Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | IGF_VS_PDGF_UP |
| Enrichment Score (ES) | 0.42355606 |
| Normalized Enrichment Score (NES) | 1.4337965 |
| Nominal p-value | 0.04733728 |
| FDR q-value | 0.30546135 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MYBPH | MYBPH Entrez, Source | myosin binding protein H | 152 | 0.159 | 0.0520 | Yes |
| 2 | TTN | TTN Entrez, Source | titin | 262 | 0.140 | 0.0997 | Yes |
| 3 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 441 | 0.122 | 0.1352 | Yes |
| 4 | CKM | CKM Entrez, Source | creatine kinase, muscle | 445 | 0.122 | 0.1837 | Yes |
| 5 | FST | FST Entrez, Source | follistatin | 503 | 0.117 | 0.2263 | Yes |
| 6 | ATP2B4 | ATP2B4 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 4 | 620 | 0.109 | 0.2612 | Yes |
| 7 | HSPB2 | HSPB2 Entrez, Source | heat shock 27kDa protein 2 | 1028 | 0.091 | 0.2667 | Yes |
| 8 | ATP2A1 | ATP2A1 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 1072 | 0.088 | 0.2988 | Yes |
| 9 | CNR1 | CNR1 Entrez, Source | cannabinoid receptor 1 (brain) | 1085 | 0.088 | 0.3329 | Yes |
| 10 | PYGM | PYGM Entrez, Source | phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V) | 1297 | 0.080 | 0.3491 | Yes |
| 11 | SGCG | SGCG Entrez, Source | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | 1310 | 0.080 | 0.3802 | Yes |
| 12 | FMO1 | FMO1 Entrez, Source | flavin containing monooxygenase 1 | 1344 | 0.079 | 0.4092 | Yes |
| 13 | SDPR | SDPR Entrez, Source | serum deprivation response (phosphatidylserine binding protein) | 1545 | 0.074 | 0.4236 | Yes |
| 14 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 2300 | 0.055 | 0.3890 | No |
| 15 | TNNI1 | TNNI1 Entrez, Source | troponin I type 1 (skeletal, slow) | 2357 | 0.054 | 0.4066 | No |
| 16 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 2899 | 0.045 | 0.3837 | No |
| 17 | SMPX | SMPX Entrez, Source | small muscle protein, X-linked | 3280 | 0.039 | 0.3707 | No |
| 18 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 3835 | 0.031 | 0.3412 | No |
| 19 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 3861 | 0.030 | 0.3514 | No |
| 20 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 3949 | 0.029 | 0.3565 | No |
| 21 | MYOG | MYOG Entrez, Source | myogenin (myogenic factor 4) | 4784 | 0.019 | 0.3013 | No |
| 22 | ERBB3 | ERBB3 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 5405 | 0.011 | 0.2591 | No |
| 23 | RYR1 | RYR1 Entrez, Source | ryanodine receptor 1 (skeletal) | 5589 | 0.009 | 0.2491 | No |
| 24 | PPFIA4 | PPFIA4 Entrez, Source | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 5649 | 0.009 | 0.2480 | No |
| 25 | ENAH | ENAH Entrez, Source | enabled homolog (Drosophila) | 5981 | 0.005 | 0.2251 | No |
| 26 | NCAM1 | NCAM1 Entrez, Source | neural cell adhesion molecule 1 | 5996 | 0.005 | 0.2259 | No |
| 27 | MYH3 | MYH3 Entrez, Source | myosin, heavy chain 3, skeletal muscle, embryonic | 7568 | -0.011 | 0.1123 | No |
| 28 | HFE2 | HFE2 Entrez, Source | hemochromatosis type 2 (juvenile) | 8582 | -0.022 | 0.0448 | No |
| 29 | DCAMKL1 | DCAMKL1 Entrez, Source | doublecortin and CaM kinase-like 1 | 8938 | -0.025 | 0.0282 | No |
| 30 | PGAM2 | PGAM2 Entrez, Source | phosphoglycerate mutase 2 (muscle) | 8941 | -0.025 | 0.0382 | No |
| 31 | NEIL1 | NEIL1 Entrez, Source | nei endonuclease VIII-like 1 (E. coli) | 10233 | -0.040 | -0.0429 | No |
| 32 | TNNT1 | TNNT1 Entrez, Source | troponin T type 1 (skeletal, slow) | 10627 | -0.045 | -0.0544 | No |
| 33 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11323 | -0.057 | -0.0837 | No |
| 34 | SMTN | SMTN Entrez, Source | smoothelin | 11739 | -0.066 | -0.0887 | No |
| 35 | ACTC1 | ACTC1 Entrez, Source | actin, alpha, cardiac muscle 1 | 11932 | -0.071 | -0.0749 | No |
| 36 | PKIA | PKIA Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 12024 | -0.074 | -0.0523 | No |
| 37 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 12607 | -0.097 | -0.0572 | No |
| 38 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12937 | -0.125 | -0.0320 | No |
| 39 | COX6A2 | COX6A2 Entrez, Source | cytochrome c oxidase subunit VIa polypeptide 2 | 13130 | -0.156 | 0.0159 | No |
