Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | LINDSTEDT_DEND_8H_VS_48H_UP |
| Enrichment Score (ES) | -0.45671925 |
| Normalized Enrichment Score (NES) | -1.5878826 |
| Nominal p-value | 0.021653544 |
| FDR q-value | 0.25330085 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TFEC | TFEC Entrez, Source | transcription factor EC | 144 | 0.160 | 0.0335 | No |
| 2 | TNFSF9 | TNFSF9 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 9 | 304 | 0.135 | 0.0588 | No |
| 3 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 347 | 0.130 | 0.0916 | No |
| 4 | IL12B | IL12B Entrez, Source | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 1097 | 0.087 | 0.0593 | No |
| 5 | INHBA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 1174 | 0.085 | 0.0771 | No |
| 6 | PLEK | PLEK Entrez, Source | pleckstrin | 1498 | 0.075 | 0.0734 | No |
| 7 | CREM | CREM Entrez, Source | cAMP responsive element modulator | 1593 | 0.073 | 0.0864 | No |
| 8 | ENTPD1 | ENTPD1 Entrez, Source | ectonucleoside triphosphate diphosphohydrolase 1 | 1610 | 0.072 | 0.1052 | No |
| 9 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 2248 | 0.056 | 0.0728 | No |
| 10 | TNFRSF4 | TNFRSF4 Entrez, Source | tumor necrosis factor receptor superfamily, member 4 | 2639 | 0.049 | 0.0571 | No |
| 11 | RAB5A | RAB5A Entrez, Source | RAB5A, member RAS oncogene family | 2725 | 0.048 | 0.0639 | No |
| 12 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3035 | 0.043 | 0.0524 | No |
| 13 | IL1RN | IL1RN Entrez, Source | interleukin 1 receptor antagonist | 3400 | 0.037 | 0.0352 | No |
| 14 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 3738 | 0.032 | 0.0187 | No |
| 15 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 4006 | 0.028 | 0.0064 | No |
| 16 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 4123 | 0.027 | 0.0051 | No |
| 17 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 4288 | 0.025 | -0.0004 | No |
| 18 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 4601 | 0.021 | -0.0181 | No |
| 19 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 4604 | 0.021 | -0.0126 | No |
| 20 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 4803 | 0.018 | -0.0223 | No |
| 21 | STAT4 | STAT4 Entrez, Source | signal transducer and activator of transcription 4 | 5129 | 0.015 | -0.0427 | No |
| 22 | ACVR2A | ACVR2A Entrez, Source | activin A receptor, type IIA | 5957 | 0.005 | -0.1035 | No |
| 23 | CSF2 | CSF2 Entrez, Source | colony stimulating factor 2 (granulocyte-macrophage) | 6070 | 0.004 | -0.1109 | No |
| 24 | SLC3A2 | SLC3A2 Entrez, Source | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 7310 | -0.009 | -0.2016 | No |
| 25 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 7608 | -0.012 | -0.2208 | No |
| 26 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 7778 | -0.013 | -0.2298 | No |
| 27 | CD48 | CD48 Entrez, Source | CD48 molecule | 7841 | -0.014 | -0.2306 | No |
| 28 | TLR2 | TLR2 Entrez, Source | toll-like receptor 2 | 8424 | -0.020 | -0.2688 | No |
| 29 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 8457 | -0.020 | -0.2657 | No |
| 30 | PTGER4 | PTGER4 Entrez, Source | prostaglandin E receptor 4 (subtype EP4) | 8928 | -0.025 | -0.2940 | No |
| 31 | P2RX4 | P2RX4 Entrez, Source | purinergic receptor P2X, ligand-gated ion channel, 4 | 9274 | -0.029 | -0.3120 | No |
| 32 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 10063 | -0.038 | -0.3608 | No |
| 33 | IL7 | IL7 Entrez, Source | interleukin 7 | 11170 | -0.054 | -0.4290 | No |
| 34 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 11245 | -0.056 | -0.4191 | No |
| 35 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 11718 | -0.065 | -0.4366 | No |
| 36 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 11987 | -0.072 | -0.4367 | Yes |
| 37 | IL1B | IL1B Entrez, Source | interleukin 1, beta | 12206 | -0.080 | -0.4311 | Yes |
| 38 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 12509 | -0.092 | -0.4284 | Yes |
| 39 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 12853 | -0.115 | -0.4224 | Yes |
| 40 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 12901 | -0.121 | -0.3924 | Yes |
| 41 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13165 | -0.168 | -0.3657 | Yes |
| 42 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13214 | -0.201 | -0.3138 | Yes |
| 43 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13262 | -0.231 | -0.2534 | Yes |
| 44 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13292 | -0.273 | -0.1802 | Yes |
| 45 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13310 | -0.321 | -0.0926 | Yes |
| 46 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13315 | -0.343 | 0.0020 | Yes |
