Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | METAL_ION_TRANSPORT |
| Enrichment Score (ES) | 0.42082876 |
| Normalized Enrichment Score (NES) | 1.7056379 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.12953672 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PLN | PLN Entrez, Source | phospholamban | 12 | 0.308 | 0.0719 | Yes |
| 2 | CHRNA7 | CHRNA7 Entrez, Source | cholinergic receptor, nicotinic, alpha 7 | 107 | 0.175 | 0.1061 | Yes |
| 3 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 433 | 0.123 | 0.1106 | Yes |
| 4 | ABCC8 | ABCC8 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | 472 | 0.120 | 0.1361 | Yes |
| 5 | KCNB2 | KCNB2 Entrez, Source | potassium voltage-gated channel, Shab-related subfamily, member 2 | 483 | 0.119 | 0.1634 | Yes |
| 6 | KCNJ4 | KCNJ4 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 4 | 546 | 0.114 | 0.1856 | Yes |
| 7 | KCNV1 | KCNV1 Entrez, Source | potassium channel, subfamily V, member 1 | 687 | 0.105 | 0.1998 | Yes |
| 8 | SCN2B | SCN2B Entrez, Source | sodium channel, voltage-gated, type II, beta | 689 | 0.105 | 0.2245 | Yes |
| 9 | TRPV5 | TRPV5 Entrez, Source | transient receptor potential cation channel, subfamily V, member 5 | 903 | 0.095 | 0.2309 | Yes |
| 10 | KCNN3 | KCNN3 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 | 1040 | 0.090 | 0.2419 | Yes |
| 11 | CACNA2D1 | CACNA2D1 Entrez, Source | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 1054 | 0.089 | 0.2620 | Yes |
| 12 | ATP2A1 | ATP2A1 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 1072 | 0.088 | 0.2817 | Yes |
| 13 | KCNJ6 | KCNJ6 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 6 | 1102 | 0.087 | 0.3000 | Yes |
| 14 | KCNAB1 | KCNAB1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | 1117 | 0.087 | 0.3195 | Yes |
| 15 | TRPC3 | TRPC3 Entrez, Source | transient receptor potential cation channel, subfamily C, member 3 | 1352 | 0.079 | 0.3204 | Yes |
| 16 | SCNN1G | SCNN1G Entrez, Source | sodium channel, nonvoltage-gated 1, gamma | 1742 | 0.069 | 0.3073 | Yes |
| 17 | SCN10A | SCN10A Entrez, Source | sodium channel, voltage-gated, type X, alpha | 1814 | 0.067 | 0.3178 | Yes |
| 18 | ATP2A3 | ATP2A3 Entrez, Source | ATPase, Ca++ transporting, ubiquitous | 1912 | 0.064 | 0.3257 | Yes |
| 19 | SCN4B | SCN4B Entrez, Source | sodium channel, voltage-gated, type IV, beta | 1965 | 0.063 | 0.3368 | Yes |
| 20 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 2132 | 0.059 | 0.3383 | Yes |
| 21 | CACNB3 | CACNB3 Entrez, Source | calcium channel, voltage-dependent, beta 3 subunit | 2538 | 0.051 | 0.3197 | Yes |
| 22 | KCNH3 | KCNH3 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 3 | 2561 | 0.050 | 0.3300 | Yes |
| 23 | KCNH4 | KCNH4 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 2628 | 0.049 | 0.3367 | Yes |
| 24 | KCNMB1 | KCNMB1 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 1 | 2672 | 0.049 | 0.3449 | Yes |
| 25 | CSN2 | CSN2 Entrez, Source | casein beta | 2737 | 0.047 | 0.3513 | Yes |
| 26 | ATP7A | ATP7A Entrez, Source | ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) | 2970 | 0.043 | 0.3441 | Yes |
| 27 | CACNA1D | CACNA1D Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1D subunit | 3122 | 0.041 | 0.3424 | Yes |
| 28 | KCNA2 | KCNA2 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 2 | 3251 | 0.039 | 0.3420 | Yes |
| 29 | KCNH2 | KCNH2 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 3257 | 0.039 | 0.3509 | Yes |
| 30 | KCNS1 | KCNS1 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 | 3324 | 0.038 | 0.3549 | Yes |
