Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | IRITANI_ADPROX_VASC |
| Enrichment Score (ES) | -0.4790667 |
| Normalized Enrichment Score (NES) | -1.9743958 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.06820331 |
| FWER p-Value | 0.428 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TFEC | TFEC Entrez, Source | transcription factor EC | 144 | 0.160 | 0.0079 | No |
| 2 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 199 | 0.149 | 0.0213 | No |
| 3 | MLLT11 | MLLT11 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 295 | 0.136 | 0.0301 | No |
| 4 | BGN | BGN Entrez, Source | biglycan | 305 | 0.135 | 0.0451 | No |
| 5 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 491 | 0.118 | 0.0451 | No |
| 6 | LTBP2 | LTBP2 Entrez, Source | latent transforming growth factor beta binding protein 2 | 508 | 0.117 | 0.0575 | No |
| 7 | ANPEP | ANPEP Entrez, Source | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | 665 | 0.106 | 0.0582 | No |
| 8 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 677 | 0.105 | 0.0697 | No |
| 9 | IER3 | IER3 Entrez, Source | immediate early response 3 | 890 | 0.096 | 0.0649 | No |
| 10 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 1122 | 0.086 | 0.0576 | No |
| 11 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 1350 | 0.079 | 0.0496 | No |
| 12 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 1430 | 0.077 | 0.0527 | No |
| 13 | LPXN | LPXN Entrez, Source | leupaxin | 1452 | 0.076 | 0.0600 | No |
| 14 | SLC1A1 | SLC1A1 Entrez, Source | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 1453 | 0.076 | 0.0690 | No |
| 15 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 1559 | 0.073 | 0.0696 | No |
| 16 | MT1A | MT1A Entrez, Source | metallothionein 1A (functional) | 1734 | 0.069 | 0.0645 | No |
| 17 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 1805 | 0.067 | 0.0671 | No |
| 18 | MT3 | MT3 Entrez, Source | metallothionein 3 (growth inhibitory factor (neurotrophic)) | 1858 | 0.066 | 0.0709 | No |
| 19 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 1928 | 0.064 | 0.0732 | No |
| 20 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 1933 | 0.064 | 0.0804 | No |
| 21 | LAMA5 | LAMA5 Entrez, Source | laminin, alpha 5 | 1975 | 0.063 | 0.0847 | No |
| 22 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 2130 | 0.059 | 0.0801 | No |
| 23 | ICAM2 | ICAM2 Entrez, Source | intercellular adhesion molecule 2 | 2246 | 0.056 | 0.0780 | No |
| 24 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 2505 | 0.051 | 0.0645 | No |
| 25 | RGS4 | RGS4 Entrez, Source | regulator of G-protein signalling 4 | 2623 | 0.049 | 0.0615 | No |
| 26 | ECE1 | ECE1 Entrez, Source | endothelin converting enzyme 1 | 2699 | 0.048 | 0.0614 | No |
| 27 | LYL1 | LYL1 Entrez, Source | lymphoblastic leukemia derived sequence 1 | 2748 | 0.047 | 0.0633 | No |
| 28 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 2879 | 0.045 | 0.0588 | No |
| 29 | PGF | PGF Entrez, Source | placental growth factor, vascular endothelial growth factor-related protein | 2920 | 0.044 | 0.0610 | No |
| 30 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3035 | 0.043 | 0.0573 | No |
| 31 | CAP2 | CAP2 Entrez, Source | CAP, adenylate cyclase-associated protein, 2 (yeast) | 3198 | 0.040 | 0.0498 | No |
| 32 | SELP | SELP Entrez, Source | selectin P (granule membrane protein 140kDa, antigen CD62) | 3437 | 0.036 | 0.0361 | No |
| 33 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 3714 | 0.032 | 0.0190 | No |
| 34 | TGM2 | TGM2 Entrez, Source | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 3735 | 0.032 | 0.0213 | No |
| 35 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 3801 | 0.031 | 0.0200 | No |
| 36 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 3877 | 0.030 | 0.0178 | No |
| 37 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 4288 | 0.025 | -0.0102 | No |
| 38 | LAMP2 | LAMP2 Entrez, Source | lysosomal-associated membrane protein 2 | 4416 | 0.023 | -0.0171 | No |
| 39 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 4655 | 0.020 | -0.0327 | No |
| 40 | JUN | JUN Entrez, Source | jun oncogene | 4841 | 0.018 | -0.0446 | No |
| 41 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 5062 | 0.015 | -0.0594 | No |
| 42 | NISCH | NISCH Entrez, Source | nischarin | 5244 | 0.013 | -0.0715 | No |
| 43 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 5422 | 0.011 | -0.0836 | No |
| 44 | CHST1 | CHST1 Entrez, Source | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 5606 | 0.009 | -0.0963 | No |
| 45 | TCN2 | TCN2 Entrez, Source | transcobalamin II; macrocytic anemia | 6571 | -0.002 | -0.1689 | No |
| 46 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 7175 | -0.007 | -0.2136 | No |
| 47 | SRPX | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 7268 | -0.008 | -0.2196 | No |
| 48 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 7287 | -0.009 | -0.2200 | No |
