Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | LEE_E2F1_DN |
| Enrichment Score (ES) | 0.43291092 |
| Normalized Enrichment Score (NES) | 1.4998235 |
| Nominal p-value | 0.031809144 |
| FDR q-value | 0.26831383 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 59 | 0.201 | 0.0743 | Yes |
| 2 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 63 | 0.197 | 0.1512 | Yes |
| 3 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 236 | 0.143 | 0.1944 | Yes |
| 4 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 317 | 0.133 | 0.2406 | Yes |
| 5 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 504 | 0.117 | 0.2726 | Yes |
| 6 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 601 | 0.110 | 0.3086 | Yes |
| 7 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 712 | 0.104 | 0.3409 | Yes |
| 8 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 716 | 0.103 | 0.3812 | Yes |
| 9 | PPCS | PPCS Entrez, Source | phosphopantothenoylcysteine synthetase | 1356 | 0.079 | 0.3640 | Yes |
| 10 | ZG16 | ZG16 Entrez, Source | - | 1647 | 0.071 | 0.3701 | Yes |
| 11 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 1761 | 0.068 | 0.3884 | Yes |
| 12 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 2044 | 0.061 | 0.3912 | Yes |
| 13 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 2152 | 0.059 | 0.4062 | Yes |
| 14 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 2425 | 0.053 | 0.4066 | Yes |
| 15 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 2509 | 0.051 | 0.4205 | Yes |
| 16 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2716 | 0.048 | 0.4238 | Yes |
| 17 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 2833 | 0.046 | 0.4329 | Yes |
| 18 | PXMP2 | PXMP2 Entrez, Source | peroxisomal membrane protein 2, 22kDa | 3604 | 0.034 | 0.3883 | No |
| 19 | CFH | CFH Entrez, Source | complement factor H | 3841 | 0.030 | 0.3824 | No |
| 20 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 4287 | 0.025 | 0.3587 | No |
| 21 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 5120 | 0.015 | 0.3019 | No |
| 22 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 5310 | 0.012 | 0.2926 | No |
| 23 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 5336 | 0.012 | 0.2954 | No |
| 24 | DBI | DBI Entrez, Source | diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | 5459 | 0.011 | 0.2904 | No |
| 25 | AKAP11 | AKAP11 Entrez, Source | A kinase (PRKA) anchor protein 11 | 6543 | -0.001 | 0.2095 | No |
| 26 | HADH2 | HADH2 Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase, type II | 6668 | -0.003 | 0.2012 | No |
| 27 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 6708 | -0.003 | 0.1995 | No |
| 28 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 6761 | -0.003 | 0.1969 | No |
| 29 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 7622 | -0.012 | 0.1368 | No |
| 30 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 7864 | -0.014 | 0.1243 | No |
| 31 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 7916 | -0.015 | 0.1262 | No |
| 32 | GSTO1 | GSTO1 Entrez, Source | glutathione S-transferase omega 1 | 8085 | -0.017 | 0.1201 | No |
| 33 | PNLIP | PNLIP Entrez, Source | pancreatic lipase | 8346 | -0.019 | 0.1081 | No |
| 34 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 8802 | -0.024 | 0.0833 | No |
| 35 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 9006 | -0.026 | 0.0782 | No |
| 36 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 9335 | -0.029 | 0.0651 | No |
| 37 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 9619 | -0.033 | 0.0568 | No |
| 38 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 9698 | -0.034 | 0.0642 | No |
| 39 | GHR | GHR Entrez, Source | growth hormone receptor | 10389 | -0.042 | 0.0287 | No |
| 40 | ITPR1 | ITPR1 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 1 | 10751 | -0.047 | 0.0200 | No |
| 41 | ABCG2 | ABCG2 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 2 | 11349 | -0.058 | -0.0022 | No |
| 42 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 11730 | -0.065 | -0.0051 | No |
| 43 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 11987 | -0.072 | 0.0040 | No |
| 44 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 12123 | -0.077 | 0.0240 | No |
| 45 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13176 | -0.172 | 0.0125 | No |