| 31 | KCNK1 | KCNK1 Entrez, Source | potassium channel, subfamily K, member 1 | 3345 | 0.037 | 0.3622 | Yes |
| 32 | KCNN4 | KCNN4 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 | 3482 | 0.035 | 0.3604 | Yes |
| 33 | KCNJ2 | KCNJ2 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 2 | 3503 | 0.035 | 0.3672 | Yes |
| 34 | SLC34A3 | SLC34A3 Entrez, Source | solute carrier family 34 (sodium phosphate), member 3 | 3619 | 0.033 | 0.3664 | Yes |
| 35 | HFE | HFE Entrez, Source | hemochromatosis | 3648 | 0.033 | 0.3721 | Yes |
| 36 | KCNE2 | KCNE2 Entrez, Source | potassium voltage-gated channel, Isk-related family, member 2 | 3669 | 0.033 | 0.3784 | Yes |
| 37 | KCNAB3 | KCNAB3 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, beta member 3 | 3756 | 0.032 | 0.3794 | Yes |
| 38 | SCN5A | SCN5A Entrez, Source | sodium channel, voltage-gated, type V, alpha (long QT syndrome 3) | 3775 | 0.032 | 0.3855 | Yes |
| 39 | KCNC3 | KCNC3 Entrez, Source | potassium voltage-gated channel, Shaw-related subfamily, member 3 | 3788 | 0.031 | 0.3920 | Yes |
| 40 | KCND3 | KCND3 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 3 | 3813 | 0.031 | 0.3975 | Yes |
| 41 | SCN7A | SCN7A Entrez, Source | sodium channel, voltage-gated, type VII, alpha | 3851 | 0.030 | 0.4018 | Yes |
| 42 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 3853 | 0.030 | 0.4089 | Yes |
| 43 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 3892 | 0.030 | 0.4131 | Yes |
| 44 | KCNA5 | KCNA5 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 5 | 3911 | 0.030 | 0.4187 | Yes |
| 45 | SLN | SLN Entrez, Source | sarcolipin | 4026 | 0.028 | 0.4167 | Yes |
| 46 | KCNMB4 | KCNMB4 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 4 | 4059 | 0.028 | 0.4208 | Yes |
| 47 | KCNQ2 | KCNQ2 Entrez, Source | potassium voltage-gated channel, KQT-like subfamily, member 2 | 4151 | 0.026 | 0.4202 | No |
| 48 | TRPC5 | TRPC5 Entrez, Source | transient receptor potential cation channel, subfamily C, member 5 | 4328 | 0.024 | 0.4126 | No |
| 49 | TRPC4 | TRPC4 Entrez, Source | transient receptor potential cation channel, subfamily C, member 4 | 4722 | 0.019 | 0.3875 | No |
| 50 | KCNJ3 | KCNJ3 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 3 | 4792 | 0.019 | 0.3867 | No |
| 51 | KCNH1 | KCNH1 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 1 | 4830 | 0.018 | 0.3882 | No |
| 52 | KCNA3 | KCNA3 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 3 | 4844 | 0.018 | 0.3915 | No |
| 53 | KCNQ3 | KCNQ3 Entrez, Source | potassium voltage-gated channel, KQT-like subfamily, member 3 | 4990 | 0.016 | 0.3844 | No |
| 54 | COX17 | COX17 Entrez, Source | COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) | 5087 | 0.015 | 0.3807 | No |
| 55 | KCNS3 | KCNS3 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 | 5174 | 0.014 | 0.3775 | No |
| 56 | KCNA4 | KCNA4 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 4 | 5299 | 0.013 | 0.3711 | No |
| 57 | NMUR2 | NMUR2 Entrez, Source | neuromedin U receptor 2 | 5367 | 0.012 | 0.3688 | No |
| 58 | SCN11A | SCN11A Entrez, Source | sodium channel, voltage-gated, type XI, alpha | 5399 | 0.011 | 0.3692 | No |
| 59 | SLC11A2 | SLC11A2 Entrez, Source | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 5523 | 0.010 | 0.3623 | No |
| 60 | KCNN1 | KCNN1 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 | 5531 | 0.010 | 0.3641 | No |
| 61 | SCN4A | SCN4A Entrez, Source | sodium channel, voltage-gated, type IV, alpha | 5567 | 0.009 | 0.3637 | No |
