Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | IGF1PATHWAY |
| Enrichment Score (ES) | 0.5306958 |
| Normalized Enrichment Score (NES) | 1.5005944 |
| Nominal p-value | 0.044088177 |
| FDR q-value | 0.26868406 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 11 | 0.331 | 0.2981 | Yes |
| 2 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 76 | 0.189 | 0.4636 | Yes |
| 3 | IRS1 | IRS1 Entrez, Source | insulin receptor substrate 1 | 549 | 0.114 | 0.5307 | Yes |
| 4 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 1493 | 0.075 | 0.5275 | No |
| 5 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 2228 | 0.057 | 0.5237 | No |
| 6 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 4172 | 0.026 | 0.4014 | No |
| 7 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 4287 | 0.025 | 0.4152 | No |
| 8 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 4811 | 0.018 | 0.3926 | No |
| 9 | JUN | JUN Entrez, Source | jun oncogene | 4841 | 0.018 | 0.4067 | No |
| 10 | PTPN11 | PTPN11 Entrez, Source | protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) | 6041 | 0.004 | 0.3205 | No |
| 11 | CSNK2A1 | CSNK2A1 Entrez, Source | casein kinase 2, alpha 1 polypeptide | 6396 | 0.000 | 0.2942 | No |
| 12 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 6805 | -0.004 | 0.2670 | No |
| 13 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 9438 | -0.031 | 0.0972 | No |
| 14 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9624 | -0.033 | 0.1132 | No |
| 15 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 10736 | -0.047 | 0.0721 | No |
| 16 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 11353 | -0.058 | 0.0780 | No |
| 17 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12184 | -0.079 | 0.0869 | No |
