Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | MAPK_CASCADE |
| Enrichment Score (ES) | -0.4953674 |
| Normalized Enrichment Score (NES) | -1.492193 |
| Nominal p-value | 0.069716774 |
| FDR q-value | 0.2762518 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 2040 | 0.061 | -0.0949 | No |
| 2 | SIPA1 | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 2822 | 0.046 | -0.1099 | No |
| 3 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 4172 | 0.026 | -0.1865 | No |
| 4 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 4811 | 0.018 | -0.2169 | No |
| 5 | JUN | JUN Entrez, Source | jun oncogene | 4841 | 0.018 | -0.2019 | No |
| 6 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 6688 | -0.003 | -0.3378 | No |
| 7 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6842 | -0.004 | -0.3454 | No |
| 8 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 7416 | -0.010 | -0.3792 | No |
| 9 | RASA3 | RASA3 Entrez, Source | RAS p21 protein activator 3 | 7585 | -0.011 | -0.3811 | No |
| 10 | MAP3K12 | MAP3K12 Entrez, Source | mitogen-activated protein kinase kinase kinase 12 | 8436 | -0.020 | -0.4259 | No |
| 11 | MAP2K2 | MAP2K2 Entrez, Source | mitogen-activated protein kinase kinase 2 | 8874 | -0.025 | -0.4352 | No |
| 12 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9624 | -0.033 | -0.4599 | Yes |
| 13 | PLCB3 | PLCB3 Entrez, Source | phospholipase C, beta 3 (phosphatidylinositol-specific) | 10097 | -0.038 | -0.4589 | Yes |
| 14 | MBP | MBP Entrez, Source | myelin basic protein | 10406 | -0.042 | -0.4422 | Yes |
| 15 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 10736 | -0.047 | -0.4224 | Yes |
| 16 | NRAS | NRAS Entrez, Source | neuroblastoma RAS viral (v-ras) oncogene homolog | 11369 | -0.058 | -0.4147 | Yes |
| 17 | BRAF | BRAF Entrez, Source | v-raf murine sarcoma viral oncogene homolog B1 | 11372 | -0.058 | -0.3595 | Yes |
| 18 | ARAF | ARAF Entrez, Source | v-raf murine sarcoma 3611 viral oncogene homolog | 11403 | -0.059 | -0.3058 | Yes |
| 19 | MAPK12 | MAPK12 Entrez, Source | mitogen-activated protein kinase 12 | 11422 | -0.059 | -0.2510 | Yes |
| 20 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 11443 | -0.059 | -0.1960 | Yes |
| 21 | KRAS | KRAS Entrez, Source | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 11456 | -0.060 | -0.1402 | Yes |
| 22 | MAPK10 | MAPK10 Entrez, Source | mitogen-activated protein kinase 10 | 11586 | -0.062 | -0.0908 | Yes |
| 23 | MAP2K3 | MAP2K3 Entrez, Source | mitogen-activated protein kinase kinase 3 | 11810 | -0.068 | -0.0432 | Yes |
| 24 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12184 | -0.079 | 0.0037 | Yes |
| 25 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 12415 | -0.087 | 0.0696 | Yes |
