Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | IDX_TSA_DN_CLUSTER3 |
| Enrichment Score (ES) | -0.46491718 |
| Normalized Enrichment Score (NES) | -1.7373068 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.14823188 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 6 | 0.386 | 0.0921 | No |
| 2 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 105 | 0.175 | 0.1267 | No |
| 3 | FZD2 | FZD2 Entrez, Source | frizzled homolog 2 (Drosophila) | 360 | 0.129 | 0.1384 | No |
| 4 | ARMCX2 | ARMCX2 Entrez, Source | armadillo repeat containing, X-linked 2 | 1547 | 0.073 | 0.0668 | No |
| 5 | DNM1 | DNM1 Entrez, Source | dynamin 1 | 2597 | 0.050 | -0.0003 | No |
| 6 | JUP | JUP Entrez, Source | junction plakoglobin | 2926 | 0.044 | -0.0144 | No |
| 7 | RASSF5 | RASSF5 Entrez, Source | Ras association (RalGDS/AF-6) domain family 5 | 3313 | 0.038 | -0.0343 | No |
| 8 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 3375 | 0.037 | -0.0300 | No |
| 9 | PLK2 | PLK2 Entrez, Source | polo-like kinase 2 (Drosophila) | 3889 | 0.030 | -0.0614 | No |
| 10 | NDRG4 | NDRG4 Entrez, Source | NDRG family member 4 | 4055 | 0.028 | -0.0672 | No |
| 11 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 4222 | 0.026 | -0.0736 | No |
| 12 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 4288 | 0.025 | -0.0725 | No |
| 13 | GPC4 | GPC4 Entrez, Source | glypican 4 | 4613 | 0.021 | -0.0920 | No |
| 14 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 4868 | 0.018 | -0.1068 | No |
| 15 | TSPYL4 | TSPYL4 Entrez, Source | TSPY-like 4 | 5202 | 0.014 | -0.1286 | No |
| 16 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5303 | 0.013 | -0.1331 | No |
| 17 | GSTT1 | GSTT1 Entrez, Source | glutathione S-transferase theta 1 | 5866 | 0.006 | -0.1740 | No |
| 18 | ACVR2A | ACVR2A Entrez, Source | activin A receptor, type IIA | 5957 | 0.005 | -0.1796 | No |
| 19 | CCT3 | CCT3 Entrez, Source | chaperonin containing TCP1, subunit 3 (gamma) | 6694 | -0.003 | -0.2343 | No |
| 20 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 7463 | -0.010 | -0.2897 | No |
| 21 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 7490 | -0.010 | -0.2891 | No |
| 22 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 7529 | -0.011 | -0.2894 | No |
| 23 | NEDD9 | NEDD9 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 9 | 7794 | -0.013 | -0.3061 | No |
| 24 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 7976 | -0.015 | -0.3160 | No |
| 25 | SIRT2 | SIRT2 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) | 8333 | -0.019 | -0.3382 | No |
| 26 | EXOC4 | EXOC4 Entrez, Source | exocyst complex component 4 | 8337 | -0.019 | -0.3338 | No |
| 27 | SPG20 | SPG20 Entrez, Source | spastic paraplegia 20, spartin (Troyer syndrome) | 8375 | -0.019 | -0.3320 | No |
| 28 | CNN3 | CNN3 Entrez, Source | calponin 3, acidic | 9286 | -0.029 | -0.3936 | No |
| 29 | PSCD3 | PSCD3 Entrez, Source | pleckstrin homology, Sec7 and coiled-coil domains 3 | 9421 | -0.030 | -0.3963 | No |
| 30 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 9542 | -0.032 | -0.3977 | No |
| 31 | SFRP2 | SFRP2 Entrez, Source | secreted frizzled-related protein 2 | 9737 | -0.034 | -0.4041 | No |
| 32 | SKAP2 | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 10200 | -0.039 | -0.4294 | No |
| 33 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 10367 | -0.041 | -0.4319 | No |
| 34 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 10707 | -0.046 | -0.4463 | No |
| 35 | EPHX1 | EPHX1 Entrez, Source | epoxide hydrolase 1, microsomal (xenobiotic) | 10955 | -0.050 | -0.4528 | Yes |
| 36 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 10973 | -0.051 | -0.4420 | Yes |
| 37 | GGTA1 | GGTA1 Entrez, Source | glycoprotein, alpha-galactosyltransferase 1 | 11101 | -0.053 | -0.4388 | Yes |
| 38 | DOK1 | DOK1 Entrez, Source | docking protein 1, 62kDa (downstream of tyrosine kinase 1) | 11194 | -0.055 | -0.4326 | Yes |
| 39 | ANXA11 | ANXA11 Entrez, Source | annexin A11 | 11222 | -0.055 | -0.4214 | Yes |
| 40 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 11467 | -0.060 | -0.4254 | Yes |
| 41 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 11704 | -0.065 | -0.4276 | Yes |
| 42 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 11749 | -0.066 | -0.4151 | Yes |
| 43 | STXBP3 | STXBP3 Entrez, Source | syntaxin binding protein 3 | 11792 | -0.067 | -0.4022 | Yes |
| 44 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 12169 | -0.078 | -0.4117 | Yes |
| 45 | DPP7 | DPP7 Entrez, Source | dipeptidyl-peptidase 7 | 12221 | -0.080 | -0.3964 | Yes |
| 46 | SLC8A1 | SLC8A1 Entrez, Source | solute carrier family 8 (sodium/calcium exchanger), member 1 | 12331 | -0.084 | -0.3844 | Yes |
| 47 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 12350 | -0.085 | -0.3653 | Yes |
| 48 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 12422 | -0.088 | -0.3496 | Yes |
| 49 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 12660 | -0.100 | -0.3435 | Yes |
| 50 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 12854 | -0.115 | -0.3304 | Yes |
| 51 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 12899 | -0.121 | -0.3046 | Yes |
| 52 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 12923 | -0.123 | -0.2768 | Yes |
| 53 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12937 | -0.125 | -0.2477 | Yes |
| 54 | MAGED2 | MAGED2 Entrez, Source | melanoma antigen family D, 2 | 12955 | -0.127 | -0.2186 | Yes |
| 55 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 13146 | -0.160 | -0.1946 | Yes |
| 56 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13214 | -0.201 | -0.1515 | Yes |
| 57 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13312 | -0.331 | -0.0795 | Yes |
| 58 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13314 | -0.341 | 0.0021 | Yes |