| 49 | SLC3A2 | SLC3A2 Entrez, Source | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 7310 | -0.009 | -0.2206 | No |
| 50 | LPHN2 | LPHN2 Entrez, Source | latrophilin 2 | 7314 | -0.009 | -0.2198 | No |
| 51 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 7411 | -0.010 | -0.2259 | No |
| 52 | SORD | SORD Entrez, Source | sorbitol dehydrogenase | 7689 | -0.012 | -0.2454 | No |
| 53 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 7897 | -0.014 | -0.2593 | No |
| 54 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 8031 | -0.016 | -0.2675 | No |
| 55 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 8248 | -0.018 | -0.2817 | No |
| 56 | SLC6A8 | SLC6A8 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | 8500 | -0.021 | -0.2982 | No |
| 57 | SLC7A7 | SLC7A7 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 | 8722 | -0.023 | -0.3122 | No |
| 58 | PFN2 | PFN2 Entrez, Source | profilin 2 | 8811 | -0.024 | -0.3160 | No |
| 59 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 9695 | -0.034 | -0.3787 | No |
| 60 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 10033 | -0.038 | -0.3998 | No |
| 61 | UPP1 | UPP1 Entrez, Source | uridine phosphorylase 1 | 10062 | -0.038 | -0.3974 | No |
| 62 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 10067 | -0.038 | -0.3933 | No |
| 63 | EIF2B2 | EIF2B2 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | 10336 | -0.041 | -0.4087 | No |
| 64 | ENO2 | ENO2 Entrez, Source | enolase 2 (gamma, neuronal) | 10342 | -0.041 | -0.4043 | No |
| 65 | MAPKAPK3 | MAPKAPK3 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 3 | 10382 | -0.042 | -0.4024 | No |
| 66 | CLU | CLU Entrez, Source | clusterin | 10667 | -0.046 | -0.4184 | No |
| 67 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 10939 | -0.050 | -0.4330 | No |
| 68 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 11116 | -0.053 | -0.4401 | No |
| 69 | SELE | SELE Entrez, Source | selectin E (endothelial adhesion molecule 1) | 11163 | -0.054 | -0.4372 | No |
| 70 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 11718 | -0.065 | -0.4714 | Yes |
| 71 | SLC38A6 | SLC38A6 Entrez, Source | solute carrier family 38, member 6 | 11750 | -0.066 | -0.4661 | Yes |
| 72 | TXNRD2 | TXNRD2 Entrez, Source | thioredoxin reductase 2 | 11902 | -0.070 | -0.4693 | Yes |
| 73 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11928 | -0.071 | -0.4629 | Yes |
| 74 | ARL6IP5 | ARL6IP5 Entrez, Source | ADP-ribosylation-like factor 6 interacting protein 5 | 11950 | -0.071 | -0.4561 | Yes |
| 75 | CTSC | CTSC Entrez, Source | cathepsin C | 11993 | -0.073 | -0.4508 | Yes |
| 76 | PKIA | PKIA Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 12024 | -0.074 | -0.4444 | Yes |
| 77 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 12050 | -0.074 | -0.4376 | Yes |
| 78 | NRCAM | NRCAM Entrez, Source | neuronal cell adhesion molecule | 12368 | -0.086 | -0.4515 | Yes |
| 79 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 12416 | -0.088 | -0.4447 | Yes |
| 80 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 12448 | -0.089 | -0.4367 | Yes |
| 81 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 12511 | -0.092 | -0.4306 | Yes |
| 82 | MVP | MVP Entrez, Source | major vault protein | 12888 | -0.120 | -0.4450 | Yes |
| 83 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 12901 | -0.121 | -0.4317 | Yes |
| 84 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12937 | -0.125 | -0.4196 | Yes |
| 85 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 12996 | -0.131 | -0.4086 | Yes |
| 86 | NMT2 | NMT2 Entrez, Source | N-myristoyltransferase 2 | 13024 | -0.135 | -0.3948 | Yes |
| 87 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 13030 | -0.136 | -0.3793 | Yes |
| 88 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 13077 | -0.144 | -0.3659 | Yes |
| 89 | CLDN7 | CLDN7 Entrez, Source | claudin 7 | 13101 | -0.150 | -0.3500 | Yes |
| 90 | RGS10 | RGS10 Entrez, Source | regulator of G-protein signalling 10 | 13112 | -0.152 | -0.3330 | Yes |
| 91 | BASP1 | BASP1 Entrez, Source | brain abundant, membrane attached signal protein 1 | 13143 | -0.159 | -0.3166 | Yes |
| 92 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13165 | -0.168 | -0.2985 | Yes |
| 93 | FHL2 | FHL2 Entrez, Source | four and a half LIM domains 2 | 13253 | -0.222 | -0.2790 | Yes |
| 94 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13255 | -0.224 | -0.2528 | Yes |
| 95 | AGRIN | AGRIN Entrez, Source | agrin | 13266 | -0.235 | -0.2261 | Yes |
| 96 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13292 | -0.273 | -0.1960 | Yes |
| 97 | PROCR | PROCR Entrez, Source | protein C receptor, endothelial (EPCR) | 13305 | -0.301 | -0.1616 | Yes |
| 98 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 13321 | -0.364 | -0.1201 | Yes |
| 99 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 13323 | -0.371 | -0.0767 | Yes |
| 100 | TAGLN | TAGLN Entrez, Source | transgelin | 13340 | -0.666 | 0.0002 | Yes |
