Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | JAK_STAT_CASCADE |
| Enrichment Score (ES) | -0.58652467 |
| Normalized Enrichment Score (NES) | -1.7819767 |
| Nominal p-value | 0.004140787 |
| FDR q-value | 0.13908337 |
| FWER p-Value | 0.99 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SOCS3 | SOCS3 Entrez, Source | suppressor of cytokine signaling 3 | 2264 | 0.056 | -0.1303 | No |
| 2 | STAT3 | STAT3 Entrez, Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 2887 | 0.045 | -0.1453 | No |
| 3 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 3200 | 0.040 | -0.1404 | No |
| 4 | HGS | HGS Entrez, Source | hepatocyte growth factor-regulated tyrosine kinase substrate | 3319 | 0.038 | -0.1224 | No |
| 5 | SOCS1 | SOCS1 Entrez, Source | suppressor of cytokine signaling 1 | 3470 | 0.036 | -0.1085 | No |
| 6 | F2 | F2 Entrez, Source | coagulation factor II (thrombin) | 3496 | 0.035 | -0.0853 | No |
| 7 | STAT2 | STAT2 Entrez, Source | signal transducer and activator of transcription 2, 113kDa | 4290 | 0.025 | -0.1273 | No |
| 8 | HCLS1 | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 4310 | 0.025 | -0.1113 | No |
| 9 | NF2 | NF2 Entrez, Source | neurofibromin 2 (bilateral acoustic neuroma) | 5026 | 0.016 | -0.1539 | No |
| 10 | STAT4 | STAT4 Entrez, Source | signal transducer and activator of transcription 4 | 5129 | 0.015 | -0.1512 | No |
| 11 | CCR2 | CCR2 Entrez, Source | chemokine (C-C motif) receptor 2 | 5326 | 0.012 | -0.1572 | No |
| 12 | STAMBP | STAMBP Entrez, Source | STAM binding protein | 6434 | -0.000 | -0.2402 | No |
| 13 | STAT5A | STAT5A Entrez, Source | signal transducer and activator of transcription 5A | 6535 | -0.001 | -0.2469 | No |
| 14 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 7778 | -0.013 | -0.3307 | No |
| 15 | CLCF1 | CLCF1 Entrez, Source | cardiotrophin-like cytokine factor 1 | 9674 | -0.034 | -0.4491 | No |
| 16 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 9889 | -0.036 | -0.4397 | No |
| 17 | IL22RA2 | IL22RA2 Entrez, Source | interleukin 22 receptor, alpha 2 | 11846 | -0.069 | -0.5380 | Yes |
| 18 | IL12A | IL12A Entrez, Source | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 12062 | -0.075 | -0.5013 | Yes |
| 19 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 12577 | -0.095 | -0.4723 | Yes |
| 20 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 12839 | -0.114 | -0.4111 | Yes |
| 21 | NMI | NMI Entrez, Source | N-myc (and STAT) interactor | 12863 | -0.117 | -0.3302 | Yes |
| 22 | FGFR3 | FGFR3 Entrez, Source | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) | 13275 | -0.244 | -0.1881 | Yes |
| 23 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13292 | -0.273 | 0.0038 | Yes |
