Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | LEADING_EDGE |
| Enrichment Score (ES) | -0.48505688 |
| Normalized Enrichment Score (NES) | -1.5009053 |
| Nominal p-value | 0.043209877 |
| FDR q-value | 0.27279174 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EVL | EVL Entrez, Source | Enah/Vasp-like | 1214 | 0.083 | -0.0365 | No |
| 2 | ABI3 | ABI3 Entrez, Source | ABI gene family, member 3 | 2584 | 0.050 | -0.1064 | No |
| 3 | PIB5PA | PIB5PA Entrez, Source | phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A | 3072 | 0.042 | -0.1154 | No |
| 4 | APBB1 | APBB1 Entrez, Source | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 3442 | 0.036 | -0.1194 | No |
| 5 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 3801 | 0.031 | -0.1258 | No |
| 6 | FGD4 | FGD4 Entrez, Source | FYVE, RhoGEF and PH domain containing 4 | 4227 | 0.026 | -0.1409 | No |
| 7 | ARFIP2 | ARFIP2 Entrez, Source | ADP-ribosylation factor interacting protein 2 (arfaptin 2) | 4256 | 0.025 | -0.1265 | No |
| 8 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 4433 | 0.023 | -0.1247 | No |
| 9 | PDPN | PDPN Entrez, Source | podoplanin | 5603 | 0.009 | -0.2065 | No |
| 10 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6594 | -0.002 | -0.2796 | No |
| 11 | S100B | S100B Entrez, Source | S100 calcium binding protein B | 6931 | -0.005 | -0.3017 | No |
| 12 | ABI1 | ABI1 Entrez, Source | abl-interactor 1 | 7128 | -0.007 | -0.3119 | No |
| 13 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 7175 | -0.007 | -0.3105 | No |
| 14 | FGD1 | FGD1 Entrez, Source | FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia) | 7404 | -0.010 | -0.3214 | No |
| 15 | CDC42BPA | CDC42BPA Entrez, Source | CDC42 binding protein kinase alpha (DMPK-like) | 7499 | -0.010 | -0.3215 | No |
| 16 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 7724 | -0.013 | -0.3299 | No |
| 17 | NME2 | NME2 Entrez, Source | non-metastatic cells 2, protein (NM23B) expressed in | 8212 | -0.018 | -0.3548 | No |
| 18 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 8579 | -0.022 | -0.3681 | No |
| 19 | CDC42BPB | CDC42BPB Entrez, Source | CDC42 binding protein kinase beta (DMPK-like) | 8784 | -0.024 | -0.3678 | No |
| 20 | TLN1 | TLN1 Entrez, Source | talin 1 | 9094 | -0.027 | -0.3733 | No |
| 21 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 9381 | -0.030 | -0.3751 | No |
| 22 | CTTN | CTTN Entrez, Source | cortactin | 9710 | -0.034 | -0.3773 | No |
| 23 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 10920 | -0.050 | -0.4352 | Yes |
| 24 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11016 | -0.051 | -0.4086 | Yes |
| 25 | DBNL | DBNL Entrez, Source | drebrin-like | 11131 | -0.054 | -0.3820 | Yes |
| 26 | MYO5A | MYO5A Entrez, Source | myosin VA (heavy chain 12, myoxin) | 12504 | -0.092 | -0.4248 | Yes |
| 27 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 12923 | -0.123 | -0.3750 | Yes |
| 28 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 13140 | -0.159 | -0.2865 | Yes |
| 29 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 13330 | -0.458 | 0.0009 | Yes |
