Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | LE_MYELIN_UP |
| Enrichment Score (ES) | -0.5230229 |
| Normalized Enrichment Score (NES) | -1.8604956 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.102313146 |
| FWER p-Value | 0.88 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FIGNL1 | FIGNL1 Entrez, Source | fidgetin-like 1 | 383 | 0.127 | 0.0072 | No |
| 2 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 502 | 0.118 | 0.0319 | No |
| 3 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 1287 | 0.081 | -0.0041 | No |
| 4 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 1837 | 0.067 | -0.0265 | No |
| 5 | MCAM | MCAM Entrez, Source | melanoma cell adhesion molecule | 1876 | 0.065 | -0.0107 | No |
| 6 | EDNRB | EDNRB Entrez, Source | endothelin receptor type B | 2252 | 0.056 | -0.0229 | No |
| 7 | SH3GL3 | SH3GL3 Entrez, Source | SH3-domain GRB2-like 3 | 2557 | 0.051 | -0.0314 | No |
| 8 | CXCL14 | CXCL14 Entrez, Source | chemokine (C-X-C motif) ligand 14 | 2779 | 0.046 | -0.0347 | No |
| 9 | NT5DC2 | NT5DC2 Entrez, Source | 5'-nucleotidase domain containing 2 | 3917 | 0.029 | -0.1119 | No |
| 10 | EPHA5 | EPHA5 Entrez, Source | EPH receptor A5 | 3947 | 0.029 | -0.1058 | No |
| 11 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 5083 | 0.015 | -0.1869 | No |
| 12 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 6161 | 0.003 | -0.2671 | No |
| 13 | CSRP2 | CSRP2 Entrez, Source | cysteine and glycine-rich protein 2 | 6266 | 0.002 | -0.2744 | No |
| 14 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 6701 | -0.003 | -0.3062 | No |
| 15 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 6975 | -0.005 | -0.3252 | No |
| 16 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 7175 | -0.007 | -0.3381 | No |
| 17 | HDAC2 | HDAC2 Entrez, Source | histone deacetylase 2 | 7306 | -0.009 | -0.3455 | No |
| 18 | KIF22 | KIF22 Entrez, Source | kinesin family member 22 | 7498 | -0.010 | -0.3568 | No |
| 19 | POU3F1 | POU3F1 Entrez, Source | POU domain, class 3, transcription factor 1 | 7937 | -0.015 | -0.3855 | No |
| 20 | IGSF4 | IGSF4 Entrez, Source | immunoglobulin superfamily, member 4 | 8152 | -0.017 | -0.3968 | No |
| 21 | TUBB6 | TUBB6 Entrez, Source | tubulin, beta 6 | 8646 | -0.022 | -0.4275 | No |
| 22 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 8692 | -0.023 | -0.4244 | No |
| 23 | HN1 | HN1 Entrez, Source | hematological and neurological expressed 1 | 8753 | -0.023 | -0.4223 | No |
| 24 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 8905 | -0.025 | -0.4265 | No |
| 25 | P2RX4 | P2RX4 Entrez, Source | purinergic receptor P2X, ligand-gated ion channel, 4 | 9274 | -0.029 | -0.4460 | No |
| 26 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9337 | -0.029 | -0.4422 | No |
| 27 | HMGA2 | HMGA2 Entrez, Source | high mobility group AT-hook 2 | 9527 | -0.032 | -0.4474 | No |
| 28 | AURKA | AURKA Entrez, Source | aurora kinase A | 9667 | -0.034 | -0.4483 | No |
| 29 | CDC2A | 9986 | -0.037 | -0.4617 | No | ||
| 30 | CDCA8 | CDCA8 Entrez, Source | cell division cycle associated 8 | 10068 | -0.038 | -0.4570 | No |
| 31 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 10273 | -0.040 | -0.4608 | No |
| 32 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 10597 | -0.045 | -0.4724 | No |
| 33 | SPRED2 | SPRED2 Entrez, Source | sprouty-related, EVH1 domain containing 2 | 10977 | -0.051 | -0.4865 | No |
| 34 | PPP1R14B | PPP1R14B Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 14B | 11464 | -0.060 | -0.5060 | Yes |
| 35 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 11497 | -0.060 | -0.4912 | Yes |
| 36 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 11733 | -0.066 | -0.4902 | Yes |
| 37 | PDE8A | PDE8A Entrez, Source | phosphodiesterase 8A | 11766 | -0.066 | -0.4738 | Yes |
| 38 | BZW2 | BZW2 Entrez, Source | basic leucine zipper and W2 domains 2 | 12150 | -0.078 | -0.4804 | Yes |
| 39 | TCF19 | TCF19 Entrez, Source | transcription factor 19 (SC1) | 12289 | -0.082 | -0.4674 | Yes |
| 40 | COL18A1 | COL18A1 Entrez, Source | collagen, type XVIII, alpha 1 | 12394 | -0.087 | -0.4505 | Yes |
| 41 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 13021 | -0.135 | -0.4592 | Yes |
| 42 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 13084 | -0.146 | -0.4221 | Yes |
| 43 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 13097 | -0.150 | -0.3803 | Yes |
| 44 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 13105 | -0.150 | -0.3381 | Yes |
| 45 | BASP1 | BASP1 Entrez, Source | brain abundant, membrane attached signal protein 1 | 13143 | -0.159 | -0.2955 | Yes |
| 46 | PSPC1 | PSPC1 Entrez, Source | paraspeckle component 1 | 13164 | -0.168 | -0.2492 | Yes |
| 47 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13165 | -0.168 | -0.2013 | Yes |
| 48 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13194 | -0.185 | -0.1507 | Yes |
| 49 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13292 | -0.273 | -0.0803 | Yes |
| 50 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13302 | -0.295 | 0.0030 | Yes |
