Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | LI_FETAL_VS_WT_KIDNEY_UP |
| Enrichment Score (ES) | -0.4797225 |
| Normalized Enrichment Score (NES) | -2.0040226 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.058975004 |
| FWER p-Value | 0.304 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HERPUD1 | HERPUD1 Entrez, Source | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 74 | 0.189 | 0.0207 | No |
| 2 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 266 | 0.140 | 0.0256 | No |
| 3 | IFIT1 | IFIT1 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 1 | 366 | 0.128 | 0.0359 | No |
| 4 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 721 | 0.103 | 0.0235 | No |
| 5 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 894 | 0.096 | 0.0238 | No |
| 6 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 1122 | 0.086 | 0.0186 | No |
| 7 | PLCG2 | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 1141 | 0.086 | 0.0292 | No |
| 8 | XBP1 | XBP1 Entrez, Source | X-box binding protein 1 | 1253 | 0.082 | 0.0321 | No |
| 9 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 1287 | 0.081 | 0.0408 | No |
| 10 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 1441 | 0.077 | 0.0399 | No |
| 11 | MAGI2 | MAGI2 Entrez, Source | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 1563 | 0.073 | 0.0409 | No |
| 12 | ACSM3 | ACSM3 Entrez, Source | acyl-CoA synthetase medium-chain family member 3 | 1699 | 0.070 | 0.0404 | No |
| 13 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 1761 | 0.068 | 0.0453 | No |
| 14 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 1818 | 0.067 | 0.0503 | No |
| 15 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 1933 | 0.064 | 0.0506 | No |
| 16 | SLC30A1 | SLC30A1 Entrez, Source | solute carrier family 30 (zinc transporter), member 1 | 2087 | 0.060 | 0.0474 | No |
| 17 | KDR | KDR Entrez, Source | kinase insert domain receptor (a type III receptor tyrosine kinase) | 2098 | 0.060 | 0.0550 | No |
| 18 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 2505 | 0.051 | 0.0314 | No |
| 19 | SEPHS2 | SEPHS2 Entrez, Source | selenophosphate synthetase 2 | 2585 | 0.050 | 0.0324 | No |
| 20 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 3048 | 0.042 | 0.0034 | No |
| 21 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 4222 | 0.026 | -0.0817 | No |
| 22 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 4239 | 0.025 | -0.0794 | No |
| 23 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 4407 | 0.023 | -0.0888 | No |
| 24 | LAMP2 | LAMP2 Entrez, Source | lysosomal-associated membrane protein 2 | 4416 | 0.023 | -0.0862 | No |
| 25 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4473 | 0.022 | -0.0873 | No |
| 26 | SLC22A5 | SLC22A5 Entrez, Source | solute carrier family 22 (organic cation transporter), member 5 | 4736 | 0.019 | -0.1045 | No |
| 27 | TCF21 | TCF21 Entrez, Source | transcription factor 21 | 4856 | 0.018 | -0.1110 | No |
| 28 | TPST1 | TPST1 Entrez, Source | tyrosylprotein sulfotransferase 1 | 4909 | 0.017 | -0.1125 | No |
| 29 | GUCY1A3 | GUCY1A3 Entrez, Source | guanylate cyclase 1, soluble, alpha 3 | 5030 | 0.016 | -0.1194 | No |
| 30 | KIFC3 | KIFC3 Entrez, Source | kinesin family member C3 | 5345 | 0.012 | -0.1415 | No |
| 31 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 5422 | 0.011 | -0.1457 | No |
| 32 | DAB2 | DAB2 Entrez, Source | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 5442 | 0.011 | -0.1457 | No |
| 33 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 5860 | 0.006 | -0.1763 | No |
| 34 | PGRMC2 | PGRMC2 Entrez, Source | progesterone receptor membrane component 2 | 6040 | 0.004 | -0.1893 | No |
| 35 | ITM2B | ITM2B Entrez, Source | integral membrane protein 2B | 6118 | 0.003 | -0.1946 | No |