| 62 | RYR1 | RYR1 Entrez, Source | ryanodine receptor 1 (skeletal) | 5589 | 0.009 | 0.3643 | No |
| 63 | KCNIP2 | KCNIP2 Entrez, Source | Kv channel interacting protein 2 | 5898 | 0.006 | 0.3423 | No |
| 64 | KCNJ15 | KCNJ15 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 15 | 6003 | 0.005 | 0.3356 | No |
| 65 | KCNE1 | KCNE1 Entrez, Source | potassium voltage-gated channel, Isk-related family, member 1 | 6053 | 0.004 | 0.3328 | No |
| 66 | ATOX1 | ATOX1 Entrez, Source | ATX1 antioxidant protein 1 homolog (yeast) | 6155 | 0.003 | 0.3259 | No |
| 67 | SCN9A | SCN9A Entrez, Source | sodium channel, voltage-gated, type IX, alpha | 6177 | 0.003 | 0.3249 | No |
| 68 | KCNG2 | KCNG2 Entrez, Source | potassium voltage-gated channel, subfamily G, member 2 | 6206 | 0.002 | 0.3234 | No |
| 69 | NMUR1 | NMUR1 Entrez, Source | neuromedin U receptor 1 | 6304 | 0.001 | 0.3163 | No |
| 70 | KCNJ5 | KCNJ5 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 5 | 6426 | -0.000 | 0.3072 | No |
| 71 | SCN1B | SCN1B Entrez, Source | sodium channel, voltage-gated, type I, beta | 6455 | -0.000 | 0.3052 | No |
| 72 | KCNC1 | KCNC1 Entrez, Source | potassium voltage-gated channel, Shaw-related subfamily, member 1 | 6848 | -0.004 | 0.2766 | No |
| 73 | KCNQ1 | KCNQ1 Entrez, Source | potassium voltage-gated channel, KQT-like subfamily, member 1 | 6895 | -0.005 | 0.2742 | No |
| 74 | CCS | CCS Entrez, Source | copper chaperone for superoxide dismutase | 7212 | -0.008 | 0.2522 | No |
| 75 | CACNB4 | CACNB4 Entrez, Source | calcium channel, voltage-dependent, beta 4 subunit | 7521 | -0.011 | 0.2315 | No |
| 76 | ABCC9 | ABCC9 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | 7637 | -0.012 | 0.2256 | No |
| 77 | KCNJ10 | KCNJ10 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 10 | 7799 | -0.014 | 0.2166 | No |
| 78 | ATP7B | ATP7B Entrez, Source | ATPase, Cu++ transporting, beta polypeptide | 8306 | -0.019 | 0.1829 | No |
| 79 | KCNJ1 | KCNJ1 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 1 | 8394 | -0.020 | 0.1810 | No |
| 80 | KCNJ12 | KCNJ12 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 12 | 8416 | -0.020 | 0.1841 | No |
| 81 | KCNJ11 | KCNJ11 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 11 | 8880 | -0.025 | 0.1550 | No |
| 82 | SLC31A1 | SLC31A1 Entrez, Source | solute carrier family 31 (copper transporters), member 1 | 8908 | -0.025 | 0.1589 | No |
| 83 | CHP | CHP Entrez, Source | - | 9731 | -0.034 | 0.1050 | No |
| 84 | SLC40A1 | SLC40A1 Entrez, Source | solute carrier family 40 (iron-regulated transporter), member 1 | 10093 | -0.038 | 0.0868 | No |
| 85 | TRPM2 | TRPM2 Entrez, Source | transient receptor potential cation channel, subfamily M, member 2 | 10275 | -0.040 | 0.0826 | No |
| 86 | NPY | NPY Entrez, Source | neuropeptide Y | 10886 | -0.049 | 0.0483 | No |
| 87 | TRPC1 | TRPC1 Entrez, Source | transient receptor potential cation channel, subfamily C, member 1 | 11504 | -0.060 | 0.0160 | No |
| 88 | SLC17A3 | SLC17A3 Entrez, Source | solute carrier family 17 (sodium phosphate), member 3 | 11551 | -0.061 | 0.0271 | No |
| 89 | ATP1A4 | ATP1A4 Entrez, Source | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 11791 | -0.067 | 0.0249 | No |
| 90 | SLC8A1 | SLC8A1 Entrez, Source | solute carrier family 8 (sodium/calcium exchanger), member 1 | 12331 | -0.084 | 0.0041 | No |
| 91 | ATP2C1 | ATP2C1 Entrez, Source | ATPase, Ca++ transporting, type 2C, member 1 | 12741 | -0.106 | -0.0017 | No |
| 92 | SLC31A2 | SLC31A2 Entrez, Source | solute carrier family 31 (copper transporters), member 2 | 13212 | -0.199 | 0.0098 | No |
