Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | INTEGRINPATHWAY |
| Enrichment Score (ES) | -0.56728184 |
| Normalized Enrichment Score (NES) | -1.7617155 |
| Nominal p-value | 0.009541985 |
| FDR q-value | 0.13460314 |
| FWER p-Value | 0.992 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SRC | SRC Entrez, Source | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 729 | 0.103 | -0.0095 | No |
| 2 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 1493 | 0.075 | -0.0340 | No |
| 3 | CRKL | CRKL Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 2336 | 0.055 | -0.0732 | No |
| 4 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 3993 | 0.029 | -0.1850 | No |
| 5 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 4172 | 0.026 | -0.1870 | No |
| 6 | CSK | CSK Entrez, Source | c-src tyrosine kinase | 4360 | 0.024 | -0.1906 | No |
| 7 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 4811 | 0.018 | -0.2164 | No |
| 8 | JUN | JUN Entrez, Source | jun oncogene | 4841 | 0.018 | -0.2106 | No |
| 9 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 5269 | 0.013 | -0.2370 | No |
| 10 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 6805 | -0.004 | -0.3506 | No |
| 11 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6842 | -0.004 | -0.3515 | No |
| 12 | RAP1A | RAP1A Entrez, Source | RAP1A, member of RAS oncogene family | 8262 | -0.018 | -0.4500 | No |
| 13 | MAP2K2 | MAP2K2 Entrez, Source | mitogen-activated protein kinase kinase 2 | 8874 | -0.025 | -0.4851 | No |
| 14 | TLN1 | TLN1 Entrez, Source | talin 1 | 9094 | -0.027 | -0.4897 | No |
| 15 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9624 | -0.033 | -0.5149 | No |
| 16 | CAPN1 | CAPN1 Entrez, Source | calpain 1, (mu/I) large subunit | 10030 | -0.037 | -0.5288 | No |
| 17 | ROCK1 | ROCK1 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 1 | 10218 | -0.040 | -0.5255 | No |
| 18 | CAPNS1 | CAPNS1 Entrez, Source | calpain, small subunit 1 | 10327 | -0.041 | -0.5156 | No |
| 19 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11016 | -0.051 | -0.5448 | Yes |
| 20 | ZYX | ZYX Entrez, Source | zyxin | 11108 | -0.053 | -0.5284 | Yes |
| 21 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11323 | -0.057 | -0.5193 | Yes |
| 22 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 11607 | -0.063 | -0.5130 | Yes |
| 23 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12184 | -0.079 | -0.5217 | Yes |
| 24 | PXN | PXN Entrez, Source | paxillin | 12322 | -0.084 | -0.4953 | Yes |
| 25 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 12923 | -0.123 | -0.4862 | Yes |
| 26 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13295 | -0.275 | -0.3935 | Yes |
| 27 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -0.905 | 0.0000 | Yes |