| 36 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 6188 | 0.003 | -0.1995 | No |
| 37 | HRSP12 | HRSP12 Entrez, Source | heat-responsive protein 12 | 6345 | 0.001 | -0.2112 | No |
| 38 | HPN | HPN Entrez, Source | hepsin (transmembrane protease, serine 1) | 6394 | 0.000 | -0.2147 | No |
| 39 | TGOLN2 | TGOLN2 Entrez, Source | trans-golgi network protein 2 | 6479 | -0.001 | -0.2210 | No |
| 40 | TSPO | TSPO Entrez, Source | translocator protein (18kDa) | 6559 | -0.002 | -0.2268 | No |
| 41 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 6620 | -0.002 | -0.2310 | No |
| 42 | FGF9 | FGF9 Entrez, Source | fibroblast growth factor 9 (glia-activating factor) | 6646 | -0.002 | -0.2326 | No |
| 43 | TRIM2 | TRIM2 Entrez, Source | tripartite motif-containing 2 | 6833 | -0.004 | -0.2461 | No |
| 44 | CLDN3 | CLDN3 Entrez, Source | claudin 3 | 6913 | -0.005 | -0.2514 | No |
| 45 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 6990 | -0.006 | -0.2563 | No |
| 46 | CDS1 | CDS1 Entrez, Source | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 7104 | -0.007 | -0.2640 | No |
| 47 | ANGPT1 | ANGPT1 Entrez, Source | angiopoietin 1 | 7146 | -0.007 | -0.2661 | No |
| 48 | APOM | APOM Entrez, Source | apolipoprotein M | 7231 | -0.008 | -0.2713 | No |
| 49 | APOE | APOE Entrez, Source | apolipoprotein E | 7282 | -0.008 | -0.2739 | No |
| 50 | PMP22 | PMP22 Entrez, Source | peripheral myelin protein 22 | 7414 | -0.010 | -0.2825 | No |
| 51 | TMED5 | TMED5 Entrez, Source | transmembrane emp24 protein transport domain containing 5 | 7444 | -0.010 | -0.2833 | No |
| 52 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 7490 | -0.010 | -0.2853 | No |
| 53 | LEPR | LEPR Entrez, Source | leptin receptor | 7753 | -0.013 | -0.3032 | No |
| 54 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 7766 | -0.013 | -0.3023 | No |
| 55 | IMPA2 | IMPA2 Entrez, Source | inositol(myo)-1(or 4)-monophosphatase 2 | 7830 | -0.014 | -0.3052 | No |
| 56 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 7864 | -0.014 | -0.3057 | No |
| 57 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 8802 | -0.024 | -0.3732 | No |
| 58 | MERTK | MERTK Entrez, Source | c-mer proto-oncogene tyrosine kinase | 9123 | -0.027 | -0.3936 | No |
| 59 | PLS3 | PLS3 Entrez, Source | plastin 3 (T isoform) | 9132 | -0.027 | -0.3904 | No |
| 60 | CTSH | CTSH Entrez, Source | cathepsin H | 9659 | -0.033 | -0.4255 | No |
| 61 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 9861 | -0.036 | -0.4357 | No |
| 62 | CAST | CAST Entrez, Source | calpastatin | 10118 | -0.039 | -0.4497 | No |
| 63 | ATP1A1 | ATP1A1 Entrez, Source | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 10291 | -0.041 | -0.4571 | No |
| 64 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 10357 | -0.041 | -0.4563 | No |
| 65 | FAM3C | FAM3C Entrez, Source | family with sequence similarity 3, member C | 10573 | -0.044 | -0.4664 | No |
| 66 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 10628 | -0.045 | -0.4642 | No |
| 67 | CLU | CLU Entrez, Source | clusterin | 10667 | -0.046 | -0.4607 | No |
| 68 | SYNGR2 | SYNGR2 Entrez, Source | synaptogyrin 2 | 10737 | -0.047 | -0.4594 | No |
| 69 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 10920 | -0.050 | -0.4663 | No |
| 70 | SLC35A3 | SLC35A3 Entrez, Source | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 11099 | -0.053 | -0.4724 | Yes |
| 71 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 11116 | -0.053 | -0.4662 | Yes |
| 72 | GNG11 | GNG11 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 11 | 11142 | -0.054 | -0.4607 | Yes |
| 73 | DUSP9 | DUSP9 Entrez, Source | dual specificity phosphatase 9 | 11183 | -0.054 | -0.4561 | Yes |
| 74 | CREBL2 | CREBL2 Entrez, Source | cAMP responsive element binding protein-like 2 | 11190 | -0.055 | -0.4490 | Yes |
