.3364No
123GYS2GYS2
Entrez,  Source
glycogen synthase 2 (liver)10212-0.040-0.3400No
124ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 110218-0.040-0.3360No
125CDK2CDK2
Entrez,  Source
cyclin-dependent kinase 210352-0.041-0.3416No
126CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase10368-0.041-0.3382No
127RABAC1RABAC1
Entrez,  Source
Rab acceptor 1 (prenylated)10454-0.043-0.3400No
128TSC2TSC2
Entrez,  Source
tuberous sclerosis 210458-0.043-0.3356No
129NEFLNEFL
Entrez,  Source
neurofilament, light polypeptide 68kDa10506-0.044-0.3344No
130NFS1NFS1
Entrez,  Source
NFS1 nitrogen fixation 1 (S. cerevisiae)10672-0.046-0.3419No
131AKT1AKT1
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 110753-0.047-0.3428Yes
132CLDN8CLDN8
Entrez,  Source
claudin 810771-0.048-0.3389Yes
133HEXBHEXB
Entrez,  Source
hexosaminidase B (beta polypeptide)10854-0.049-0.3398Yes
134MYH9MYH9
Entrez,  Source
myosin, heavy chain 9, non-muscle10920-0.050-0.3393Yes
135ITGB1ITGB1
Entrez,  Source
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)11016-0.051-0.3409Yes
136PRMT2PRMT2
Entrez,  Source
protein arginine methyltransferase 211068-0.052-0.3391Yes
137BARD1BARD1
Entrez,  Source
BRCA1 associated RING domain 111085-0.053-0.3345Yes
138DFFADFFA
Entrez,  Source
DNA fragmentation factor, 45kDa, alpha polypeptide11119-0.053-0.3312Yes
139DBNLDBNL
Entrez,  Source
drebrin-like11131-0.054-0.3262Yes
140NRBP1NRBP1
Entrez,  Source
nuclear receptor binding protein 111248-0.056-0.3289Yes
141ACTN3ACTN3
Entrez,  Source
actinin, alpha 311323-0.057-0.3283Yes
142ABCG2ABCG2
Entrez,  Source
ATP-binding cassette, sub-family G (WHITE), member 211349-0.058-0.3238Yes
143PAICSPAICS
Entrez,  Source
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase11374-0.058-0.3193Yes
144DAXXDAXX
Entrez,  Source
death-associated protein 611474-0.060-0.3203Yes
145PASKPASK
Entrez,  Source
PAS domain containing serine/threonine kinase11561-0.062-0.3201Yes
146EIF2AK3EIF2AK3
Entrez,  Source
eukaryotic translation initiation factor 2-alpha kinase 311711-0.065-0.3243Yes
147ACTN4ACTN4
Entrez,  Source
actinin, alpha 411817-0.068-0.3248Yes
148XTP3TPAXTP3TPA
Entrez,  Source
-11867-0.069-0.3210Yes
149SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)11928-0.071-0.3178Yes
150APPAPP
Entrez,  Source
amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)12014-0.073-0.3163Yes
151MPGMPG
Entrez,  Source
N-methylpurine-DNA glycosylase12079-0.075-0.3129Yes
152FADDFADD
Entrez,  Source
Fas (TNFRSF6)-associated via death domain12156-0.078-0.3101Yes
153IKBKBIKBKB
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta12168-0.078-0.3024Yes
154PARP1PARP1
Entrez,  Source
poly (ADP-ribose) polymerase family, member 112319-0.083-0.3047Yes
155PAK2PAK2
Entrez,  Source
p21 (CDKN1A)-activated kinase 212379-0.086-0.2997Yes
156PRNPPRNP
Entrez,  Source
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)12448-0.089-0.2952Yes
157GNASGNAS
Entrez,  Source
GNAS complex locus12462-0.089-0.2864Yes
158PHC2PHC2
Entrez,  Source
polyhomeotic homolog 2 (Drosophila)12525-0.093-0.2809Yes
159CLDN1CLDN1
Entrez,  Source
claudin 112658-0.100-0.2801Yes
160MSH2MSH2
Entrez,  Source
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)12758-0.107-0.2758Yes
161FASFAS
Entrez,  Source
Fas (TNF receptor superfamily, member 6)12841-0.114-0.2696Yes
162IRAK2IRAK2
Entrez,  Source
interleukin-1 receptor-associated kinase 212849-0.115-0.2576Yes
163PLDNPLDN
Entrez,  Source
pallidin homolog (mouse)12874-0.118-0.2464Yes
164PTSPTS
Entrez,  Source
6-pyruvoyltetrahydropterin synthase12892-0.120-0.2346Yes
165NFKBIANFKBIA
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha12964-0.127-0.2261Yes
166MAP3K10MAP3K10
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1013023-0.135-0.2157Yes
167TRIP13TRIP13
Entrez,  Source
thyroid hormone receptor interactor 1313078-0.144-0.2040Yes
168CAV2CAV2
Entrez,  Source
caveolin 213082-0.146-0.1883Yes
169CLDN7CLDN7
Entrez,  Source
claudin 713101-0.150-0.1732Yes
170S100A11S100A11
Entrez,  Source
S100 calcium binding protein A1113140-0.159-0.1587Yes
171SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 113195-0.185-0.1426Yes
172MCM6MCM6
Entrez,  Source
MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)13196-0.186-0.1222Yes
173PVRL2PVRL2
Entrez,  Source
poliovirus receptor-related 2 (herpesvirus entry mediator B)13237-0.215-0.1017Yes
174FGFR3FGFR3
Entrez,  Source
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)13275-0.244-0.0778Yes
175ADRB2ADRB2
Entrez,  Source
adrenergic, beta-2-, receptor, surface13304-0.298-0.0473Yes
176S100A6S100A6
Entrez,  Source
S100 calcium binding protein A613330-0.4580.0009Yes
Table: GSEA details [plain text format]



Fig 2: IDENTICAL_PROTEIN_BINDING   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: IDENTICAL_PROTEIN_BINDING: Random ES distribution   
Gene set null distribution of ES for IDENTICAL_PROTEIN_BINDING