Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | LEE_DENA_UP |
| Enrichment Score (ES) | -0.4354913 |
| Normalized Enrichment Score (NES) | -1.5287485 |
| Nominal p-value | 0.0332681 |
| FDR q-value | 0.2710954 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 126 | 0.168 | 0.0445 | No |
| 2 | GPC3 | GPC3 Entrez, Source | glypican 3 | 216 | 0.146 | 0.0849 | No |
| 3 | CTSS | CTSS Entrez, Source | cathepsin S | 462 | 0.120 | 0.1052 | No |
| 4 | IGFBP1 | IGFBP1 Entrez, Source | insulin-like growth factor binding protein 1 | 578 | 0.112 | 0.1324 | No |
| 5 | LPL | LPL Entrez, Source | lipoprotein lipase | 1116 | 0.087 | 0.1199 | No |
| 6 | PLEK | PLEK Entrez, Source | pleckstrin | 1498 | 0.075 | 0.1153 | No |
| 7 | LAMA5 | LAMA5 Entrez, Source | laminin, alpha 5 | 1975 | 0.063 | 0.0998 | No |
| 8 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 2427 | 0.053 | 0.0830 | No |
| 9 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 2899 | 0.045 | 0.0619 | No |
| 10 | CD24 | CD24 Entrez, Source | CD24 molecule | 3463 | 0.036 | 0.0311 | No |
| 11 | PPBP | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 3511 | 0.035 | 0.0388 | No |
| 12 | FBLN2 | FBLN2 Entrez, Source | fibulin 2 | 4077 | 0.027 | 0.0051 | No |
| 13 | SOX9 | SOX9 Entrez, Source | SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) | 4534 | 0.021 | -0.0223 | No |
| 14 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 4868 | 0.018 | -0.0416 | No |
| 15 | LCN2 | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 5994 | 0.005 | -0.1247 | No |
| 16 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 6494 | -0.001 | -0.1620 | No |
| 17 | APCS | APCS Entrez, Source | amyloid P component, serum | 6912 | -0.005 | -0.1918 | No |
| 18 | CD63 | CD63 Entrez, Source | CD63 molecule | 6996 | -0.006 | -0.1962 | No |
| 19 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 7490 | -0.010 | -0.2300 | No |
| 20 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 7517 | -0.011 | -0.2285 | No |
| 21 | TFF3 | TFF3 Entrez, Source | trefoil factor 3 (intestinal) | 7570 | -0.011 | -0.2288 | No |
| 22 | PTPRE | PTPRE Entrez, Source | protein tyrosine phosphatase, receptor type, E | 7668 | -0.012 | -0.2322 | No |
| 23 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 7738 | -0.013 | -0.2332 | No |
| 24 | LEPR | LEPR Entrez, Source | leptin receptor | 7753 | -0.013 | -0.2301 | No |
| 25 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 9777 | -0.035 | -0.3710 | No |
| 26 | MFGE8 | MFGE8 Entrez, Source | milk fat globule-EGF factor 8 protein | 10130 | -0.039 | -0.3850 | No |
| 27 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 10143 | -0.039 | -0.3734 | No |
| 28 | BCL2A1 | BCL2A1 Entrez, Source | BCL2-related protein A1 | 10553 | -0.044 | -0.3900 | No |
| 29 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 10835 | -0.049 | -0.3954 | No |
| 30 | NOTCH3 | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 11125 | -0.053 | -0.4000 | No |
| 31 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 11598 | -0.062 | -0.4154 | Yes |
| 32 | PEA15 | PEA15 Entrez, Source | phosphoprotein enriched in astrocytes 15 | 11797 | -0.067 | -0.4087 | Yes |
| 33 | B4GALT6 | B4GALT6 Entrez, Source | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | 11834 | -0.068 | -0.3895 | Yes |
| 34 | CSN3 | CSN3 Entrez, Source | casein kappa | 12274 | -0.082 | -0.3962 | Yes |
| 35 | LGMN | LGMN Entrez, Source | legumain | 12629 | -0.098 | -0.3912 | Yes |
| 36 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 12733 | -0.105 | -0.3652 | Yes |
| 37 | TAGLN2 | TAGLN2 Entrez, Source | transgelin 2 | 12779 | -0.109 | -0.3335 | Yes |
| 38 | CPE | CPE Entrez, Source | carboxypeptidase E | 13017 | -0.135 | -0.3080 | Yes |
| 39 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13196 | -0.186 | -0.2615 | Yes |
| 40 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13214 | -0.201 | -0.1982 | Yes |
| 41 | TM4SF4 | TM4SF4 Entrez, Source | transmembrane 4 L six family member 4 | 13263 | -0.233 | -0.1269 | Yes |
| 42 | ANKRD1 | ANKRD1 Entrez, Source | ankyrin repeat domain 1 (cardiac muscle) | 13328 | -0.413 | 0.0011 | Yes |