| 75 | FPGT | FPGT Entrez, Source | fucose-1-phosphate guanylyltransferase | 11272 | -0.056 | -0.4473 | Yes |
| 76 | PEX7 | PEX7 Entrez, Source | peroxisomal biogenesis factor 7 | 11330 | -0.057 | -0.4436 | Yes |
| 77 | BPGM | BPGM Entrez, Source | 2,3-bisphosphoglycerate mutase | 11356 | -0.058 | -0.4375 | Yes |
| 78 | SMPDL3A | SMPDL3A Entrez, Source | sphingomyelin phosphodiesterase, acid-like 3A | 11365 | -0.058 | -0.4301 | Yes |
| 79 | ST3GAL6 | ST3GAL6 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 11435 | -0.059 | -0.4270 | Yes |
| 80 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 11458 | -0.060 | -0.4204 | Yes |
| 81 | CRYAB | CRYAB Entrez, Source | crystallin, alpha B | 11652 | -0.064 | -0.4262 | Yes |
| 82 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 11707 | -0.065 | -0.4213 | Yes |
| 83 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 11713 | -0.065 | -0.4126 | Yes |
| 84 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 11744 | -0.066 | -0.4058 | Yes |
| 85 | PDE8A | PDE8A Entrez, Source | phosphodiesterase 8A | 11766 | -0.066 | -0.3981 | Yes |
| 86 | VLDLR | VLDLR Entrez, Source | very low density lipoprotein receptor | 11859 | -0.069 | -0.3955 | Yes |
| 87 | ENPEP | ENPEP Entrez, Source | glutamyl aminopeptidase (aminopeptidase A) | 11892 | -0.070 | -0.3883 | Yes |
| 88 | TFPI | TFPI Entrez, Source | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 12015 | -0.073 | -0.3873 | Yes |
| 89 | GNG12 | GNG12 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 12 | 12090 | -0.076 | -0.3824 | Yes |
| 90 | CYB5A | CYB5A Entrez, Source | cytochrome b5 type A (microsomal) | 12147 | -0.078 | -0.3759 | Yes |
| 91 | ELF1 | ELF1 Entrez, Source | E74-like factor 1 (ets domain transcription factor) | 12250 | -0.081 | -0.3723 | Yes |
| 92 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 12281 | -0.082 | -0.3632 | Yes |
| 93 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 12448 | -0.089 | -0.3635 | Yes |
| 94 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 12577 | -0.095 | -0.3599 | Yes |
| 95 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 12641 | -0.099 | -0.3509 | Yes |
| 96 | PODXL | PODXL Entrez, Source | podocalyxin-like | 12713 | -0.104 | -0.3418 | Yes |
| 97 | ASAH1 | ASAH1 Entrez, Source | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 12784 | -0.110 | -0.3319 | Yes |
| 98 | CRYZ | CRYZ Entrez, Source | crystallin, zeta (quinone reductase) | 12993 | -0.131 | -0.3294 | Yes |
| 99 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 13011 | -0.133 | -0.3122 | Yes |
| 100 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 13030 | -0.136 | -0.2947 | Yes |
| 101 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 13036 | -0.137 | -0.2761 | Yes |
| 102 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 13072 | -0.143 | -0.2588 | Yes |
| 103 | CAV2 | CAV2 Entrez, Source | caveolin 2 | 13082 | -0.146 | -0.2392 | Yes |
| 104 | DYNC2LI1 | DYNC2LI1 Entrez, Source | dynein, cytoplasmic 2, light intermediate chain 1 | 13099 | -0.150 | -0.2196 | Yes |
| 105 | PRPS2 | PRPS2 Entrez, Source | phosphoribosyl pyrophosphate synthetase 2 | 13107 | -0.151 | -0.1992 | Yes |
| 106 | SERINC5 | SERINC5 Entrez, Source | serine incorporator 5 | 13200 | -0.190 | -0.1798 | Yes |
| 107 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13255 | -0.224 | -0.1527 | Yes |
| 108 | AGRIN | AGRIN Entrez, Source | agrin | 13266 | -0.235 | -0.1209 | Yes |
| 109 | FGFR3 | FGFR3 Entrez, Source | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) | 13275 | -0.244 | -0.0876 | Yes |
| 110 | AHNAK | AHNAK Entrez, Source | AHNAK nucleoprotein (desmoyokin) | 13307 | -0.312 | -0.0466 | Yes |
| 111 | GNAI1 | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 13318 | -0.354 | 0.0018 | Yes |
