Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | IL1_CORNEA_UP |
| Enrichment Score (ES) | 0.4528255 |
| Normalized Enrichment Score (NES) | 1.5385499 |
| Nominal p-value | 0.017408123 |
| FDR q-value | 0.23839599 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 126 | 0.168 | 0.0693 | Yes |
| 2 | CDX2 | CDX2 Entrez, Source | caudal type homeobox transcription factor 2 | 338 | 0.131 | 0.1150 | Yes |
| 3 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 347 | 0.130 | 0.1756 | Yes |
| 4 | TNP2 | TNP2 Entrez, Source | transition protein 2 (during histone to protamine replacement) | 488 | 0.119 | 0.2208 | Yes |
| 5 | PCP4 | PCP4 Entrez, Source | Purkinje cell protein 4 | 499 | 0.118 | 0.2754 | Yes |
| 6 | MAFK | MAFK Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) | 599 | 0.110 | 0.3198 | Yes |
| 7 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 960 | 0.093 | 0.3365 | Yes |
| 8 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 1350 | 0.079 | 0.3443 | Yes |
| 9 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1411 | 0.077 | 0.3761 | Yes |
| 10 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 1559 | 0.073 | 0.3995 | Yes |
| 11 | KDR | KDR Entrez, Source | kinase insert domain receptor (a type III receptor tyrosine kinase) | 2098 | 0.060 | 0.3873 | Yes |
| 12 | SECTM1 | SECTM1 Entrez, Source | secreted and transmembrane 1 | 2239 | 0.057 | 0.4034 | Yes |
| 13 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 2302 | 0.055 | 0.4247 | Yes |
| 14 | PDGFRA | PDGFRA Entrez, Source | platelet-derived growth factor receptor, alpha polypeptide | 2844 | 0.045 | 0.4054 | Yes |
| 15 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 2873 | 0.045 | 0.4244 | Yes |
| 16 | CXCR7 | CXCR7 Entrez, Source | chemokine (C-X-C motif) receptor 7 | 2967 | 0.044 | 0.4379 | Yes |
| 17 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3035 | 0.043 | 0.4528 | Yes |
| 18 | GFRA2 | GFRA2 Entrez, Source | GDNF family receptor alpha 2 | 3394 | 0.037 | 0.4432 | No |
| 19 | FSTL3 | FSTL3 Entrez, Source | follistatin-like 3 (secreted glycoprotein) | 3563 | 0.034 | 0.4467 | No |
| 20 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 3853 | 0.030 | 0.4392 | No |
| 21 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 4601 | 0.021 | 0.3928 | No |
| 22 | STAT4 | STAT4 Entrez, Source | signal transducer and activator of transcription 4 | 5129 | 0.015 | 0.3601 | No |
| 23 | BAK1 | BAK1 Entrez, Source | BCL2-antagonist/killer 1 | 5281 | 0.013 | 0.3547 | No |
| 24 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 6188 | 0.003 | 0.2878 | No |
| 25 | HBEGF | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 6200 | 0.002 | 0.2881 | No |
| 26 | AR | AR Entrez, Source | androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) | 6572 | -0.002 | 0.2610 | No |
| 27 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 7292 | -0.009 | 0.2110 | No |
| 28 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 7336 | -0.009 | 0.2120 | No |
| 29 | PTPRZ1 | PTPRZ1 Entrez, Source | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 7455 | -0.010 | 0.2078 | No |
| 30 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 7608 | -0.012 | 0.2019 | No |
| 31 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 7778 | -0.013 | 0.1955 | No |
| 32 | NEDD9 | NEDD9 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 9 | 7794 | -0.013 | 0.2007 | No |
| 33 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 8088 | -0.017 | 0.1864 | No |
| 34 | MERTK | MERTK Entrez, Source | c-mer proto-oncogene tyrosine kinase | 9123 | -0.027 | 0.1215 | No |
| 35 | APOD | APOD Entrez, Source | apolipoprotein D | 11002 | -0.051 | 0.0043 | No |
| 36 | SERPINB2 | SERPINB2 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 11162 | -0.054 | 0.0178 | No |
| 37 | IL1B | IL1B Entrez, Source | interleukin 1, beta | 12206 | -0.080 | -0.0232 | No |
| 38 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13262 | -0.231 | 0.0060 | No |
