Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | IL1RPATHWAY |
| Enrichment Score (ES) | -0.5134854 |
| Normalized Enrichment Score (NES) | -1.5797983 |
| Nominal p-value | 0.034412954 |
| FDR q-value | 0.24916808 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 763 | 0.101 | 0.0110 | No |
| 2 | IFNB1 | IFNB1 Entrez, Source | interferon, beta 1, fibroblast | 1990 | 0.063 | -0.0387 | No |
| 3 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 2040 | 0.061 | -0.0011 | No |
| 4 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 2282 | 0.056 | 0.0184 | No |
| 5 | IFNA1 | IFNA1 Entrez, Source | interferon, alpha 1 | 2866 | 0.045 | 0.0050 | No |
| 6 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3035 | 0.043 | 0.0210 | No |
| 7 | IL1RN | IL1RN Entrez, Source | interleukin 1 receptor antagonist | 3400 | 0.037 | 0.0184 | No |
| 8 | JUN | JUN Entrez, Source | jun oncogene | 4841 | 0.018 | -0.0775 | No |
| 9 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 5860 | 0.006 | -0.1500 | No |
| 10 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 6688 | -0.003 | -0.2101 | No |
| 11 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 7260 | -0.008 | -0.2475 | No |
| 12 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 8457 | -0.020 | -0.3236 | No |
| 13 | MYD88 | MYD88 Entrez, Source | myeloid differentiation primary response gene (88) | 8694 | -0.023 | -0.3260 | No |
| 14 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 9174 | -0.028 | -0.3432 | No |
| 15 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 11443 | -0.059 | -0.4734 | Yes |
| 16 | MAP2K3 | MAP2K3 Entrez, Source | mitogen-activated protein kinase kinase 3 | 11810 | -0.068 | -0.4554 | Yes |
| 17 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 12123 | -0.077 | -0.4271 | Yes |
| 18 | IKBKB | IKBKB Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 12168 | -0.078 | -0.3776 | Yes |
| 19 | IL1B | IL1B Entrez, Source | interleukin 1, beta | 12206 | -0.080 | -0.3268 | Yes |
| 20 | IRAK2 | IRAK2 Entrez, Source | interleukin-1 receptor-associated kinase 2 | 12849 | -0.115 | -0.2976 | Yes |
| 21 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 12964 | -0.127 | -0.2204 | Yes |
| 22 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 13109 | -0.151 | -0.1293 | Yes |
| 23 | IL1A | IL1A Entrez, Source | interleukin 1, alpha | 13241 | -0.218 | 0.0076 | Yes |
