Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | MCALPAINPATHWAY |
| Enrichment Score (ES) | -0.5294387 |
| Normalized Enrichment Score (NES) | -1.5621847 |
| Nominal p-value | 0.04192872 |
| FDR q-value | 0.25340894 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 392 | 0.126 | 0.0351 | No |
| 2 | CXCR3 | CXCR3 Entrez, Source | chemokine (C-X-C motif) receptor 3 | 648 | 0.107 | 0.0708 | No |
| 3 | PRKAR1B | PRKAR1B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, beta | 2459 | 0.052 | -0.0382 | No |
| 4 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2716 | 0.048 | -0.0329 | No |
| 5 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 3993 | 0.029 | -0.1141 | No |
| 6 | PRKAR2A | PRKAR2A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, alpha | 4888 | 0.018 | -0.1722 | No |
| 7 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6842 | -0.004 | -0.3167 | No |
| 8 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 7099 | -0.007 | -0.3326 | No |
| 9 | TLN1 | TLN1 Entrez, Source | talin 1 | 9094 | -0.027 | -0.4684 | No |
| 10 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9624 | -0.033 | -0.4912 | Yes |
| 11 | CAPN2 | CAPN2 Entrez, Source | calpain 2, (m/II) large subunit | 9763 | -0.035 | -0.4838 | Yes |
| 12 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 9892 | -0.036 | -0.4749 | Yes |
| 13 | MYL2 | MYL2 Entrez, Source | myosin, light chain 2, regulatory, cardiac, slow | 9897 | -0.036 | -0.4567 | Yes |
| 14 | CAPN1 | CAPN1 Entrez, Source | calpain 1, (mu/I) large subunit | 10030 | -0.037 | -0.4474 | Yes |
| 15 | CAPNS1 | CAPNS1 Entrez, Source | calpain, small subunit 1 | 10327 | -0.041 | -0.4487 | Yes |
| 16 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11016 | -0.051 | -0.4740 | Yes |
| 17 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 11607 | -0.063 | -0.4862 | Yes |
| 18 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12184 | -0.079 | -0.4890 | Yes |
| 19 | PXN | PXN Entrez, Source | paxillin | 12322 | -0.084 | -0.4565 | Yes |
| 20 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 13021 | -0.135 | -0.4397 | Yes |
| 21 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -0.905 | 0.0000 | Yes |
